Chicago White Sox at Houston Astros odds, picks and predictions

Analyzing Sunday’s Chicago White Sox at Houston Astros odds and lines, with MLB expert picks, predictions and best bets.

The Chicago White Sox (1-2) and Houston Astros (2-1) meet Sunday for the final game of their opening 4-game set. First pitch from Minute Maid Park is set for 2:10 p.m. ET. Let’s analyze BetMGM Sportsbook’s lines around the White Sox vs. Astros odds and make our expert MLB picks and predictions for the best bets.

Season series: Astros lead 2-1

After Chicago took the opener 3-2, thanks to 1B Andrew Vaughn’s 9th-inning, tiebreaking, 2-run double, Houston won the next 2 games, 6-3 Friday and 6-4 Saturday.

LF Yordan Alvarez’s base-clearing double did the damage in Friday’s win for Houston, while RF Kyle Tucker’s 7th-inning, RBI single broke a 3-3 tie in Saturday’s victory.

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White Sox at Astros projected starters

RHP Mike Clevinger vs. RHP Luis Garcia

Clevinger went 7-7 in 2022 with a 4.33 ERA (114 1/3 IP, 55 ER), 1.20 WHIP, 7.2 K/9 and 2.8 BB/9 in 22 starts and 1 relief appearance for the Padres.

  • Was mediocre on the road last season with a 4-4 record and 5.46 ERA (64 1/3 IP, 39 ER) with 11 HR allowed and 23 BB.
  • Making his White Sox debut after signing as a free agent in December.

Garcia went 15-8 with a 3.72 ERA (157 1/3 IP, 65 ER), 1.13 WHIP, 9.0 K/9 and 2.7 BB/9 in 28 starts last season.

  • Was very good at home with an 11-3 record but had a 4.46 ERA (84 /23 IP, 43 ER) with 16 HR and 19 BB in 15 starts.
  • Career vs. White Sox: 1-0, 3.00 ERA (12 IP, 4 ER) in 2 starts, including a 21-5 victory at Chicago last August.

White Sox at Astros odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 2:57 a.m. ET.

  • Moneyline (ML): White Sox +140 (bet $100 to win $140) | Astros -165 (bet $165 to win $100)
  • Run line (RL)/Against the spread (ATS): White Sox +1.5 (-140) |  Astros -1.5 (+115)
  • Over/Under (O/U): 8.5 (O: -110 | U: -110)

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White Sox at Astros picks and predictions

Prediction

Astros 4, White Sox 3

Moneyline

BET ASTROS (-165).

The White Sox have been terrible in Houston recently. They are 5-17 in their last 22 games in Houston. Plus, they are also only 11-23 in the last 34 meetings overall while the Astros are 4-0 in Garcias’ last 4 starts overall.

Run line/Against the spread

PASS.

Though I could see a lean to the White Sox +1.5 (-140) as they tend to play the Astros close. Houston only won 4 of the 7 games against Chicago last season.

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Over/Under

LEAN UNDER 8.5 (-110).

In the last 10 White Sox-Astros meetings the Under is 4-5-1. My gut feeling just sees a tight, low-scoring game in the finale. Plus, it’s a get-away day for the White Sox, who fly to Chicago after the game for their Monday home opener.

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