Baltimore Orioles at Cleveland Guardians odds, picks and predictions

Analyzing Thursday’s Baltimore Orioles at Cleveland Guardians odds and lines, with MLB expert picks, predictions and best bets.

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The Baltimore Orioles (95-57) and Cleveland Guardians (72-81) start a 4-game series Thursday with 1st pitch from Progressive Field at 7:15 p.m. ET (FOX). Let’s analyze BetMGM Sportsbook’s lines around the Orioles vs. Guardians odds and make our expert MLB picks and predictions for the best bets.

Season series: Guardians lead 2-1

The Orioles had their 4-game win streak snapped on Wednesday in 2-1 loss to the Houston Astros. They look to make it 6 straight road series victories when they travel to Cleveland this weekend. Baltimore currently sits 2 1/2 games ahead of the Tampa Bay Rays in the AL East.

Cleveland returns home after being swept by the Royals in Kansas City. They allowed at least 6 runs in each of those games. The Guardians begin a 7-game homestand where they are 39-36 on the season.

Orioles at Guardians projected starters

RHP Grayson Rodriguez vs. TBD

Rodriguez (6-4, 4.53 ERA) makes his 22nd start. The rookie has a 1.34 WHIP, 3.2 BB/9 and 9.5 K/9 in 111 1/3 innings.

  • Last start: Win, 8 IP, 0 ER, 5 H, 0 BB, 7 K in 8-0 home victory against the Tampa Bay Rays
  • 2023 road stats: 3-2, 4.13 ERA (52 1/3 IP, 24 ER), .240 OBA over 10 starts
  • Never faced the Guardians as a starter

When the article was published, the Guardians had not named a starter

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Orioles at Guardians odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Thursday at 10:55 a.m. ET.

  • Moneyline (ML): Orioles -185 (bet $185 to win $100) | Guardians +150 (bet $100 to win $150)
  • Run line (RL)/Against the spread (ATS): Orioles -1.5 (-110) | Guardians +1.5 (-110)
  • Over/Under (O/U): 8.5 (O: -105 | U: +115)

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Orioles at Guardians picks and predictions

Prediction

Orioles 7, Guardians 3

Moneyline

PASS.

The Orioles will likely win this game, but I’m not putting up nearly 2 units to win back 1. It’s never a good bet.

Run line/Against the spread

BET ORIOLES -1.5 (-110).

The -110 is not crazy appealing, but I don’t mind taking it in this one.

I believe Rodriguez has figured it out at the big league level. He has the tools to be a dominant starter, but struggled to get a handle on things in the majors. He manhandled the Rays in his last start over 8 innings and they are a much better team than the Guardians.

Over/Under

PASS.

We do not know the starter for the Guardians in this one and that is why I’m going to just avoid this bet completely. I really want to know the starters if I’m even going to look at the total.

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For more sports betting picks and tips, check out SportsbookWire.com and BetFTW.

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