Chicago Cubs at St. Louis Cardinals Game 2 odds, picks and predictions

Analyzing Thursday’s Chicago Cubs at St. Louis Cardinals odds and lines, with MLB expert picks and predictions.

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The Chicago Cubs (41-61) and St. Louis Cardinals (55-48) end their 3-game series at Busch Stadium with the second game of a doubleheader Thursday. First pitch for the nightcap is slated for 7:45 p.m. ET. Let’s analyze Tipico Sportsbook‘s lines around the Cubs vs. Cardinals odds with MLB picks and predictions.

(Stats don’t include Thursday’s first game of the doubleheader).

Season series: Cardinals lead 5-4

Wednesday’s game was postponed due to weather, giving both teams a night off. Unfortunately for both clubs, they struggle after a day of rest – the Cubs are 3-9 after a day off; the Cards are 5-8.

The Cubs come into Thursday’s doubleheader scoreless in their past 2 games. While the Cubs are out of playoff contention, the Cardinals are 1½ games behind the NL Central-leading Milwaukee Brewers.

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Cubs at Cardinals projected starters

LHP Sean Newcomb vs. LHP Jose Quintana

Newcomb (0-0, 11.57 ERA) will make his 1st start and 8th appearance this season. He pitched 3 games for the Atlanta Braves before being traded to Chicago April 21. Between the 2 clubs, he owns a 2.36 WHIP, 5.8 BB/9 and 7.7 K/9 in 9 1/3 IP.

  • 16.62 ERA (4 1/3 IP, 8 ER, 4 games) since traded to Cubs
  • Allows 1.32 OPS in away games this year

Quintana (3-5, 3.50 ERA) will make his 21st start of the year. He has a 1.27 WHIP, 2.7 BB/9 and 7.8 K/9 in 103 IP.

  • 3.67 ERA (27 IP, 11 ER, 5 games) in July
  • Last start: No-decision, 5 2/3 IP, 0 ER, 4 H, 2 BB, 4 K in 4-2 home loss to Philadelphia Phillies Friday

Cubs at Cardinals odds and lines

Odds provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 3:44 p.m. ET.

  • Money line (ML): Cubs +140 (bet $100 to win $140) | Cardinals -175 (bet $175 to win $100)
  • Run line (RL)/Against the spread (ATS): Cubs +1.5 (-150) | Cardinals -1.5 (+122)
  • Over/Under (O/U): 8.5 (O: -102 | U: -122)

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Cubs at Cardinals picks and predictions

Prediction

Cardinals 6, Cubs 4

Money line

The Cardinals are 3-0 in the 2nd game of a doubleheader this season. The Cubs, on the other hand, are 0-4.

The Cardinals are 4th in the NL in batting average (.252) and should come out swinging before their next series, a 3-game home set with the New York Yankees.

LEAN CARDINALS (-175)

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Run line/Against the spread

In his 3 wins this season, Quintana has allowed just 1 run. With the Cubs most likely treating the nightcap as a bullpen game, the Cardinals have a great matchup, especially since relief pitching was the only position the Cubs sold off at the trade deadline.

With the Cardinals a perfect 3-0 ATS in the 2nd game of a doubleheader, LEAN CARDINALS -1.5 (+122).

Over/Under

In the final game of a doubleheader, both the Cubs (2-1-1 O/U) and Cardinals (2-1 O/U) hit the Over 66.7% of the time despite their recent trend toward the Unders – the Cubs are 1-7 O/U in their last 8 games overall; the Cards are 2-6 O/U in their last 8.

LEAN OVER 8.5 (-102).

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