Week 1 first look: Louisiana Tech Bulldogs at Mississippi State Bulldogs odds and lines, MSU expected to cruise

Previewing the college football Week 1 matchup between the Louisiana Tech Bulldogs and Mississippi State Bulldogs, with odds, trends and head-to-head records.

The Louisiana Tech Bulldogs and Mississippi State Bulldogs open their 2021 regular season Saturday at Davis Wade Stadium. Kickoff is scheduled for 4 p.m. ET. Below, we look at the Louisiana Tech vs. Mississippi State odds and lines; check back for our college football picks and predictions.

Last year ended on a sour note for Louisiana Tech as it was thumped 38-3 by Georgia Southern in the New Orleans Bowl, but it was still a successful season. The Bulldogs were 0-3 SU/ATS against non-Conference USA FBS teams in 2020.

Mississippi State won just four games, but it capped off its seasons with a win in the Armed Forces Bowl over Tulsa. The “Air Raid” offense of head coach Mike Leach is still a work in progress as he gets more people in place to fit his offensive scheme.

Louisiana Tech at Mississippi State odds, spread and lines

Odds provided by Tipico Sportsbook; access USA TODAY Sports’ betting odds for a full list. Lines last updated Monday at 6:53 p.m. ET.

  • Money line: Louisiana Tech +850 (bet $100 to win $850) | Mississippi State -1800 (bet $1,800 to win $100)
  • Against the spread/ATS: Louisiana Tech +22.5 (-108) | Mississippi State -22.5 (-112)
  • Total (Over/Under): 52.5, O: -110 (bet $110 to win $100) | U: -110 (bet $110 to win $100)

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2020 betting stats:

  • ML: Louisiana Tech 5-5 | Mississippi State 4-7
  • ATS: Louisiana Tech 4-6 | Mississippi State 5-6
  • O/U: Louisiana Tech 6-4 | Mississippi State 4-7

Louisiana Tech at Mississippi State head-to-head

These two schools have met on the gridiron 14 times, most recently Nov. 3, 2018. Mississippi State won 45-3 in Starkville, Miss., in that one, and has won four straight in the series dating back to Aug. 30, 2008.

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