Washington Nationals at St. Louis Cardinals odds, picks and predictions

Analyzing Friday’s Washington Nationals at St. Louis Cardinals odds and lines, with MLB expert picks, predictions and best bets.

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The Washington Nationals (47-56) take on the St. Louis Cardinals (53-49) Friday in the opener of a 3-game set at Busch Stadium at 8:15 p.m. ET. Let’s analyze BetMGM Sportsbook’s lines around the Nationals vs. Cardinals odds and make our expert MLB picks and predictions for the best bets.

Season series: Cardinals lead 3-1

The Nats were swept by the San Diego Padres in a 3-game series that ended with RHP Dylan Cease no-hitting them in a 3-0 setback Thursday. This is on the heels of the Nats sweeping a 3-game series over the Cincinnati Reds. The one to watch is OF Jesse Winker. He is hitting .352 with 11 homers and 34 RBIs in 241 career at-bats against the Cardinals. That improves to .379-7-17 in 95 ABs at Busch.

The Cardinals followed up a dramatic 2-1 win over stud RHP Paul Skenes with a half-hearted 5-0 loss Wednesday. They outhit the Pittsburgh Pirates, drew 9 walks and could not score a run, which is hard to fathom. The Cards are dreadful against lefties at .223/.288/.335 BA/OBP/SLG.

Nationals at Cardinals projected starters

LHP MacKenzie Gore vs. RHP Sonny Gray

Gore (6-8, 4.20 ERA) makes his 21st start. He has a 1.46 WHIP, 3.7 BB/9 and 10.5 K/9 through 100 2/3 innings.

  • Last start: No-decision, 2 IP, 3 ER, 2 H, 4 BB, 2 K in 5-4 home win Saturday against Cincinnati Reds
  • 2 career starts vs. Cardinals: 0-1, 9.64 ERA, 2.36 WHIP, 7 BB, 13 K in 9 1/3 IP
  • July 6 vs. St. Louis: No-decision, 3 1/3 IP, 5 ER, 6 H, 5 BB, 5 K in 14-6 home win

Gray (10-6, 3.54 ERA) makes his 19th start. He has a 1.06 WHIP, 2.0 BB/9 and 11.1 K/9 through 106 2/3 innings.

  • Last start: Win, 7 IP, 5 ER, 8 H, 0 BB, 10 K in 9-5 victory Saturday at Atlanta Braves
  • Last start vs. Nationals: No-decision, 5 IP, 5 ER, 8 H, 1 BB, 6 K in 7-6 road win in 11 innings July 5
  • Last 5 starts vs. Nats: 2-1, 4.68 ERA, 1.36 WHIP, 25 K in 25 IP

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Nationals at Cardinals odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 1:01 p.m. ET.

  • Moneyline (ML): Nationals +145 (bet $100 to win $145) | Cardinals -175 (bet $175 to win $100)
  • Run line (RL)/Against the spread (ATS): Nationals +1.5 (-140) | Cardinals -1.5 (+115)
  • Over/Under (O/U): 7.5 (O: -115 | U: -105)

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Nationals at Cardinals picks and predictions

Prediction

Cardinals 5, Nationals 3

Moneyline

The Cards are bad against lefties, but they have seen Gore well. They had an off-day Thursday to recharge, and there’s no reason they should drop this game. They also dropped out of the 3rd Wild Card spot, and things have become urgent.

That said, -175 is too expensive for how inconsistent they are. Instead, SGP CARDINALS ML AND SONNY GRAY OVER 5.5 K’S (+145). Gray fanned 6 Nats July 5 and has 6+ K’s in 6 of 7 GS.

Run line/Against the spread

The Cardinals play entirely too many 1-run games to trust them on the RL. They are 19-14 in 1-run affairs. PASS, and devote your attention elsewhere.

Remember that dominance Winker has displayed against St. Louis? Take JESSE WINKER OVER 1.5 H+R+RBI (+125). He’s 3-for-6 lifetime against Gray.

Over/Under

It’s slated to be a humid, 82-degree evening with a light breeze blowing left-to-right. The Nats are 5-5 O/U, and the Cards are 4-6 O/U in their last 10. The Over is 8-2 in the last 10 meetings, though.

Gore has pitched against St. Louis twice and gave up 5 ER in each start. I look for the OVER 7.5 (-115) to cash.

