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The Baltimore Orioles (6-4) take on the Boston Red Sox (7-4) Wednesday night at Fenway Park. First pitch is scheduled for 7:10 p.m. ET. Let’s analyze FanDuel Sportsbook’s lines around the Orioles vs. Red Sox odds and make our expert MLB picks and predictions for the best bets.
Season series: Orioles lead 1-0
Baltimore downed the Red Sox 7-1 in Boston’s home opener Tuesday afternoon, cashing as a (-121) moneyline favorite. LF Colton Cowser hit 2 doubles and drove in 4, while RHP Corbin Burnes tossed 6 innings of 1-run ball, striking out 6 in the win.
Boston’s lone run came by way of the long ball as RF Tyler O’Neill blasted his league-leading 6th HR of the season in the 6th inning. RHP Brayan Bello, who had a 6.94 ERA in 10 day-game starts in 2023, surrendered only 1 ER in 5 1/3 IP.
Orioles at Red Sox projected starters
LHP Cole Irvin vs. RHP Kutter Crawford
Irvin (0-1, 7.20 ERA) makes his 2nd start. He allowed 4 ER on 7 H and 2 BB with 3 K in 5 innings in his debut vs. the Kansas City Royals April 2.
- His curveball looked impressive out the gate in his debut; however, he took the loss after allowing runs in the 2nd and 4th innings
- Was better on the road than at home last season; sported a 3.79 away ERA in 38 IP compared to a 5.03 ERA at Camden Yards
Crawford (0-0, 0.84 ERA) makes his 3rd start. He has a 0.84 WHIP, 3.38 BB/9 and 10.13 K/9 in 10 2/3 innings.
- Took the no-decision in Boston’s win at Los Angeles Angels Friday; lost the strike zone in the 5th inning and was pulled after 90 pitches
- Was stronger on the road than at home in 2023; he sported a 6.00 ERA in 57 IP at Fenway Park compared to a 2.49 ERA in 72 1/3 IP away from Boston
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Orioles at Red Sox odds
Provided by FanDuel Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 10:20 a.m. ET.
- Moneyline (ML): Orioles -106 (bet $106 to win $100) | Red Sox -110 (bet $110 to win $100)
- Run line (RL): Orioles -1.5 (+158) | Red Sox +1.5 (-194)
- Over/Under (O/U): 9 (O: -110 | U: -110)
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Orioles at Red Sox picks and predictions
Prediction
Orioles 4, Red Sox 3
Moneyline
BET ORIOLES (-106).
The already strong and youthful O’s offense will receive some more juice as MLB’s top prospect INF Jackson Holliday has been called up. Expect the heart of Baltimore’s lineup, including RF Anthony Santander who is tied for the AL lead in RBIs (11), to produce enough runs to help the Orioles eek out a 2nd straight victory over the Red Sox.
Run line/Against the spread
INCLUDE RED SOX +1.5 (-194) IN A PARLAY.
Too juicy for me, but pairing the RED SOX +1.5 (-194) with the NEW YORK YANKEES (-215) at home against the lowly Miami Marlins pays out a much more enticing +122.
Over/Under
BET UNDER 9 (-110).
Entering Wednesday, no team in the AL has swung at more pitches outside the strike zone (31.0 O-Swing %) than Baltimore, so Crawford could get some help if his location falters once again.
Boston has the 4th-lowest contact percentage (74.2%) in all of MLB, plus the fewest doubles hit, and O’Neill seems to be the only real power threat at the moment.
I’m not expecting either offense to explode, especially since both teams are top 5 in the AL in bullpen ERA.
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