WR Deebo Samuel
Samuel is the receiver who has benefited the most in Kittle’s absence and earned his role as the 49ers’ No. 2 receiver. The rookie has 16 receptions for 246 yards the last two games with Kittle out and Emmanuel Sanders playing just 36 percent of the snaps due to a rib injury. Sanders should be good to go Sunday, but the more viable options the better and Samuel has slowly become one in the offense.