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Washington Nationals at St. Louis Cardinals odds, picks and predictions

Analyzing Thursday’s Washington Nationals at St. Louis Cardinals odds and lines, with MLB expert picks and predictions.

The Washington Nationals (48-89) and St. Louis Cardinals (81-56) wrap up a 4-game set Thursday at Busch Stadium. First pitch is scheduled for 1:15 p.m. ET. Let’s analyze Tipico Sportsbook‘s lines around the Nationals vs. Cardinals odds with MLB picks and predictions.

Season series: Cardinals lead 4-2

The Nationals lost 6-5 Wednesday for their second consecutive loss. Washington had a 92.4% win probability after Nationals 1B Luke Voit hit a 2-run HR in the 8th inning, but St. Louis responded with a 5-run 9th inning to complete the comeback.

Cardinals SS Tommy Edman hit a walk-off 2-run double to secure St. Louis’ 6th win in its last 7 games. Edman’s second walk-off hit of the season helped St. Louis improve to 20-3 in its last 23 home games.

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Nationals at Cardinals projected starters

RHP Josiah Gray vs. RHP Adam Wainwright

Gray (7-9, 4.91 ERA) makes his 25th start. He has a 1.34 WHIP, 4.0 BB/9 and 10.0 K/9 through 128 1/3 IP.

  • Last start: Allowed 6 ER on 6 H and 4 BB with 2 K over 5 IP in a loss at the New York Mets Friday
  • Is 4-2 in day games with a 2.66 ERA (50 2/3 IP, 15 ER) while holding opponents to a .173 batting average over 9 starts

Wainwright (10-9, 3.21 ERA) makes his 28th start. He has a 1.20 WHIP, 2.4 BB/9 and 7.1 K/9 through 168 IP.

  • Last start: Allowed 4 ER on 9 H and 2 BB with 2 K over 5 IP in a win vs. the Chicago Cubs Saturday
  • Has won 4 of his last 5 decisions
  • First time facing Washington this season
  • Is 3-3 in day games with a 3.69 ERA (46 1/3 IP, 19 ER) with an opponent batting average of .258 over 8 starts

Nationals at Cardinals odds

Provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 6:30 a.m. ET.

  • Money line (ML): Nationals +230 (bet $100 to win $230) | Cardinals -300 (bet $300 to win $100)
  • Run line (RL)/Against the spread (ATS): Nationals +1.5 (+105) | Cardinals -1.5 (-130)
  • Over/Under (O/U): 7.5 (O: -115 | U: -107)

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Nationals at Cardinals picks and predictions

Prediction

Cardinals 3, Nationals 2

Money line

PASS.

St. Louis (-300) money line will most likely hit, but the price is too steep. The Cardinals could also be due for a let-down game after erasing a 4-run deficit in the 9th inning and walking off the Nationals Wednesday.

Run line/Against the spread

Gray is not a pitcher I would usually back, but he performs better in day games. While St. Louis has the better offense, they might underperform after such an emotional win. If Gray can continue to pitch well during the day, the Nationals should keep it close enough to cover the RL.

BET NATIONALS +1.5 (+105).

Over/Under

After an 11-run offensive showcase Wednesday, both offenses should regress toward the mean. St. Louis is coming off of an emotional and improbable comeback win. Don’t expect the same fireworks Thursday.

BET UNDER 7.5 (-107).

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Washington Nationals at St. Louis Cardinals odds, picks and predictions

Analyzing Wednesday’s Washington Nationals at St. Louis Cardinals odds and lines, with MLB expert picks and predictions.

The Washington Nationals (48-88) take on the St. Louis Cardinals (80-56) Wednesday in the 3rd game of a 4-game set at Busch Stadium. First pitch is set for 7:45 p.m. ET. Let’s analyze Tipico Sportsbook‘s lines around the Nationals vs. Cardinals odds with MLB picks and predictions.

Season series: Cardinals lead 3-2

The Nats were held in check Tuesday night, falling 4-1. They took the series opener by a 5-0 score Monday. Washington is 6-4 over its last 10 games and is a better road team this year at 26-41. The Nats are just 14-35 against left-handed starters, which they’ll encounter Wednesday.

The Cards strung together hits when they needed them and got 4 scoreless IP from their bullpen Tuesday. They’re 8-2, 15-5 and 22-8 over the last 10, 20 and 30 games, respectively, as they continue to roll. The Cards are one of the best home teams in baseball at 46-23.

