Safety (4)
| SAF1 | SAF2 | SAF3 | SAF4 |
| Malik Hooker | Khari Willis | Julian Blackmon | George Odum |
Analysis: This might not be the Week 1 depth chart due to injuries, but this is what it will look like for the most part. There is plenty of curiosity regarding Hooker and his fifth-year option. The Colts have yet to exercise it and have until the end of May to do so. Willis had a strong rookie campaign and will return as a versatile piece in the defensive backfield. The third-round pick in Blackmon is the injury case. He tore his ACL in December and likely won’t be ready to go by the time the season rolls around. He’s rangy and athletic but raw in terms of the nuances of the safety position. He’s intriguing but he won’t make an impact early on. Odum will continue his ways providing excellent depth and special teams work.
Notable cuts: Rolan Milligan (once Blackmon returns)