Chicago Cubs at St. Louis Cardinals odds, picks and predictions

Analyzing Friday’s Chicago Cubs at St. Louis Cardinals odds and lines, with MLB expert picks and predictions.

The Chicago Cubs (51-51) and St. Louis Cardinals (46-58) meet Friday for the 2nd contest of a 4-game series in St. Louis. First pitch at Busch Stadium is slated for 8:15 p.m. ET. Let’s analyze BetMGM Sportsbook’s lines around the Cubs vs. Cardinals odds and make our expert MLB picks and predictions for the best bets.

Season series: Cubs lead 6-4

The Cubs won Thursday’s lid-lifter 10-3. They have won 6 in a row and 8 of their last 9.

St. Louis is 2-2 in its last 4, taking 2 of 3 at the Arizona Diamondbacks in the middle of the week. Prior to that series, the Cardinals visited Wrigley Field for a 4-game set. They won the opener, but dropped the final 3 games. So, they have now lost 4 in a row to the rival Cubs.

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Cubs at Cardinals projected starters

TBD vs. LHP Jordan Montgomery

Reports have Cubs RHP Hayden Wesneski (2-3, 4.75 ERA) getting called up from Triple-A Iowa to make his 11th start with the big club this season. He owns a 1.20 WHIP, 2.2 BB/9 and 7.3 K/9 in 60 2/3 innings across 15 appearances.

  • Last pitched for Cubs July 2, working 2 scoreless relief innings; optioned 2 days later to Iowa where he logged a 1.64 ERA, 1.09 WHIP in 11 IP after being sent down
  • 2023 MLB road stats: 1-2, 5.52 ERA (31 IP, 19 ER) in 7 games (6 starts)
  • Career vs. Cardinals: Pitched 2/3 innings June 25, marking his only appearance against the Redbirds (0 ER, 1 H, 1 BB 2 K)

Montgomery (6-8, 3.37 ERA) makes his 21st start. He has a 1.23 WHIP, 2.4 BB/9 and 8.2 K/9 through 115 innings.

  • Last start: Loss, 6 IP, 7 R (5 ER), 6 H, 2 BB, 4 K in 7-2 loss at Cubs Sunday
  • 2023 home stats: 4-3, 3.39 ERA (58 1/3 IP, 22 ER) in 10 starts
  • Last 5 vs. Cubs: 3-2, 3.00 ERA (2022-23)
  • Clocked 1.17 ERA across 5 starts prior to his last (June 20-July 18)

Cubs at Cardinals odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 5:16 p.m. ET.

  • Moneyline: Cubs +120 (bet $100 to win $120) | Cardinals -145 (bet $145 to win $100)
  • Run line (RL)/Against the spread (ATS): Cubs +1.5 (-160) | Cardinals -1.5 (+135)
  • Over/Under (O/U): 9 (O: -120 | U: +100)

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Cubs at Cardinals picks and predictions

Prediction

Cubs 6, Cardinals 5

Moneyline

At 4.96 runs per game and 4.42 run per game allowed, the Cubs are deserving of a better record. Friday’s mound matchup does not put the Cubs’ best foot forward, but Wesneski may be a tad overlooked.

Montgomery figures to be slightly overrated, based both on his season line and in recent turns (.234 batting average on balls in play has buoyed a July ERA of 2.74). Expected-ERA figures peg the southpaw as being due some regression.

While BetMGM offers a Cubs (+120) ML line, look to FanDuel Sportsbook to BET CUBS (+130) at a tag with better leverage.

Run line/Against the spread

Avoid the extra juice here. PASS.

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Over/Under

The Montgomery fade and Cubs starter situation makes for an OVER 9 (-120) play. Mix in 2 second-division bullpens, some potential fatigue at the back end of the Cubs ‘pen, and a sultry St. Louis evening with an outward breeze in the forecast.

BET OVER 9 (-120).

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