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Nationals at Cardinals projected starters

RHP Cory Abbott vs. LHP Jordan Montgomery

Abbott (0-2, 4.39 ERA) makes his 5th start and 11th appearance. He has a 1.20 WHIP, 4.4 BB/9 and 8.1 K/9 in 26 2/3 IP.

  • Has thrown 21 pitches over 2 relief outings in September and might be limited to 40-50 pitches
  • Allowed 2 ER on 3 H and 1 BB with 5 K in 6 IP in last start Aug. 17 against the Chicago Cubs

Montgomery (8-3, 3.15 ERA) makes his 28th start. He has a 1.06 WHIP, 1.7 BB/9 and 7.7 K/9 in 151 1/3 IP.

  • Allowed 7 H and 2 BB over 6 scoreless IP with 4 K Friday against Cubs last time out
  • 5-0, 1.47 ERA, 0.93 WHIP and 7.9 K/9 in 6 GS with St. Louis

Nationals at Cardinals odds and lines

Odds provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 8:16 a.m. ET.

  • Money line (ML): Nationals +250 (bet $100 to win $250) | Cardinals -320 (bet $320 to win $100)
  • Run line (RL)/Against the spread (ATS): Nationals +1.5 (+110) | Cardinals -1.5 (-135)
  • Over/Under (O/U): 7.5 (O: -122 | U: -102)

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Nationals at Cardinals picks and predictions

Prediction

Cardinals 6, Nationals 3

Money line

The Nats could wind up with a bullpen game since Abbott isn’t exactly stretched out. That bodes well for the heavily favored Cards. The ML is way too expensive, but the price is right for the Cards to score 5. Take CARDINALS OVER 4.5 TOTAL RUNS (-130).

Look out for 2B/SS Tommy Edman, who is 10-for-23 (.435) with 3 doubles and 2 homers in the last 7 days. When prop bets are released closer to game time, he’s worth consideration.

Run line/Against the spread

St. Louis’ last 7 wins have been by more than a run. They’re solid with a 41-28 record on the RL at home. The price is at the edge of my limits for a RL wager so take the CARDINALS -1.5 (-135) for a HALF-UNIT.

Over/Under

Both games have gone Under thus far, and there’s a 5-mph gust coming in from left-center field. I don’t think it’ll matter when the Nats empty their ‘pen. St. Louis also used its top-3 relievers to get 4 innings Tuesday.

Take the OVER 7.5 (-122).

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Washington Nationals at St. Louis Cardinals odds, picks, and predictions

Analyzing Tuesday’s Washington Nationals at St. Louis Cardinals odds and lines, with MLB expert picks and predictions.

The Washington Nationals (48-87) take on the St. Louis Cardinals (79-56) in the 2nd game of a 4-game series Tuesday. First pitch at Busch Stadium is at 7:45 p.m. ET. Let’s analyze Tipico Sportsbook‘s lines around the Nationals vs. Cardinals odds with MLB picks and predictions.

Season series: Tied 2-2

The Nationals won Monday’s opener 6-0. Although the season is lost for Washington, it is 6-4 in its last 10 games and are looking to play spoiler heading down the stretch.

The Cardinals lead the NL Central by 7½ games over the Milwaukee Brewers. With 27 games to play, the Cards are looking to remain strong heading into the playoffs. With a 7-3 record over their last 10 games, they’re doing just that.

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Nationals at Cardinals projected starters

RHP Paolo Espino vs. LHP Jose Quintana

Espino (0-6, 4.22 ERA) makes his 16th start and 36th appearance. He has a 1.29 WHIP, 1.8 BB/9 and 7.0 K/9 through 96 IP.

  • Started 15 straight games after appearing out of the bullpen 20 times to start the season
  • Threw 5 innings with 1 ER, 5 H, 0 BB, 6 K in a no-decision at home against Oakland Athletics Thursday

Quintana (4-6, 3.47 ERA) makes his 27th start. He has a 1.33 WHIP, 2.9 BB/9 and 7.4 K/9 through 132 1/3 IP.

