Tennessee Titans at New Orleans Saints odds, picks and predictions

Analyzing Sunday’s Tennessee Titans at New Orleans Saints Week 1 odds and lines, with expert NFL picks and predictions.

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The Tennessee Titans and the New Orleans Saints open their 2023 NFL regular seasons at the Caesars Superdome in New Orleans on Sunday. Kickoff is scheduled for 1 p.m. ET (CBS). Below, we analyze BetMGM Sportsbook’s lines around the Titans vs. Saints odds, and make our expert NFL picks and predictions.

The Titans head to the Gulf Coast looking to get off to a hot start. QB Ryan Tannehill hung onto his starting job in training camp and the preseason, holding off a pair of drafted QBs in the past 2 years, Will Levis and Malik Willis.

The Saints look to get off to a grand style in the QB Derek Carr era. RB Jamaal Williams is likely to be leaned up heavily in Week 1, especially with RB Alvin Kamara suspended for 3 games by the NFL.

These teams last met on Nov. 14, 2021, with the Titans coming away with a 23-21 win as the Saints covered the 3-point line.

This is the first meeting in New Orleans since Nov. 8, 2015, when the Titans won 34-28 in overtime as 7-point underdogs. The Titans have won 4 straight visits to New Orleans dating back to the organization’s time as the Houston Oilers. The last time the Saints won a home game against the Oilers/Titans franchise was Sept. 5, 1993.

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Titans at Saints odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Saturday at 9:25 a.m. ET.

  • Moneyline (ML): Titans +130 (bet $100 to win $130) | Saints -155 (bet $155 to win $100)
  • Against the spread (ATS): Titans +3 (-120) | Saints -3 (+100)
  • Over/Under (O/U): 41.5 (O: -110 | U: -110)

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Titans at Saints key injuries

Titans

  • CB Tre Avery (hamstring) out
  • LB Harold Landry (abdomen) questionable
  • OL Dillon Radunz (knee) questionable

Saints

  • S J.T. Gray (knee) out
  • RB Kendre Miller (hamstring) questionable
  • WR Tre’Quan Smith (groin) out

Titans at Saints picks and predictions

Prediction

Titans 23, Saints 21

Moneyline

The TITANS (+130) are worth a look as road ‘dogs.

Some streaks cannot be explained, and the Titans just seem to show out whenever they visit New Orleans. Much of the personnel has changed since the most recent visit to the Big Easy in 2015. However, I believe in strange streaks like this. The Titans have kept the fire of the Oilers alive, looking to be the kings of the Gulf Coast.

If you’re not into circumstantial streaks, the Titans have a healthy RB Derrick Henry, and he will be facing a Saints rush defense that allowed 4.5 yards per carry last season, ranking 24th in the NFL. The Titans, on the flip side, were No. 1 against the run, which bodes well for a team without Kamara. Don’t forget newly-acquired WR DeAndre Hopkins if the Titans want to go vertical.

Against the spread

The TITANS +3 (-120) are an OK play with the points if you can’t bring yourself to take them straight up.

Tennessee was just 2-3 straight up (SU) and 2-2-1 against the spread (ATS) against the NFC last season, so there is some risk. However, I like the rush D against the Saints, and I like Henry and the Titans’ run game to roll up big numbers.

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Over/Under

OVER 41.5 (-110) is the lean, but play a half-unit play at most.

This game figures to see a decent amount of rushing on the part of the Titans, but look for the Saints to air it out frequently with their “new Carr” under center. We aren’t going to have a defensive slog, but we won’t have a shootout under the dome, either. With the controlled conditions and decent passing on each side, the total should inch just across the finish line.

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