San Francisco Giants at New York Yankees odds, picks and predictions

Analyzing Thursday’s San Francisco Giants at New York Yankees odds and lines, with MLB expert picks, predictions and best bets.

The San Francisco Giants and New York Yankees swing into the 2023 season with a Thursday matinee at Yankee Stadium. First pitch is slated for 1:05 p.m. ET. Let’s analyze Tipico Sportsbook’s lines around the Giants vs. Yankees odds and make our expert MLB picks and predictions for the best bets.

Season series: First meeting since 2019 when the Yankees swept 3 games in San Francisco.

San Francisco went 81-81 and placed 3rd in the NL West last season. The Giants were 14-7 with a plus-40 in run differential in April, but struggled after that. The Giants were somewhat undone by a 22-27 record in 1-run games.

New York was a bit record-unlucky in 2022, only parlaying a plus-1.48 in average run differential into a 99-63 record. The Yankees logged a pedestrian 42-39 mark on the road, but they tied the Los Angeles Dodgers for the best home record in MLB at 57-24.

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Giants at Yankees projected starters

RHP Logan Webb vs. RHP Gerrit Cole

Webb went 15-9 with a 2.90 ERA a year ago. He clocked a 1.16 WHIP, 2.3 BB/9 and 7.6 K/9 in 192 1/3 IP.

  • Has allowed a .768 OPS in March/April games during his career (under .655 in each month May-August)
  • Owned wide platoon splits last season, holding right-handed bats to a .548 OPS while yielding a .730 mark against lefties

Cole logged a 13-8 mark while posting a 3.50 ERA in 2022. The veteran right-hander notched a 1.02 WHIP, 2.2 BB/9 and 11.5 K/9 in 200 2/3 IP.

  • Struggled in 1st 3 starts last season: 6.35 ERA, .852 OPS allowed
  • Registered a 3.20 ERA, 0.94 WHIP (with better BB/9 and K/9 numbers) at Yankee Stadium last year

Giants at Yankees odds

Provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Wednesday at 12:37 p.m. ET.

  • Moneyline: Giants +160 (bet $100 to win $160) | Yankees -190 (bet $190 to win $100)
  • Run line (RL)/Against the spread (ATS): Giants +1.5 (-140) | Yankees -1.5 (+120)
  • Over/Under (O/U): 7.5 (O: -102 | U: -125)

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Giants at Yankees picks and predictions

Prediction

Yankees 4, Giants 3

Moneyline

Webb logged a 1.61 WHIP while allowing 3 HR in spring training. Cole was much sharper, punching out 27 batters against 1 BB in 21 2/3 IP.

Spring training stats are misunderstood: They can be quite useful in early-season betting. And with New York holding better cards in the bullpen and lineup categories, there is some value edge in the YANKEES (-190).

Run line/Against the spread

With this top-shelf pitching matchup, temps in the low-40s and 2 fresh bullpens, expect a low scoring game. PASS on trying to get the Yankees by with a multi-run lean.

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Over/Under

Both clubs posted solid batting numbers in spring training, but the market is on to these starters. And the expected run-suppressant weather. AVOID.

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