  • Coming off a rough start in his last outing where he managed only 4 2/3 IP, while giving up 2 ER on 7 H and 1 BB with 1 K in no-decision at Cincinnati Reds Wednesday
  • Since Aug. 2 trade from Pirates to Cardinals: 1-1, 3.38 ERA (29 1/3 IP, 11 ER), 1.53 WHIP, 3.7 BB/9, 6.1 K/9 in 6 starts
  • St. Louis is 5-1 in his 6 starts since trade

Nationals at Cardinals odds and lines

Odds provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 2:20 p.m. ET.

  • Money line (ML): Nationals +200 (bet $100 to win $200) | Cardinals -250 (bet $250 to win $100)
  • Run line (RL)/Against the spread (ATS): Nationals +1.5 (-108) | Cardinals -1.5 (-112)
  • Over/Under (O/U): 7.5 (O: -115 | U: -107)

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Nationals at Cardinals picks and predictions

Prediction

St. Louis 5 Washington 3

Money line

ST. LOUIS (-250) is the play.

The Cardinals are the better team in this game. Despite their shutout loss Monday, they have still outscored the Nationals this season 17-15. They should outscore them again here.

Run line/Against the spread

STAY AWAY.

Neither of these pitchers has performed well in recent outings. Quintana was pulled in the 5th inning in his most recent turn for the Cardinals, and Espino barely made it through the 5th last time out for the Nats.

Over/Under

OVER 7.5 (-115) is my FAVORITE PLAY for this game.

These pitchers are a combined 4-12 on the season in 41 combined starts. Both are also coming off a series of rocky outings. There should be some runs scored in this one after the Under hit Monday.

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Washington Nationals at St. Louis Cardinals odds, picks and predictions

Analyzing Monday’s Washington Nationals at St. Louis Cardinals odds and lines, with MLB expert picks and predictions.

The Washington Nationals (47-87) travel to the Gateway City to face the St. Louis Cardinals (79-55) Monday in the opener of a 4-game set at Busch Stadium. First pitch is set for 4:15 p.m. ET. Let’s analyze Tipico Sportsbook‘s lines around the Nationals vs. Cardinals odds with MLB picks and predictions.

Season series: Cardinals lead 2-1

Washington stunned the New York Mets by identical 7-1 scores Saturday and Sunday. Don’t look now, but the Nats have won 4 of 5 games as they attempt to slow down the surging Cards. The Nationals have had solid starting pitching and 5 scoreless IP from their bullpen across their last 2 games.

St. Louis is coming off a magical 3-game sweep of the Chicago Cubs. Tied 0-0 in the 8th inning Sunday, DH Albert Pujols stepped up to the plate with 1st base open. The Cubs elected to pitch to him, and he hit a monstrous 2-run homer over the bullpen in left field for career No. 695.

The Cardinals have won 4 games in a row, 7 of 8 and 23 of 30. They receive another boost as injured RHP Jack Flaherty returns from the IL Monday.

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Nationals at Cardinals projected starters

RHP Anibal Sanchez vs. RHP Jack Flaherty

Sanchez (1-5, 5.05 ERA) makes his 10th start. He has a 1.32 WHIP, 4.1 BB/9 and 6.2 K/9 in 46 1/3 IP.

  • Has a 1.10 ERA and 0.80 WHIP over his last 3 starts
  • Allowed 6 ER on 6 H and 2 BB with 4 K in 5 2/3 IP against St. Louis July 29

Flaherty (0-0, 5.63 ERA) makes his 4th start. He has a 2.13 WHIP, 10.1 BB/9 and 6.8 K/9 in 8 IP.

  • Threw 102 pitches in his final rehab start and will not be on a pitch limit
  • In 5 rehab starts: 20 IP, 21 H, 8 ER, 7 BB and 25 K

Nationals at Cardinals odds and lines

Odds provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 9 a.m. ET.

  • Money line (ML): Nationals +210 (bet $100 to win $210) | Cardinals -270 (bet $270 to win $100)
  • Run line (RL)/Against the spread (ATS): Nationals +1.5 (+102) | Cardinals -1.5 (-125)
  • Over/Under (O/U): 7.5 (O: -130 | U: +105)

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Nationals at Cardinals picks and predictions

Prediction

Cardinals 5, Nationals 3

Money line

This is a dangerous game to handicap because the Cards are heavy favorites, and Flaherty hasn’t been right all season. He missed the first half, and on his way back, he seemingly rushed his return and wasn’t effective before re-injuring the shoulder.

The good news for the Cards is their bullpen is rested. We’re staying away from the ML and First 5, though. The Cards have scored 5 or more runs in 7 of 10 games, and they’ll probably need to do so again Monday.

