Ole Miss at Alabama odds, picks and prediction

Analyzing Saturday’s Ole Miss at Alabama odds and lines, with college football expert picks, predictions and best bets.

The No. 12 Ole Miss Rebels (3-0, 0-0 SEC) and No. 1 Alabama Crimson Tide (4-0, 1-0) meet Saturday at Bryant-Denny Stadium in Tuscaloosa, Ala. Kickoff is scheduled for 3:30 p.m. ET. Below, we look at the Ole Miss vs. Alabama odds and lines, and make our expert college football picks, predictions and bets.

Ole Miss has been flexing that offensive muscle and getting better over time. The Rebels dropped 43 on Louisville in a neutral-site win in the opener, they posted 54 in a win over FCS Austin Peay and then 61 last week against a good Tulane side.

Alabama has registered 44 or more points in three games, including a dominant opening-game win over Miami at a neutral site. They also passed a stern test in Florida, winning 31-29. The Tide roll in with three consecutive Over results.

Rankings according to the AFCA Coaches Poll powered by USA TODAY Sports.

Ole Miss at Alabama odds, spread and lines

Odds provided by Tipico Sportsbook; access USA TODAY Sports’ betting odds for a full list. Lines last updated Thursday at 7:50 a.m. ET.

  • Money line: Ole Miss +380 (bet $100 to win $380) | Alabama -540 (bet $540 to win $100)
  • Against the spread (ATS): Ole Miss +14.5 (-108) | Alabama -14.5 (-112)
  • Over/Under (O/U): 80.5 (O: -110 | U: -110)

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Ole Miss at Alabama odds, lines, picks and predictions

Prediction

Alabama 45, Ole Miss 39

Money line

It’s the pupil, Lane Kiffin, leading his high-powered offense into Alabama to face the teacher, Nick Saban.

This game has all the potential to be a high-flying, entertaining affair with Alabama (-540) pulling it out at home. But you can’t risk seven times your potential return in what could be a close game.

AVOID, and look to the spread instead.

Against the spread

I think OLE MISS +14.5 (-108) is an absolute steal. QB Matt Corral and the Rebels offense is legit, and they should put some serious points on the board, even against the Tide.

Alabama -14.5 (-112) has the one thing Ole Miss hasn’t had yet, and that’s a test. They escaped at Florida, and know how to win a close game. That experience will help them pull another one out of the hat here, but the Rebels will keep it super close.

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Over/Under

Initially, playing the OVER 80.5 (-110) looks like a ridiculous play. But these are two extremely high-powered offenses capable of hitting the 50’s without breaking a sweat.

Corral will put up the points, and QB Bryce Young has proven he is the next great quarterback for Saban. Old school fans might not like the lack of defense, and video game appearance of this one, but I wouldn’t be surprised to see these teams flirt with 90.

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