Betting the NFL Line: Week 10

A league-wide view into the best wagers to make for NFL Week 10 action.

The demarcation between the good teams, struggling teams, and bad teams is playing itself out this week for those looking to wager on point spreads.

Only three of the 14 games have a current point spread of three points or fewer on the Week 10 slate, while six games have a spread of 6.5 points or more.

Numbers like scream that could be a lot of blowouts this week … or at least the perception that beat-downs are coming is clear.


Odds provided by BetMGM Sportsbook


Cincinnati Bengals (+220) at Baltimore Ravens (-275)

The Ravens are big favorites (6.5 points at -120 Bengals, -110 Ravens). Divisional games between playoff-hardened teams is rarely this high, but Baltimore is clicking – winning their last four games and seven of nine games this year by eight points or more. Take the Ravens and lay 6.5 points (-110).


New York Giants (-275) at Carolina Panthers (+220)

The Over/Under is low (40.5 points at -115 Over, -105 Under). There is a reason. Both teams have hit Under this number in six of their nine games. They play field-position games that have field goals deciding them. Take Under 40.5 points (-105).


New England Patriots (+230) at Chicago Bears (-275)

The Bears are strong home favorites (6.5 points at -110 for both teams). The Patriots are in rebuild mode and that shows up on the road. Their last four losses included deficits of 21, 17, and 16 points. Take the Bears and lay 6.5 points (-110).


Buffalo Bills (-210) at Indianapolis Colts (+170)

The Bills are road favorites (4 points at -110 for both teams). The Colts are teetering on irrelevance, while the Bills are looking to stay with the other AFC big dogs. Buffalo has scored 30 or more points in six of nine games and the Colts aren’t equipped to compete with that. Take the Bills and lay 4 points (-110).


Denver Broncos (+310) at Kansas City Chiefs (-400)

Once again, the Chiefs are big favorites (8.5 points at -110 for both teams). We’ve been down this road before. The Chiefs win, but they don’t cover because their number is too high. I’ve taken the bait before. I am again. Take the Chiefs and lay 8.5 points (-110).


Atlanta Falcons (-200) at New Orleans Saints (+165)

The Falcons are decent road favorites (3.5 points at -115 Falcons, -105 Saints). The Saints fired their head coach, and the Falcons have won five of the last six. Don’t buy into the “new coach bump” routine here. Take the Falcons and lay 3.5 points (-115).


San Francisco 49ers (-250) at Tampa Bay Buccaneers (+200)

The Chiefs are stiff road favorites (5.5 points at -110 for both teams). The Bucs are likely without their top two receivers on a short week after going five quarters against the Chiefs, and Christian McCaffrey may be back. Take the 49ers and lay 5.5 points (-110).


Pittsburgh Steelers (+120) at Washington Commanders (-145)

If you at the hindsight strength of the opponents both teams have played, there hasn’t been a “signature win” among any of them. The Steelers defense is legit and make plays against those who take risks. Jayden Daniels takes risks. Take the Steelers on the moneyline (+120).


Minnesota Vikings (-225) at Jacksonville Jaguars (+185)

The Vikings are an impressive road favorite (4.5 points at -110 for both teams). Minnesota still needs to make some believers, and the banged-up Jaguars are starting to book January vacation destinations. Take the Vikings and lay 4.5 points (-110).

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Tennessee Titans (+300) at Los Angeles Chargers (-375)

The Chargers are prohibitive favorites (7.5 points at -105 Titans, -115 Chargers). In all six Tennessee losses, the Titans have scored 17 or fewer points. The Chargers’ five wins have come by 12, 23, 7, 18, and 7 points. Those are a good combination. Take the Chargers and lay 7.5 points (-115).


Philadelphia Eagles (-350) at Dallas Cowboys (+280)

The Eagles are huge road favorites (7.5 points at -105 Eagles, -115 Cowboys). These may be the most overrated teams in the league. Dak Prescott is out, but it’s hard to give a home team on the brink of disaster more than a TD cushion at home. Take the Cowboys plus 7.5 points (-115).


New York Jets (-110) at Arizona Cardinals (-110)

The Cardinals are favored by only one point at home. The Jets are on life support, so they will take more risks. Aaron Rodgers in a death match works here, because one more loss kills their season. Take the Jets on the moneyline (-110).


Detroit Lions (-190) at Houston Texans (+155)

Detroit is a road favorite (3.5 points at -110 for both teams). The Lions are not only beating people, they’re beating up people. The Texans are a good team but can’t trade punches with a heavyweight from Detroit. Take the Lions and lay 3.5 points (-110).


Miami Dolphins (+100) at Los Angeles Rams (-120)

The Over/Under is huge (50 points at -110 for both Over and Under). It took until Week 10 for both teams to have all their star offensive players together on the same field, and they’re going let it fly under the primetime lights. Take Over 50 points (-110).