Take the CARDINALS OVER 4.5 TOTAL RUNS (-130).

Run line/Against the spread

The Nats got one from the Cards back in D.C. in July, but that was a sloppy game with a lot of walks and a Cardinals bullpen implosion. The other 2 games weren’t close, and the Nats hadn’t traded OF Juan Soto and 1B Josh Bell yet.

Take the CARDINALS -1.5 (-125).

Over/Under

Flaherty is going to give up some runs. Sanchez is going to give up runs. The Nats scored 7 runs each of the last 2 days, and the Cards have scored 5 or more runs in 7 of 10. St. Louis is 6-3-1 O/U the last 10.

This one should go OVER 7.5 (-130).

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Gannett may earn revenue from Tipico for audience referrals to betting services. Tipico has no influence over nor are any such revenues in any way dependent on or linked to the newsrooms or news coverage. See Tipico.com for Terms and Conditions. 21+ only. Gambling problem? Call 1-800-GAMBLER (NJ), 1-800-522-4700 (CO).

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Washington Nationals at St. Louis Cardinals odds, picks and prediction

Analyzing Monday’s Washington Nationals at St. Louis Cardinals odds and lines, with MLB picks and predictions.

The Washington Nationals (1-5) are visiting the St. Louis Cardinals (5-4) Monday for Game 1 of a three-game set at Busch Stadium. First pitch is scheduled for 7:45 p.m. ET. Let’s analyze BetMGM Sportsbook‘s lines around the Nationals vs. Cardinals odds with MLB picks and predictions.

Washington was swept 3-0 by the reigning World Series champion Los Angeles Dodgers and was shut out in two of those games. St. Louis lost back-to-back games—allowing 9 runs in each—against the NL Central rival Milwaukee Brewers to drop its previous series 2-1.

RHP Erick Fedde (0-1) makes his second start for the Nationals. He was smacked around in a 7-6 Nationals loss to the Atlanta Braves Wednesday. He lasted only 1 2/3 IP, giving up 5 earned runs on 6 hits and 3 walks with just 1 strikeout.

RHP John Gant (0-0) is on the mound for the Cardinals in his second start of the season and since 2018. He pitched 4 innings with only 1 unearned run allowed, while allowing 4 hits, striking out 4 and walking 3 in St. Louis’ 4-2 win over the Miami Marlins last week.

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Nationals at Cardinals odds, lines, picks and prediction

MLB odds courtesy of BetMGM; access USA TODAY Sports for a full list. Odds last updated at 3:05 p.m. ET.

  • Money line: Nationals +125 (bet $100 to win $125) | Cardinals -155 (bet $155 to win $100)
  • Against the spread/ATS: Nationals +1.5 (-150) | Cardinals -1.5 (+125)
  • Over/Under: 8.5 (O: -110 | U: -110)

Prediction

Cardinals 7, Nationals 5

Money line (ML)

PASS with a “lean” on the Cardinals (-145) because I think St. Louis is the right side but the money line is a little too expensive.

Also, I have faith the Nationals will have a good season and their 1-5 record has a lot to do with playing the teams that played for the 2020 NL pennant, which keeps me away from the Cardinals’ money line.

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Run line/Against the spread (ATS)

April has been Gant’s best month throughout his career; he is 4-0 with a 2.08 ERA, 0.92 WHIP, 35 K and 13 BB in 1 start and 21 relief appearances in March and April.

Since the beginning of 2019, Statcast grades Fedde in the bottom-third of the majors in many advanced pitching metrics including K%, Whiff% and xwOBA.

Furthermore, Fedde had a plus-5 ERA in spring training and was teed off on last week. The outing brought his career April ERA to 7.94 but in only two appearances.

BET CARDINALS -1.5 (+125) for .75 unit.

Over/Under (O/U)

Slight “LEAN” to the OVER 8.5 (-110) for a quarter-unit. The reason Gant is starting is due to injuries in the Cardinals rotation so he’s more of a wild card than a known quantity.

While the Nationals hitters are in the basement of the league vs. right-handed pitchers, they’ve faced quality opponents and have the fewest at-bats against righties since Washington’s first three games were postponed due to COVID-19.

The Nationals lineup could certainly get to a Cardinals pitching staff that has allowed 9 or more runs in four of their nine games this season.

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