Chicago White Sox at Kansas City Royals odds, picks and predictions

Analyzing Friday’s Chicago White Sox at Kansas City Royals odds and lines, with MLB expert picks, predictions and best bets.

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The Chicago White Sox (27-71) and Kansas City Royals (52-45) open a 3-game set at Kauffman Stadium Friday. First pitch is scheduled for 8:10 p.m. ET. Let’s analyze BetMGM Sportsbook’s lines around the White Sox vs. Royals odds and make our expert MLB picks and predictions for the best bets.

Season series: Royals lead 6-1

The White Sox were swept by the Pittsburgh Pirates in a 3-game weekend series in Chicago before the All-Star break. They’ve lost 4 games in a row and haven’t won a series since taking 2 of 3 against the Colorado Rockies at Guaranteed Rate Field June 28-30.

The Royals were flat heading into the break, dropping 2 of 3 games at the Boston Red Sox July 12-14. SS Bobby Witt Jr. outperformed expectations at the Home Run Derby, though. After entering tied for the 4th-longest odds to win (+500 at BetMGM Sportsbook), he lost by just 1 HR in the final to Los Angeles Dodgers CF Teoscar Hernández.

White Sox at Royals projected starters

RHP Chris Flexen vs. RHP Michael Wacha

Flexen (2-8, 4.82 ERA) makes his 19th start and 21st appearance. He has a 1.37 WHIP, 3.3 BB/9 and 6.6 K/9 in 97 IP.

  • Last start: Loss, 6 IP, 2 ER, 5 H, 2 BB, 4 K in 6-2 home defeat vs. Pirates Saturday
  • 2024 road stats: 1-3, 4.86 ERA (37 IP, 20 ER), 1.22 WHIP, 7.1 K/9 in 8 appearances (6 starts)
  • 2024 vs. Royals: 0-1, 4.26 ERA (6 1/3 IP, 3 ER), 6 H, 2 BB, 4 K in 1 start, a 3-0 road loss April 6
  • Career vs. Royals: 2-1, 2.25 ERA (20 IP, 5 ER), 1.10 WHIP, 5.4 K/9 in 4 appearances (3 starts)

Wacha (6-6, 3.83 ERA) makes his 17th start. He has a 1.24 WHIP, 2.7 BB/9 and 7.9 K/9 in 89 1/3 IP.

  • Last start: Win, 5 IP, 3 ER (4 R), 7 H, 1 BB, 3 K in 8-5 victory at St. Louis Cardinals July 10
  • 2024 home stats: 3-1, 3.49 ERA (38 2/3 IP, 15 ER), 1.32 WHIP, 7.9 K/9 in 7 starts
  • 2024 vs. White Sox: 1-1, 1.38 ERA (13 IP, 2 ER), 0.69 WHIP, 8.3 K/9 in 2 starts
  • Career vs. White Sox: 3-1, 3.89 ERA (39 1/3 IP, 17 ER), 1.07 WHIP, 9.4 K/9 in 7 starts

Who’s going yard? Here’s a breakdown of today’s best home run props with our top picks. Include the BetMGM bonus code SBWIRE to score a $1,500 first-bet offer.

White Sox at Royals odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 12:03 a.m. ET.

  • Moneyline (ML): White Sox +170 (bet $100 to win $170) | Royals -210 (bet $210 to win $100)
  • Run line (RL)/Against the spread (ATS): White Sox +1.5 (-115) | Royals -1.5 (-105)
  • Over/Under (O/U): 8.5 (O: -120 | U: +100)

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White Sox at Royals picks and predictions

Prediction

Royals 6, White Sox 4

Moneyline

The Royals (-210) have won 6 of 7 against the White Sox this season and have a sizable advantage at starting pitcher Friday. However, it’s hard to beat MLB long term betting into sides that are -190 or higher.

PASS. Bet the run line and/or total instead.

Run line/Against the spread

The Royals are 14-11 as run-line favorites at home this season, good for the 2nd-best record in MLB. The White Sox, on the other hand, have the 2nd-worst record in the majors as run-line underdogs on the road (20-26).

Flexen is the least profitable pitcher in MLB this season, according to OddsShark.com. If you were to bet $100 on White Sox ML every time Flexen started this season, you would be down $1,215. The White Sox have also lost 15 of his 20 appearances this year by 2 or more runs.

Wacha has been trending upwards after losing 4 of his 1st 5 decisions to start the season. He’s won back-to-back starts, and the Royals won both outings by multiple runs.

BET ROYALS -1.5 (-105).

Over/Under

The Royals have the 2nd-best home offense in MLB, averaging 5.16 runs per game, and should bounce back after scoring a total of just 4 runs over their final 2 outings before the break. It also doesn’t hurt that they’re facing Flexen, who has allowed 6 or more runs in 3 of his last 4 road starts.

BET OVER 8.5 (-120).

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