UFC 264 predictions: Who’s picking Conor McGregor to take trilogy from Dustin Poirier?

Check out our staff members’ picks for the UFC 264 main card with a trilogy rubber match between Dustin Poirier and Conor McGregor.

Poirier
vs.
McGregor
Burns
vs.
Thompson
Hardy
vs.
Tuivasa
Aldana
vs.
Kunitskaya
Moutinho
vs.
O’Malley
MMA Junkie readers’
consensus picks
2021: 86-57
poirier2021
Poirier
(58%)
thompson2021
Thompson
(73%)
tuivasa2021
Tuivasa
(67%)
kunitskaya2021
Kunitskaya
(58%)
omalley2021
O’Malley
(88%)
Ken Hathaway
@kenshathaway
2021: 97-60
trophy copy 2018 Champion
poirier2021
Poirier
burns2021
Burns
hardy2021
Hardy
aldana2021
Aldana
omalley2021
O’Malley
John Morgan
@MMAjunkieJohn
2021: 94-63
poirier2021
Poirier
burns2021
Burns
hardy2021
Hardy
aldana2021
Aldana
omalley2021
O’Malley
Simon Samano
@SJSamano
2021: 94-63
poirier2021
Poirier
burns2021
Burns
tuivasa2021
Tuivasa
aldana2021
Aldana
omalley2021
O’Malley
Mike Bohn
@MikeBohnMMA
2021: 93-64
trophy copy 2014 Champion
poirier2021
Poirier
thompson2021
Thompson
tuivasa2021
Tuivasa
kunitskaya2021
Kunitskaya
omalley2021
O’Malley
Dan Tom
@DanTomMMA
2021: 92-65
trophy copy 2020 Champion
poirier2021
Poirier
thompson2021
Thompson
tuivasa2021
Tuivasa
aldana2021
Aldana
omalley2021
O’Malley
Nolan King
@mma_kings
2021: 92-65
mcgregor2021
McGregor
thompson2021
Thompson
tuivasa2021
Tuivasa
aldana2021
Aldana
omalley2021
O’Malley
Farah Hannoun
@Farah_Hannoun
2021: 91-66
poirier2021
Poirier
thompson2021
Thompson
tuivasa2021
Tuivasa
aldana2021
Aldana
omalley2021
O’Malley
Danny Segura
@dannyseguratv
2021: 91-66
poirier2021
Poirier
thompson2021
Thompson
tuivasa2021
Tuivasa
aldana2021
Aldana
omalley2021
O’Malley
Brian Garcia
@thegoze
2021: 91-66
trophy copy 2017 Champion
mcgregor2021
McGregor
burns2021
Burns
tuivasa2021
Tuivasa
aldana2021
Aldana
omalley2021
O’Malley
George Garcia
@MMAjunkieGeorge
2021: 91-66
mcgregor2021
McGregor
burns2021
Burns
tuivasa2021
Tuivasa
aldana2021
Aldana
omalley2021
O’Malley
Matt Erickson
@MMAjunkieMatt
2021: 90-67
mcgregor2021
McGregor
thompson2021
Thompson
tuivasa2021
Tuivasa
aldana2021
Aldana
omalley2021
O’Malley
Abbey Subhan
@kammakaze
2021: 88-69
mcgregor2021
McGregor
thompson2021
Thompson
tuivasa2021
Tuivasa
aldana2021
Aldana
omalley2021
O’Malley
Matthew Wells
@MrMWells
2021: 22-19
poirier2021
Poirier
burns2021
Burns
tuivasa2021
Tuivasa
kunitskaya2021
Kunitskaya
omalley2021
O’Malley
BetMGM
Betting Favorites
poirier2021
Poirier -125
thompson2021
Thompson -160
tuivasa2021
Tuivasa -145
aldana2021
Aldana -120
omalley2021
O’Malley -900

The UFC is back after a week off with a blockbuster trilogy rubber match in front of fans in Las Vegas.

UFC 264 takes place Saturday at T-Mobile Arena in Las Vegas. The main card airs on pay-per-view following prelims on ESPN and ESPN+.

(Click here to open a PDF of the staff picks grid in a separate window.)

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In the lightweight main event, [autotag]Dustin Poirier[/autotag] (27-6 MMA, 19-5 UFC) takes on former lightweight and featherweight champion [autotag]Conor McGregor[/autotag] (22-5 MMA, 10-3 UFC) in a trilogy rubber match. Each fighter has a win over the other by knockout. Poirier is a slight -125 betting favorite at BetMGM, and he’s got the lead in the picks from our 13 editors, writers, radio hosts and videographers at 8-5.

In the co-feature, [autotag]Gilbert Burns[/autotag] (19-4 MMA, 12-4 UFC) meets [autotag]Stephen Thompson[/autotag] (16-4-1 MMA, 11-4-1 UFC) at welterweight. Thompson is a -160 favorite, but he has just the smallest possible edge in the picks at 7-6.

Also on the main card, [autotag]Greg Hardy[/autotag] (7-3 MMA, 4-3 UFC) takes on [autotag]Tai Tuivasa[/autotag] (12-3 MMA, 5-3 UFC) in a heavyweight bout. Tuivasa is a -145 favorite and has a whopping 11-2 lead in the picks from our staff members.

[autotag]Irene Aldana[/autotag] (12-6 MMA, 5-4 UFC) meets [autotag]Yana Kunitskaya[/autotag] (14-5 MMA, 4-2 UFC) in a women’s bantamweight bout. Aldana has a slim -120 edge at the betting window, but she’s got a hefty 11-2 lead in the picks. Oddly enough, our readers are siding with Kunitskaya at a 58 percent clip.

And to open the main card, [autotag]Sean O’Malley[/autotag] (13-1 MMA, 5-1 UFC) is our only unanimous pick in his bantamweight bout against short-notice replacement opponent [autotag]Kris Moutinho[/autotag] (9-4 MMA, 0-0 UFC), who is making his UFC debut. O’Malley is the biggest favorite on the entire card at 9-1 and has a 13-0 shutout in the picks from our staff members.

In the MMA Junkie reader consensus picks, Poirier (58 percent), Thompson (73 percent), Tuivasa (67 percent), Kunitskaya (58 percent) and O’Malley (88 percent) are the choices.

Check out all the picks above.

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