Baltimore Orioles at New York Yankees odds, picks and best bets

Previewing Friday’s Baltimore Orioles at New York Yankees sports betting odds and lines, with MLB betting picks, tips and best bets.

The Baltimore Orioles (20-22) and New York Yankees (22-21) play the first game of a Friday doubleheader at Yankee Stadium at 4:05 p.m. ET. We analyze the Orioles-Yankees MLB betting odds and lines, with picks and best bets.

Orioles at Yankees: Projected starting pitchers

RHP Alex Cobb vs. RHP Gerrit Cole

Cobb has posted a 1-3 record, 4.33 ERA and 1.33 WHIP with 24 strikeouts across 35 1/3 innings over 7 starts this season.

  • Cobb allowed five runs – four earned – and eight hits with two walks and two strikeouts in just four innings in a loss against the Toronto Blue Jays in Buffalo Aug. 29 in his most recent outing.
  • The good news from Cobb’s last start, his streak of four straight outings allowing a home run came to an end. He has served up a homer in five of his seven starts this season.

Also see: BaseballHQ Fantasy Baseball

Cole has been rather mediocre this season, going just 4-3 with a 3.63 ERA and 1.10 WHIP with 70 strikeouts across 52 innings in his nine starts. Cole is tied for fifth in the majors in strikeouts.

  • Cole allowed five runs – one earned – and four hits with two walks and a season-high-tying 10 strikeouts over six innings in a loss in Baltimore Sept. 5 in his most recent outing.
  • Cole is 1-1 with a 2.84 ERA with 17 strikeouts over 12 2/3 innings in two starts vs. Baltimore this season. He also has a .170 opponent batting average against the O’s in 2020.

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Orioles at Yankees: Key injuries

(List of injuries around the league)

Yankees

  • OF Aaron Judge (calf) out
  • OF Giancarlo Stanton (hamstring) out
  • 3B Gio Urshela (elbow) out

Orioles at Yankees: Odds, lines, picks and betting tips

MLB odds courtesy of BetMGM; access USA TODAY Sports for a full list. Odds last updated at 10:30 a.m. ET.

Prediction

Yankees 5, Orioles 2

Moneyline (ML)

The Yankees (-250) enter the day a game and a half up on the Orioles (+125) for the eighth postseason seed in the American League. The O’s are trying to reel in the high-priced Yankees and did a good job with winning three of four last weekend in Charm City, including the final three contests. New York is just too expensive on the moneyline. AVOID.

New to sports betting? A winning $10 bet on New York returns a profit of $4, while a $10 wager on Baltimore nets a profit of $12.50 if it wins.

Run line/Against the spread (ATS)

The YANKEES (-1.5, -110) are a good bet at home, even if they are just 3-3 against the Orioles (+1.5, -110) this season. Cole will earn his huge paycheck in this one.

Over/Under (O/U)

OVER (6.5, -110) is 4-2 in the six previous meetings in this series. Baltimore has been surprisingly effective offensively, averaging 4.98 runs per game to check in eighth in the majors, and the O’s are fifth in team batting average at .267.

Their biggest struggles come on defense, as they have committed 27 errors to rank 21st defensively. The Yankees have posted 4.70 runs per game to rank 16th.

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