The New York Giants (1-4) will visit the Buffalo Bills (3-2) at Highmark Stadium in Orchard Park, New York on Sunday night.
Opening the week, the Giants were listed as 14.5-point road underdogs and that’s where the spread remains as of this writing after briefly dipping to +14.
Let’s take a look at who some of the experts and insiders around the league are taking in the Week 6 matchup:
| Expert | Pick | Score (if applicable) |
| Dan Graziano (ESPN) | Bills | N/A |
| Jeremy Fowler (ESPN) | Bills | N/A |
| Seth Wickersham (ESPN) | Bills | N/A |
| Pete Prisco (CBS) | Bills | 37-14 |
| John Breech (CBS) | Bills | 30-20 |
| Jordan Dajani (CBS) | Bills | 35-13 |
| Nate Davis (USA TODAY) | Bills | 30-13 |
| Lorenzo Reyes (USA TODAY) | Bills | 41-10 |
| Bill Bender (Sporting News) | Bills | 35-21 |
| Vinnie Iyer (Sporting News) | Bills | 42-17 |
For the second consecutive week, the entire panel above picks the Giants to lose and this time, expectations are that they’re completely blown out of the water. Even if they were fully healthy, that would still likely be the case.
But the lack of faith in the Giants does not begin or end here. According to NFL Pickwatch, 98 percent of all experts around the league are picking the Bills to win.
NFL fans share similar sentiments with 99 percent of all picks favoring Buffalo on Sunday night.
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