San Diego Padres at Los Angeles Angels odds, picks and predictions

Analyzing Wednesday’s San Diego Padres at Los Angeles Angels odds and lines, with MLB expert picks, predictions and best bets.

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The San Diego Padres (32-32) take on the Los Angeles Angels (23-38) Wednesday in the finale of a 3-game set at Angel Stadium at 9:38 p.m. ET (FS1). Let’s analyze BetMGM Sportsbook’s lines around the Padres vs. Angels odds and make our expert MLB picks and predictions for the best bets.

Season series: Angels lead 2-0

The Padres dropped the ol’ Baby Ruth in the swimming pool, allowing 3 runs in the 7th Tuesday night to eventually fall 4-2. They had runners on 2nd and 3rd with 1 out and only managed to score 1. They’ve now lost 3 straight and trail the Los Angeles Dodgers by 7 games in the NL West.

The Angels snapped a string of 7 losses in 8 games with their 2 wins in consecutive nights. They are just 9-21 at home, and Tuesday’s victory was the first time all season they won consecutive games at home. Angels 2B Luis Rengifo is raking with a .329 BA, 4 HR and 18 RBIs.

Padres at Angels projected starters

RHP Dylan Cease vs. RHP Jose Soriano

Cease (5-4, 3.42 ERA) makes his 13th start. He has a 0.97 WHIP, 2.7 BB/9 and 11.0 K/9 in 71 innings.

  • Last start: No-decision, 5 1/3 IP, 3 ER, 5 H, 1 BB, 5 K in 11-8 victory at Kansas City Royals Friday
  • Last 5 starts vs. Angels: 1-1, 3.46 ERA, 1.19 WHIP, 34 K in 26 IP

Soriano (2-5, 3.86 ERA) makes his 11th start and 13th appearance. He has a 1.22 WHIP, 3.9 BB/9 and 8.3 K/9 in 58 1/3 innings.

  • Last start: No-decision, 6 IP, 4 ER, 7 H, 2 BB, 3 K in 5-4 loss Friday at Seattle Mariners
  • 2024 home/road splits: Home: 0-4, 6.75 ERA, 1.30 WHIP, 9.9 K/9 in 4 starts and 1 relief appearance; Road: 2-1, 2.35 ERA, 1.17 WHIP, 7.5 K/9 in 6 GS and 1 relief appearance
  • Career vs. Padres: 0-0, 9.00 ERA (1 IP, 1 ER), 1 H, 1 BB, 2 K in 1 relief appearance of 5-3 road loss July 5, 2023

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Padres at Angels odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 12:42 p.m. ET.

  • Moneyline (ML): Padres -150 (bet $150 to win $100) | Angels +125 (bet $100 to win $125)
  • Run line (RL)/Against the spread (ATS): Padres -1.5 (+115) | Angels +1.5 (-140)
  • Over/Under (O/U): 8 (O: -105 | U: -115)

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Padres at Angels picks and predictions

Prediction

Padres 6, Angels 3

Moneyline

I love the Padres to avoid the sweep here, and honestly, I expected this ML to be a bit higher. As mentioned, the Halos are terrible at home and just won their first back-to-back games there all year. I do not expect them to complete the sweep.

Take PADRES -150 at a solid price that I expect to be juiced up more before first pitch.

Run line/Against the spread

A prop bet that I love here, is DYLAN CEASE OVER 6.5 K’s (-140). This is at a discount compared to other books. He has been a little inconsistent lately with 7+ K’s in 4 of 7 starts. The Angels are in the top half of the league when it comes to frequent whiffing. Cease had 10 and 11 K’s in his last 2 starts against them. Act now.

Over/Under

The wind is slated to blow out to left-center at 7 mph this evening. The Padres have scored just 3 runs in this series, and I look for the bats to awaken enough to carry the torch. It’s a small total, and I’m going OVER 8 (-105).

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