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The Chicago Cubs (7-4) and San Diego Padres (6-8) meet Wednesday in the finale of a 3-game series. First pitch from Petco Park is set for 6:40 p.m. ET. Let’s analyze BetMGM Sportsbook’s lines around the Cubs vs. Padres odds and make our expert MLB picks and predictions for the best bets.
Season series: Tied 1-1
The Cubs beat the Padres 5-1 on Tuesday while covering as +124 road underdogs. Chicago scored all 5 of its runs in the 5th inning of a 0-0 game and all 5 runs came via HRs: a solo shot from C Yan Gomes, followed by a grand slam from 3B Christopher Morel.
Padres RHP Joe Musgrove took the loss with 4 IP, 5 H, 4 ER, 3 BB and 5 K. The Padres have not strung together back-to-back wins since March 28.
Cubs at Padres projected starters
RHP Kyle Hendricks vs. RHP Dylan Cease
Hendricks (0-1, 11.74 ERA) makes his 3rd start. He has a 2.74 WHIP, 4.7 BB/9 and 7.0 K/9 in 7 2/3 IP.
- Has had a rough start to the year, allowing 17 H, 10 ER with only 6 K in 2 starts
- Career vs. San Diego: 8-3, 2.74 ERA (88 2/3 IP, 27 ER), 69 H, 10 BB, 82 K in 14 starts
Cease (0-1, 3.38 ERA) makes his 3rd start. He has a 0.94 WHIP, 3.4 BB/9 and 11 K/9 in 10 2/3 IP.
- Last start: No-decision, 6 IP, 4 H, 2 ER, 2 BB, 7 K in a 3-2 loss Friday vs. the San Francisco Giants
- Career vs. Cubs: 2-2, 3.45 ERA (28 2/3 IP, 11 ER), 20 H, 14 BB, 36 K in 5 starts
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Cubs at Padres odds
Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 5:55 a.m. ET.
- Moneyline (ML): Cubs +120 (bet $100 to win $120) | Padres -145 (bet $145 to win $100)
- Run line (RL)/Against the spread (ATS): Cubs +1.5 (-165) | Padres -1.5 (+140)
- Over/Under (O/U): 8 (O: -115 | U: -105)
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Cubs at Padres picks and predictions
Prediction
Cubs 4, Padres 2
Moneyline
PASS.
This is a very tough game to be confident in either squad as they’re 5-5 in their last 10 meetings. Chicago has been the hotter team to start the season, and Hendricks has been very good in his career vs. the Padres, so they would be my lean here. However, I prefer Chicago’s odds on the run line.
Run line/Against the spread
BET CUBS +1.5 (-165).
Chicago has covered the spread in each of its last 3 games and is 4-1 ATS in its last 5. The Cubs are also 8-3 ATS this season. Chicago has covered ATS in back-to-back matchups vs. San Diego and is 5-2 ATS in the last 7 meetings.
Over/Under
LEAN UNDER 8.5 (-105).
The Under has hit in 6 of San Diego’s last 7 overall and is 3-1 in its last 4 home games. The Under has also hit in 9 of the last 10 Cubs-Padres meetings and is 5-1 in the last 6 meetings in San Diego.
This is only a lean because the Over is 7-4 for Chicago this season and the Padres are 6-7-1 O/U.
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