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The Chicago White Sox (30-97) and San Francisco Giants (65-63) wrap up a 3-game series Wednesday. First pitch from Oracle Park is set for 3:45 p.m. ET. Let’s analyze FanDuel Sportsbook’s lines around the White Sox vs. Giants odds and make our expert MLB picks and predictions for the best bets.
Season series: Giants lead 2-0
The White Sox look to avoid an interleague series sweep after suffering a 4-1 loss as +212 underdogs Tuesday as the Under (7.5) cashed. The Giants have outscored the ChiSox 9-4 in the first 2 games of the series, and the Chicago offense has been limited to just 5 runs in the past 4 games for a 1.25 runs per game (RPG) average. It’s no surprise the Under is 3-0-1 in that span.
The Giants have rattled off 3 consecutive wins to get above the .500 mark, while allowing just 8 runs in the previous 5 outings for a 1.6 RPG average. Like Chicago, the Under is 3-0-1 in San Francisco’s past 4 contests.
Chicago heads into this game just 12-53 on the road, while posting a league-worst minus-263 run differential. The ChiSox are also an MLB-worst 10-29 in interleague play.
San Francisco has managed a 38-27 record at home, while going 17-19 against the American League.
White Sox at Giants projected starters
LHP Garrett Crochet vs. RHP Logan Webb
Crochet (6-9, 3.61 ERA) makes his 26th start. He has a 1.07 WHIP, 2.2 BB/9 and 12.7 K/9 in 124 2/3 innings.
- Last start: No-decision, 4 IP, 1 ER, 4 H, 0 BB, 9 K in 5-4 win at Houston Astros Friday
- 2024 road splits: 2-3, 3.91 ERA (53 IP, 23 ER), 1.09 WHIP, .205 opponents’ batting average (OBA), 8 HR, 11.5 K/9 in 11 starts
- Has never faced Giants
Webb (11-8, 3.17 ERA) makes his 26th start. He has a 1.22 WHIP, 2.2 BB/9 and 7.7 K/9 in 164 2/3 innings.
- Last start: Win, 7 2/3 IP, 0 ER, 4 H, 1 BB, 7 K in 6-0 home shutout of Atlanta Braves Thursday
- 2024 home splits: 7-3, 2.26 ERA (83 2/3 IP, 21 ER), 1.00 WHIP, .223 OBA, 1 complete game, 3 HR, 7.0 K/9, in 12 starts
- Career vs. White Sox: 0-2, 5.73 ERA (11 IP, 7 ER), 1.45 WHIP, 1 BB, 9 K in 2 starts
Who’s going yard? Here’s a breakdown of today’s best home run props with our top picks. Include the BetMGM bonus code SBWIRE to scor5e a $1,500 first-bet offer.
White Sox at Giants odds
Provided by FanDuel Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 2:59 a.m. ET.
- Moneyline (ML): White Sox +190 (bet $100 to win $190) | Giants -230 (bet $230 to win $100)
- Run line (RL)/Against the spread (ATS): White Sox +1.5 (-118) | Giants -1.5 (-102)
- Over/Under (O/U): 7 (O: -110 | U: -110)
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White Sox at Giants picks and predictions
Prediction
Giants 4, White Sox 2
Moneyline
The Giants (-230) will cost 2.3 times the potential return. That’s quite risky … even against a 97-loss team.
San Francisco covered the run line in the first 2 games of this series, winning each contest by 2 or more runs as the favorite. However, there is still plenty of risk.
PASS and look to the favorite on the run line instead.
Run line/Against the spread
The GIANTS -1.5 (-102) are a solid play as favorites, although be careful, as Crochet is easily the best White Sox starting pitcher.
It isn’t going to be easy, but once San Francisco gets to the Chicago bullpen, the Giants should have enough offense to pull ahead by at least 2 runs to complete the series sweep.
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Over/Under
UNDER 7 (-110) is the lean but only for a half-unit play to be on the safe side.
We’ve seen the Under go 1-0-1 in the first 2 games of this series, with Chicago averaging 2.0 RPG and San Francisco scoring 4.5 RPG. If this finale follows along the same lines, we’ll get another Under result, even if just barely.
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