Tampa Bay Buccaneers at Dallas Cowboys odds, picks and predictions

Analyzing Sunday’s Tampa Bay Buccaneers at Dallas Cowboys Week 1 odds and lines, with expert NFL picks, predictions and best bets.

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QB Tom Brady and the Tampa Bay Buccaneers open the 2022 season on the road in a Sunday night game against the Dallas Cowboys. Kickoff is at 8:20 p.m. ET (NBC) at AT&T Stadium. Below, we analyze Tipico Sportsbook‘s lines around the Buccaneers vs. Cowboys odds, and make our expert NFL picks and predictions.

Following a playoff loss in the divisional round, the Bucs had an interesting offseason. It began with the retirement of Brady, only for him to change his mind 40 days later and return for another season. Bruce Arians retired as  coach, moving into the front office, and Todd Bowles replaced him.

The Cowboys won the NFC East last season and seek to defend that title. They traded WR Amari Cooper and brought back WR Michael Gallup – though he’s out with a knee injury – while bolstering their pass rush with the addition of DE Dante Fowler.

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Buccaneers at Cowboys odds

Provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 4:45 a.m. ET.

  • Money line (ML): Buccaneers -135 (bet $135 to win $100) | Cowboys +115 (bet $100 to win $115)
  • Against the spread (ATS): Buccaneers -2.5 (-115) | Cowboys +2.5 (-105)
  • Over/Under (O/U): 50.5 (O: -105 | U: -115)

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Buccaneers at Cowboys key injuries

Buccaneers

  • WR Russell Gage (hamstring) questionable
  • WR Chris Godwin (knee) questionable

Cowboys

  • WR Michael Gallup (knee) out
  • S Jayron Kearse (neck) questionable

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Buccaneers at Cowboys picks and predictions

Prediction

Buccaneers 24, Cowboys 17

Money line

Brady has never lost to the Cowboys in 6 career matchups.

The Cowboys were not dominant at home in 2021, going 5-3 in the regular season. The Bucs were 6-3 on the road.

Tampa has questions on the offensive line, but Brady is still playing at a high level and Tampa’s defense is still the same unit that ranked 5th in points allowed last season.

It is a strong enough unit to limit the passing attack.

Take the BUCCANEERS (-135).

Against the spread

Last season, the Cowboys were the league’s best team against the spread, going 13-5 ATS overall. They were 3-1 ATS as underdogs.

The Buccaneers only won 2 games by fewer than 3 points, so if you like the Bucs to win, there is a good chance they will cover the spread.

The Cowboys lost by fewer than 3 points only once last season.

If you like the Cowboys to win, the money line is the better bet for you. If you like the Bucs to win outright as I do, take the BUCCANEERS -2.5 (-115) for the slightly better value over the money line.

Over/Under

Tampa was 10-9 O/U last season and Dallas was 8-10 O/U.

The Bucs held their opponents to under 20 points 8 times last season.

Last season in Week 1 when both teams played, they combined for 60 total points.

With both teams dealing with injured receivers they are counting on, there won’t be as many long, fast drives. Ball control will matter.

Take UNDER 50.5 (-115).

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