Baltimore Orioles at San Diego Padres odds, picks and predictions

Analyzing Monday’s Baltimore Orioles at San Diego Padres odds and lines, with MLB expert picks, predictions and best bets.

The Baltimore Orioles (73-45) continue their 9-game road trip with the opening game of a 3-game series on Monday against the San Diego Padres (56-62). First pitch from Petco Park is at 9:40 p.m. ET. Let’s analyze BetMGM Sportsbook’s lines around the Orioles vs. Padres odds and make our expert MLB picks and predictions for the best bets.

Season series: First meeting since Padres took 3 of 4 games in 2019

The Orioles lead the AL East by 3 games and have the best record in the American League. They won the last 2 games in their series against the Seattle Mariners and 10-4 in their last 14 games.

The Padres have lost 2 in a row and are coming off a 1-4 road trip. They have lost 6 of their last 7 games.

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Orioles at Padres projected starters

RHP Grayson Rodriguez vs. RHP Yu Darvish

Rodriguez (2-3, 5.84 ERA) makes his 16th start. He has a 1.49 WHIP, 3.8 BB/9 and 9.7 K/9 in 74 innings.

  • Last start: No-decision, 6 IP, 2 ER, 6 H, 2 BB, 4 K in 7-6 home loss to Houston Astros on Tuesday
  • Orioles 2-4 in his last 6 outings

Darvish (8-7, 4.19 ERA) makes his 22nd start. He has a 1.26 WHIP, 3.0 BB/9 and 9.3 K/9 in 120 1/3 innings.

  • Last start: No-decision, 6 IP, 1 R (0 ER), 6 H, 2 BB, 4 K in 6-1 road loss to Seattle Mariners on Wednesday
  • Has allowed 2 or fewer runs in 4 of last 5 starts

Orioles at Padres odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 8:47 a.m. ET.

  • Moneyline (ML): Orioles +120 (bet $100 to win $120) | Padres -145 (bet $145 to win $100)
  • Run line (RL)/Against the spread (ATS): Orioles +1.5 (-175) | Padres -1.5 (+145)
  • Over/Under (O/U): 8.5 (O: +100 | U: -120)

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Orioles at Padres picks and predictions

Prediction

Orioles 5, Padres 4

Moneyline

The pitching matchup is to the Padres’ advantage, but the Orioles have a 37-22 road record this season and have won 5 of their last 7 road games and 10 of their last 14 games overall. The Padres are only 30-28 at home and have lost 6 of their last 7 games.

It is odd that Baltimore is an underdog, but take advantage of the plus odds.

BET ORIOLES (+120).

Run line/Against the spread

The Orioles are 73-45 ATS this season, the 2nd-best mark in MLB. They are 42-16 ATS as the underdog while the Padres are 42-48 ATS as the favorite.

In 6 of the last 7 games the Orioles have covered the spread as the underdog, they have won outright.

PASS.

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Over/Under

Eight of the Padres’ last 11 games have had 9 or more total runs whil 6 of the Orioles’ last 9 have had 9 or more runs.

Six of the last 8 starts for Rodriguez have had 9 or more total runs and 4 of Darvish’s last 7 starts have had 9 or more runs.

BET OVER 8.5 (+100).

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For more sports betting picks and tips, check out SportsbookWire.com and BetFTW.

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