The San Francisco 49ers (6-5) and Seattle Seahawks (3-8) hook up Sunday in Week 13 at Lumen Field. Kickoff is slated for a 4:25 p.m. ET. Below, we look at the 49ers vs. Seahawks odds and lines; check back for our NFL picks and predictions.
The 49ers beat the visiting Minnesota Vikings 34-26 in Week 12. It was the third consecutive win and cover for San Francisco, which was a 4-point favorite against the Vikes. The 49ers finished with 208 rushing yards, led by RB Elijah Mitchell (133 yards, 1 TD) and WR Deebo Samuel (66 yards, 2 TDs), who unfortunately, exited in third quarter with a groin injury and is expected to miss one or two games. QB Jimmy Garoppolo added 230 passing yards with a touchdown and an interception.
The Seahawks lost 17-15 as 1.5-point favorites at the Washington Football Team Monday night. QB Russell Wilson (247 passing yards, 2 TDs) made it interesting – on his 33rd birthday – when he found WR Freddie Swain for a 32-yard touchdown pass with 15 seconds to go, but Wilson was picked off on the 2-point conversion attempt. It’s the first time he has lost three in a row as Seattle’s starting QB. The Seahawks, who scored just 28 points in the three losses, have pretty much dropped out of playoff contention with a 1-6 SU showing over the last seven games.
Also see: All Week 13 odds and lines
49ers at Seahawks odds, spread and lines
Odds provided by Tipico Sportsbook; access USA TODAY Sports’ betting odds for a full list. Lines last updated Tuesday at 7:20 a.m. ET.
- Money line: 49ers -175 (bet $175 to win $100) | Seahawks +140 (bet $100 to win $140)
- Against the spread (ATS): 49ers -3.5, +100 (bet $100 to win $100) | Seahawks +3.5, -120 (bet $120 to win $100)
- Over/Under (O/U): 45.5, O: -110 (bet $110 to win $100) | U: -110 (bet $110 to win $100)
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2021 betting stats:
- ML: 49ers 6-5 | Seahawks 3-8
- ATS: 49ers 5-6 | Seahawks 5-6
- O/U: 49ers 6-5 | Seahawks 1-10
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49ers at Seahawks head-to-head
The Seahawks lead the all-time series 29-17, including 1-0 in the postseason – a 23-17 road win in the 2013 NFC Championship Game.
Seattle has won the last three meetings, including a 28-21 road victory as a 2.5-point underdog in Week 4. The last time they faced off in Seattle, the Seahawks claimed a 37-27 win as 1-point favorites in Week 8 of last season.
Including the 2013 NFC title game, the Seahawks are 14-2 in the last 16 vs. the 49ers.
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