Cleveland Guardians at Chicago White Sox odds, picks and predictions

Analyzing Friday’s Cleveland Guardians at Chicago White Sox odds and lines, with MLB expert picks, predictions and best bets.

The Cleveland Guardians (52-51) will play the 2nd game of a 4-game series against the Chicago White Sox (41-63) on Friday at Guaranteed Rate Field. First pitch is scheduled for 7:10 p.m. ET. Let’s analyze BetMGM Sportsbook’s lines around the Guardians vs. White Sox odds and make our expert MLB picks and predictions for the best bets.

Season series: White Sox lead 4-3

The Guardians secured a 6-3 victory over the White Sox on Thursday, with 6 of their batters recording multiple hits. Cleveland is on a 3-game winning streak and is only 1 1/2 games behind the Minnesota Twins atop the AL Central.

In Thursday’s 3-run loss to the Guardians, 2B Jake Burger was responsible for all 3 runs as he launched 2 HRs. Chicago has lost 6 consecutive contests and is in 4th place in the AL Central race, 13 games back.

The Guardians are expected to start RHP Xzavion Curry on Friday.

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Guardians at White Sox projected starters

RHP Xzavion Curry vs. RHP Touki Toussaint

Curry (3-0, 2.98 ERA) makes his 3rd start and 27th appearance. The rookie has a 1.16 WHIP, 2.3 BB/9 and 6.3 K/9 in 54 1/3 innings.

  • Last start: No-decision, 3 IP, 1 ER, 1 H, 3 BB, 3 K in an 8-5 home loss to the Philadelphia Phillies on Sunday
  • 2023 road stats: 1-0 with a 3.55 ERA, 1.18 WHIP, and 6.4 K/9 in 25 1/3 IP in 12 appearances (1 start)
  • Career vs. White Sox: 0-0 with a 2.08 ERA, 1.39 WHIP, and 10.4 K/9 in 4 1/3 IP in 3 appearances

Toussaint (0-3, 4.06 ERA) makes his 5th start and 9th appearance. He has a 1.32 WHIP, 6.4 BB/9 and 7.3 K/9 in 31 innings.

  • Last start: Loss, 6 IP, 5 ER, 4 H, 4 BB, 3 K in a 5-1 road loss against the New York Mets on July 19.
  • 2023 home stats: 0-1 with a 1.80 ERA, 0.80 WHIP, and 8.1 K/9 in 10 IP in 3 appearances (1 start).
  • Career vs. Guardians: 0-0 in 1 start with a 47.25 ERA, 5.25 WHIP, and 13.5 K/9 in 1 1/3 IP

Guardians at White Sox odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 9:30 a.m. ET.

  • Moneyline (ML): Guardians -145 (bet $145 to win $100) | White Sox +120 (bet $100 to win $120)
  • Run line (RL)/Against the spread (ATS): Guardians -1.5 (+105) | White Sox +1.5 (-125)
  • Over/Under (O/U): 10 (O: -110 | U: -110)

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Guardians at White Sox picks and predictions

Prediction

Guardians 6, White Sox 3

Moneyline

BET GUARDIANS (-145).

The White Sox are looking to offload players ahead of the trade deadline and they’ve lost 8 of their last 10 contests. Meanwhile, the Guardians are 7-3 in their last 10 games and have their sights on trying to win the AL Central.

Run line/Against the spread

With Toussaint pitching for the White Sox, GUARDIANS -1.5 (+105) is my bet. Cleveland has won by at least 2 runs in 6 of its last 7 victories.

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Over/Under

UNDER 10 (-110) is the pick with it being a high total. Curry has pitched well as an opener for the Guardians and the White Sox have tallied fewer than 5 runs in 6 of their last 8 games.

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