TE George Kittle

With how much Kittle has practiced this week, albeit in a non-contact jersey, Sunday should be his first game since injuring his knee and ankle on Halloween. He’ll obviously be a boost for the offense, giving Garoppolo a consistent receiver he’s been lacking the past two weeks. However, if Kittle does miss Sunday night or is limited, the 49ers receivers will once again need to take an extra step up to replace his production. The run game is where San Francisco might see the biggest change with Kittle in the lineup. He’s a superb blocker whose productivity hasn’t been replicated by any of the other tight ends playing in his absence.