Chicago Cubs at Arizona Diamondbacks odds, picks and predictions

Analyzing Tuesday’s Chicago Cubs at Arizona Diamondbacks odds and lines, with MLB expert picks, predictions and best bets.

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The Chicago Cubs (10-6) and Arizona Diamondbacks (8-9) play the 2nd game of a 3-game series at Chase Field Tuesday. First pitch is scheduled for 9:40 p.m. ET. Let’s analyze BetMGM Sportsbook’s lines around the Cubs vs. Diamondbacks odds and make our expert MLB picks and predictions for the best bets.

Season series: Cubs lead 1-0

The Cubs took Monday’s opener 3-2 in 11 innings after 2B Nico Hoerner tied it up in the 9th by scoring from 2nd base on a wild pitch. It was their 3rd straight win.

The Diamondbacks have won 4 of their last 6 games but are 4-7 in their last 11.

Cubs at Diamondbacks projected starters

RHP Kyle Hendricks vs. LHP Tommy Henry

Hendricks (0-2, 12.08 ERA) makes his 4th start. He has a 2.37 WHIP, 4 BB and 8 K in 12 2/3 innings.

  • Last start: Loss, 5 IP, 7 ER, 9 H, 0 BB, 2 K in 10-2 road loss to San Diego Padres Wednesday
  • Has allowed 5+ ER in all 3 starts this season

Henry (0-1, 5.79 ERA) makes his 4th start. He has a 1.64 WHIP, 7 BB and 15 K in 14 innings.

  • Last start: No-decision, 5 IP, 3 R (2 ER), 3 H, 3 BB, 6 K in 5-3 road win over Colorado Rockies Wednesday
  • Making 1st career appearance vs. Cubs

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Cubs at Diamondbacks odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 9:20 a.m. ET.

  • Moneyline (ML): Cubs +105 (bet $100 to win $105) | Diamondbacks -125 (bet $125 to win $100)
  • Run line (RL)/Against the spread (ATS): Cubs +1.5 (-185) | Diamondbacks -1.5 (+150)
  • Over/Under (O/U): 10 (O: -115 | U: -105)

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Cubs at Diamondbacks picks and predictions

Prediction

Diamondbacks 8, Cubs 5

Moneyline

The Diamondbacks (-125) have not lost consecutive games at home yet this season. They have lost the opener in their last 2 series and then won the next 2 games.

Hendricks has struggled in all 3 starts he has made. Henry has allowed 2 ER in each of his last 2 starts.

Arizona has won 7 of the last 10 meetings against the Cubs (+105).

But because they usually win by multiple runs, it’s better to go with the run line.

PASS.

Run line/Against the spread

Arizona has won by 2 or more runs in 7 of their 8 victories.

Four of the Cubs’ 6 losses have been by 2 or more runs.

You have to like the plus odds for the Diamondbacks to cover here, especially with how Henry has pitched to start the season.

BET DIAMONDBACKS -1.5 (+150).

Over/Under

All 3 of Hendricks’ starts have had totals of 12 runs or more. He himself has allowed 5 or more in his starts.

Two of Henry’s 3 starts have had more than 10 runs as the total.

The Diamondbacks have played in 8 games this season with totals of 10 or more.

BET OVER 10 (-115).

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