Boston Red Sox at Baltimore Orioles odds, picks and predictions

Analyzing Monday’s Boston Red Sox at Baltimore Orioles odds and lines, with MLB expert picks, predictions and best bets.

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The Boston Red Sox (27-26) and Baltimore Orioles (33-18) open a 3-game series Monday. First pitch from Oriole Park at Camden Yards is set for 1:05 p.m. ET. Let’s analyze BetMGM Sportsbook’s lines around the Red Sox vs. Orioles odds and make our expert MLB picks and predictions for the best bets.

Season series: Orioles lead 3-0

Boston came away with a 2-1 win Sunday as a -138 home favorite vs. the Milwaukee Brewers. LF Jarren Duran hit the go-ahead RBI single in the bottom of the 8th inning as the Red Sox salvaged a 3-game series after dropping the first 2 games.

Baltimore won 4-1 at the Chicago White Sox Sunday, covering as a -160 favorite. RHP Kyle Bradish tossed 7 innings of no-hit ball before the bullpen took over and yielded 1 run on 1 hit. Bradish finished with 11 K’s as the Orioles completed a 4-game sweep of the White Sox — a nice rebound after losing 3 straight at the St. Louis Cardinals midweek.

Red Sox at Orioles projected starters

RHP Cooper Criswell vs. LHP Cole Irvin

Criswell (2-1, 2.86 ERA) makes his 8th start. He has a 1.13 WHIP, 2.1 BB/9 and 8.8 K/9 through 34 2/3 innings.

  • Last start: No-decision, 5 1/3 IP, 2 ER, 6 H, 1 BB, 6 K in 5-2 win at Tampa Bay Rays Tuesday
  • First career start vs. Orioles

Irvin (4-2, 3.15 ERA) makes his 8th start and 10th appearance. He has a 1.09 WHIP, 1.6 BB/9 and 5.9 K/9 through 45 2/3 innings.

  • Last outing: Loss, 3 1/3 relief IP, 3 ER (5 R), 6 H, 0 BB, 2 K in 5-4 loss at Cardinals Wednesday
  • Last start: Win, 5 2/3 IP, 2 ER, 5 H, 1 BB, 6 K in 4-2 home victory vs. Arizona Diamondbacks May 10
  • Career vs. Red Sox: 0-1, 5.16 ERA (22 2/3 IP, 13 ER), 1.32 WHIP, 6.8 K/9 in 6 outings, including 3 starts
  • 2024 vs. Red Sox: 1 start, no-decision, 5 IP, 5 ER, 7 H, 3 BB, 4 K in 7-5 road win April 10

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Red Sox at Orioles odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Sunday at 9:55 p.m. ET.

  • Moneyline (ML): Red Sox +140 (bet $100 to win $140) | Orioles -165 (bet $165 to win $100)
  • Run line (RL)/Against the spread (ATS): Red Sox +1.5 (-150) | Orioles -1.5 (+125)
  • Over/Under (O/U): 9 (O: +100 | U: -120)

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Red Sox at Orioles picks and predictions

Prediction

Orioles 7, Red Sox 3

Moneyline

PASS.

The Orioles (-165) should win here, but the juice is not worth the risk of backing, especially with the Red Sox winning their last 4 games. Bet on the spread and/or total instead.

Run line/Against the spread

BET ORIOLES -1.5 (+125).

Baltimore is 7-3 in its last 10 matchups vs. Boston. In the 7 wins, the Orioles have won by at least 2 runs 6 times, including in each of their last 2 victories in Baltimore.

The Orioles are 28-23 ATS this season, while the Red Sox are only 23-30 ATS, according to Teamrankings.com.

Over/Under

LEAN OVER 9 (+100).

The Over has hit in 2 of Baltimore’s last 3 home games and is 6-2-2 in its last 10 overall. For Boston, the Over is 4-2 in its last 6 road games. The Over has also hit in each of the last 2 Boston-Baltimore matchups.

This is only a lean because the Over and Under have been very even in recent matchups between these squads at 5-4-1 O/U.

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