Chicago White Sox at San Francisco Giants odds, picks and predictions

Analyzing Tuesday’s Chicago White Sox at San Francisco Giants odds and lines, with MLB expert picks, predictions and best bets.

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The Chicago White Sox (30-96) and San Francisco Giants (64-63) play the middle contest of a 3-game series Tuesday. First pitch from Oracle Park is set for 9:45 p.m. ET (MLB Network). Let’s analyze FanDuel Sportsbook’s lines around the White Sox vs. Giants odds and make our expert MLB picks and predictions for the best bets.

Season series: Giants lead 1-0

The White Sox dropped the interleague series opener 5-3 on Monday night, the team’s 3rd consecutive setback. Chicago, already eliminated from the playoffs, is just 4 losses away from hitting 100 for the 2nd straight season.

With Monday’s loss, Chicago is now just 12-52 on the road, while going 10-28 in interleague play. Facing southpaws has been a chore, too, as the White Sox are just 6-19 against left-handed starting pitchers.

The Giants have won 3 of the past 4 outings, outscoring the opposition 15-7. The Under is 3-0-1 in that span, while going 5-1-1 in the past 7 outings.

San Francisco is 16-19 in interleague play, but 45-40 against a right-handed starting pitcher. The Giants are 37-27 at home, too.

White Sox at Giants projected starters

RHP Davis Martin vs. LHP Robbie Ray

Martin (0-1, 3.00 ERA) makes his 4th start and 5th appearance. He has a 1.39 WHIP, 5.0 BB/9 and 8.5 K/9 in 18 IP.

  • Last start: No-decision, 5 2/3 IP, 1 ER, 4 H (solo HR), 3 BB, 5 K in 10-2 home setback vs. New York Yankees last Wednesday
  • 2024 road splits: 0-1, 3.72 ERA (9 2/3 IP, 4 ER), 1.24 WHIP, .229 opponents’ batting average (OBA), 4 BB, 9 K in 2 starts
  • Has never faced Giants

Ray (2-2, 6.00 ERA) makes his 6th start. He has a 1.33 WHIP, 5.1 BB/9 and 12.9 K/9 in 21 IP.

  • Last start: Loss, 2/3 IP, 5 ER, 1 H (1 HR), 3 BB, 2 K in 13-2 home loss vs. Atlanta Braves last Wednesday
  • 2024 home splits: 0-2, 9.00 ERA (11 IP, 11 ER), 2.00 WHIP, .317 OBA, 4 HR, 9 BB, 13 K in 3 starts
  • Career vs. White Sox: 0-1, 3.66 ERA (19 2/3 IP, 8 ER), 3 BB, 31 K in 3 starts

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White Sox at Giants odds

Provided by FanDuel Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 9:34 a.m. ET.

  • Moneyline (ML): White Sox +215 (bet $100 to win $215) | Giants -260 (bet $260 to win $100)
  • Run line (RL)/Against the spread (ATS): White Sox +1.5 (+100) | Giants -1.5 (+120)
  • Over/Under (O/U): 7.5 (O: -128 | U: +104)

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White Sox at Giants picks and predictions

Prediction

Giants 6, White Sox 2

Moneyline

The Giants (-260) will cost you more than 2 1/2 times your potential return, and that’s way too much risk for standalone wager, even if the White Sox (+215) are a horrific team which loses more than 3 times the amount of games they win.

PASS, and look to the run line instead.

Run line/Against the spread

The GIANTS -1.5 (+120) are a much better play at plus-money on the run line.

San Francisco barely covered 5-3 in Monday’s series opener, but Matt Chapman’s homer in the 6th inning made a huge difference. San Francisco has won 3 in a row, and each victory has come by 2 or more runs. So, if you like the Giants to win, you should also like them to get the job done on the run line.

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Over/Under

OVER 7.5 (-128) is the lean, but go with a half-unit play at most.

You’ll be going against the trends a bit, as the Under is 4-1-1 in the past 6 games for San Francisco. However, the Over is 3-2 in Ray’s 5 starts with the Giants so far this season.

For the White Sox, the Under is 2-0-1 in the past 3 outings, but the White Sox have allowed 27 runs in the past 5 contests, or 5.4 runs per game. Look for San Francisco to do most of the heavy lifting.

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You may love betting on sports, but until college football and the NFL seasons officially start, the pickings can get slim. You can fill some of that time and scratch that itch at online casinos and enjoy slots, blackjack, video poker and more.

For more sports betting picks and tips, check out SportsbookWire.com and BetFTW.

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