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The San Diego Padres (82-64) and Seattle Mariners (73-72) wrap up a 2-game interleague series Wednesday. First pitch from T-Mobile Park is set for 9:40 p.m. ET (FS1). Let’s analyze FanDuel Sportsbook’s lines around the Padres vs. Mariners odds and make our expert MLB picks and predictions for the best bets.
Season series: Mariners lead 2-1
The Padres registered a 7-3 victory against the Mariners in the interleague opener Tuesday behind RHP Yu Darvish as a slight underdog (+112) as the Over (7) connected.
San Diego has picked up 5 wins in the past 8 outings while going 3-1 in the previous 4 games on the road. It is 18-7 across the past 25 contests away from home.
In interleague play, San Diego has cashed in 4 of the past 5 games while going 11-4 in the previous 15 tries against the American League. The Over has hit in 3 straight while going 10-2-1 in the past 13 tries vs. AL teams.
For the Mariners, despite Tuesday’s setback, Seattle has won 4 of the past 6 outings. The Over has hit in the past 2 games while going 8-3-1 across the past 12.
Against the National League, the M’s are just 5-9 in the past 14 tries, although they’re 14-5 in the past 19 home interleague battles.
Padres at Mariners projected starters
RHP Michael King vs. RHP Bryan Woo
King (12-8, 3.10 ERA) makes his 28th start and 29th appearance. He has a 1.21 WHIP, 3.3 BB/9 and 10.6 K/9 in 156 2/3 IP.
- Last start: Win, 6 IP, 1 ER, 6 H (1 solo HR), 1 BB, 8 K in 5-1 home victory vs. San Francisco Giants Friday
- 2024 road splits: 8-3, 2.86 ERA, 85 IP, 27 ER, 9 HR, 1.18 WHIP, .222 opponents’ batting average (OBA), 30 BB, 83 K in 14 starts (15 appearances)
- Career vs. Mariners: 0-1, 2.08 ERA, 8 2/3 IP, 2 ER, 0 HR, 1.04 WHIP, 13.5 K/9 in 3 appearances (1 start)
Woo (7-2, 2.36 ERA) makes his 19th start. He has a 0.85 WHIP, 0.8 BB/9 and 7.0 K/9 in 99 IP.
- Last start: Win, 6 IP, 2 ER, 6 H, 0 BB, 9 K in 16-3 road victory vs. Oakland A’s Aug. 4
- 2024 home splits: 4-0, 1.50 ERA, 42 IP, 7 ER, 2 HR, 0.67 WHIP, .170 OBA, 3 BB, 35 K in 7 starts
- Has never faced Padres
Who’s going yard? Here’s a breakdown of today’s best home run props with our top picks. Include the BetMGM bonus code SBWIRE to score a $1,500 first-bet offer.
Padres at Mariners odds
Provided by FanDuel Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 3:55 a.m. ET.
- Moneyline (ML): Padres -108 (bet $108 to win $100) | Mariners -108 (bet $108 to win $100)
- Run line (RL)/Against the spread (ATS): Padres -1.5 (+168) | Mariners +1.5 (-205)
- Over/Under (O/U): 6.5 (O: -122 | U: +100)
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Padres at Mariners picks and predictions
Prediction
Mariners 3, Padres 2
Moneyline
The MARINERS (-108) are worth a look in the series finale behind Woo. The Seattle right-handed starter has been nearly untouchable at T-Mobile Park, posting an amazing 4-0 record with a 1.50 ERA in 42 IP across 7 starts.
While Woo’s numbers make the M’s look like a slam-dunk play, King has been solid for the Padres (-108), too, and the odds indicate that this is truly a coin flip. But, based on Woo’s slightly better splits at home than King’s numbers on the road, you have to side with Seattle.
Run line/Against the spread
Mariners +1.5 (-205) is just too expensive on the run line, if you require insurance and perhaps are a little spooked by their loss in Tuesday’s interleague series opener.
However, you can’t risk more than 2 times your potential return. If you like Seattle, just bet it straight up.
PASS.
Over/Under
UNDER 6.5 (+100) is worth a roll of the nice at even-money, as we should have a pitchers’ duel in SoDo.
King has tremendous splits on the road, posting 8 victories and a 2.83 ERA, while Woo has a 4-0 mark with a 1.50 ERA at home this season. Neither of these guys are going to concede much. Go low, and feel confidently in doing so.
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