The Penn State Nittany Lions are looking for a rebound season on the field this fall. After a disappointing 2020 season, Penn State is out for revenge against a number of opponents around the Big Ten this season. Penn State also faces one of its most challenging seasons in years with some of the toughest road trips in the Big Ten and a home game against a team from the SEC.
For the second year in a row, Penn State will open its football season on the road in Big Tern play. The Nittany Lions travel to Madison, Wisconsin to take on Big Ten West contender Wisconsin. Penn State also makes road trips to Iowa and Ohio State this fall. The home schedule is highlighted by a Week 3 matchup with Auburn and notable division games against Indiana and Michigan.
Below is the complete 2021 football schedule for Penn State. All times are eastern.
Penn State Football 2021 Schedule
| Week | Date | Opponent | Time |
| 1 | Sept. 4 | at Wisconsin | 12:00 p.m. |
| 2 | Sept. 11 | vs. Ball State | 3:30 p.m. |
| 3 | Sept. 18 | vs. Auburn | 7:30 p.m. |
| 4 | Sept. 25 | vs. Villanova | TBA |
| 5 | Oct. 2 | vs. Indiana | TBA |
| 6 | Oct. 9 | at Iowa | TBA |
| 7 | Oct. 16 | Open Week | |
| 8 | Oct. 23 | vs. Illinois | 12:00 p.m. |
| 9 | Oct. 30 | at Ohio State | TBA |
| 10 | Nov. 6 | at Maryland | TBA |
| 11 | Nov. 13 | vs. Michigan | TBA |
| 12 | Nov. 20 | vs. Rutgers | TBA |
| 13 | Nov. 27 | at Michigan State | TBA |