After last week’s embarrassing loss to the Miami Dolphins at home, the Indianapolis Colts desperately need a rebound on Sunday when the Jaguars visit Lucas Oil Stadium. This is the first time these two teams meet this season.

The Jaguars will be going through a quarterback change this week as Nick Foles will be making his first start since he broke his collarbone Week 1 against Kansas City. Gardner Minshew has held down the fort but has ultimately struggled in recent weeks.

The offense will look different with Foles under center no doubt, but the way this season has gone anything can happen. Outside of the quarterback position, there are plenty of talented players on Jacksonville’s roster.

Here are four Jaguars the Colts must game plan to win in Week 11:

RB Leonard Fournette

The Colts have been getting better in run defense, but Fournette may be one of the better backs the Colts get to face this season. Averaging 4.8 yards per carry, he is a tough, downhill runner who can not be brought down with arm tackles.

Fournette has 831 yards on the year but only has gotten in the end zone once. The Jaguars struggle in the red zone and rarely turn to their running back in key third-down situations. Regardless, the Colts front seven must be able to stop Fournette if they want to pick up a win. By stopping him, the rest of their offensive scheme will suffer.