Virginia at Clemson odds, picks and predictions

Analyzing Saturday’s Virginia at Clemson odds and lines, with college football expert picks, predictions and best bets.

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The Virginia Cavaliers (4-2, 2-1 ACC) visit the Clemson Tigers (5-1, 4-0) Saturday. Kickoff from Memorial Stadium is scheduled for noon ET (ACC Network). Let’s analyze BetMGM Sportsbook’s college football odds around the Virginia vs. Clemson odds, and make our expert college football picks and predictions.

Virginia snapped a 2-game winning streak with a 24-20 loss against Louisville Saturday, covering as a 7-point home underdog. QB Anthony Colandrea went 26 of 45 for 279 yards with a TD while WR Malachi Fields hauled in 9 receptions for 129 yards.

Clemson has won 5 games in a row after taking down Wake Forest 49-14 Saturday and covering as a 21-point road favorite. QB Cade Klubnik went 31 of 41 for 309 yards with 3 TDs while RB Phil Mafah carried the ball 19 times for 108 yards and 2 TDs.

Clemson is No. 9 in the US LBM Coaches Poll.

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Virginia at Clemson odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list of college football odds. Lines last updated Friday at 11:37 p.m. ET.

  • Moneyline (ML): Virginia +900 (bet $100 to win $900) | Clemson -1600 (bet $1600 to win $100)
  • Against the spread (ATS): Virginia +21 (-110) | Clemson -21 (-110)
  • Over/Under (O/U): 57.5 (O: -110 | U: -110)

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Virginia at Clemson picks and predictions

Prediction

Clemson 41, Virginia 17

Moneyline

PASS.

There is no value on Clemson (-1600) to win Saturday.

Against the spread

BET CLEMSON -21 (-110).

Clemson has covered 4 straight games as a favorite of 17 or more points, including each of its last 3 at home. It has scored 40 or more points in 4 of its last 5 games and held opponents to 14 or fewer in each of its last 3. Virginia is a capable team, but it will not be able to compete on the road.

Over/Under

LEAN OVER 57.5 (-110).

Virginia has scored 20 or more points in 5 of its 6 games this season while allowing 24 or more in 4 of its last 5. Clemson has scored 29 or more points in each of its last 5 games, including 40 or more in 4 of its last 5.

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