Chicago White Sox at San Francisco Giants odds, picks and predictions

Analyzing Sunday’s Chicago White Sox at San Francisco Giants odds and lines, with MLB expert picks and predictions.

The Chicago White Sox (37-39) and San Francisco Giants (40-36) cap off a 3-game interleague series Sunday afternoon at Oracle Park. First pitch is slated for 4:05 p.m. ET. Let’s analyze Tipico Sportsbook‘s lines around the White Sox vs. Giants odds with MLB picks and predictions.

Season series: Chicago leads 2-0.

The White Sox have taken the first 2 games of this series and are an impressive 9-4 in their last 13 road games. Over that stretch, Chicago has logged a .790 OPS while averaging 5.42 runs per game.

The Giants have struggled offensively at home lately and are just 3-9 in their last 12 games.

White Sox at Giants projected starters

RHP Lucas Gioloto vs. RHP John Brebbia

Giolito (4-4, 5.19 ERA) has made 13 starts this season. He has a 1.53 WHIP, 3.5 BB/9 and 10.6 K/9 in 69 1/3 IP.

  • Was solid in his last start (2 R in 6 IP at the Los Angeles Angels Monday), but his 5.19 ERA comes on the heels of logging a 3.47 ERA the last 3 years (2019-21).
  • Has coughed up multiple home runs in 6 of his last 11 starts. Being barreled up on 11.4% of balls in play (up from 6.7% last season).

Brebbia (3-1, 2.70 ERA) gets start in what figures as a bullpen game for the Giants. The righty reliever has made 1 start in 36 appearances this season. He’s has a 1.20 WHIP, 2.7 BB/9 and 8.9 K/9 in 33 1/3 IP.

  • Owns a 3.30 ERA over 215 career games.
  • Last started a game June 3. Went 1 inning versus Miami.

White Sox at Giants odds and lines

Odds provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated 8:36 a.m. ET.

  • Money line: White Sox -105 (bet $100 to win $105) | Giants -115 (bet $115 to win $100)
  • Run line (RL): White Sox -1.5 (+155) | Giants +1.5 (-190)
  • Over/Under (O/U): 8.5 (O: -105 | U: -120)

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White Sox at Giants picks and predictions

Prediction

White Sox 4, Giants 3

Money line

Chicago’s record is a tad suspect because of a 13-8 mark in 1-run games. But the Pale Hose have been better in the bullpen of late.

Giolito has pitched through a very tough schedule. With his solid effort last time out, peg the White Sox as being worthy of a level wager here. BACK CHICAGO (-105).

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Run line/Against the spread

PASS: Avoid the added juice.

Over/Under

Both clubs have underlying analytics that indicate a bit of bad luck in the run-prevention department. Giolito has been hammered by fly balls leaving  on an 18.5% clip and by a batting average on all balls in play of .360.

Despite the forecast for a double-digit breeze aiding the batters, there is some leverage on the UNDER 8.5 (-120).

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