Tottenham Hotspur vs. AC Milan odds, picks and predictions

Analyzing Wednesday’s Tottenham Hotspur vs. AC Milan odds and lines, with Champions League expert picks, predictions and best bets.

The Tottenham Hotspur battle AC Milan Wednesday in the 2nd leg of the Round of 16 with kickoff from Tottenham Hotspur Stadium set for 3 p.m. ET (Paramount+). Below, we preview Tipico Sportsbook’s lines around the Tottenham Hotspur vs. AC Milan odds, and make our best Champions League bets, picks and predictions.

Tottenham is on a 2-game losing streak, losing 1-0 on the road to the Wolves Saturday. They lost to Milan 1-0 on the road in the 1st leg on Feb. 14 and had just .5 expected goals. Tottenham is averaging 1.77 goals per game in league play and is led by F Harry Kane, who has 18 goals in 26 starts.

Milan had 1.5 expected goals in their 1-0 win against Tottenham, but have lost 5 of their last 9 games throughout all competitions and are coming off a 2-1 road loss to Fiorentina. Milan averages 1.68 goals per game and sits 5th in Serie A. They are led by F Rafael Leao, who has 8 goals and 6 assists in 23 games.

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Tottenham Hotspur vs. AC Milan odds

Provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Tuesday at 10:57  p.m. ET.

  • Moneyline: Tottenham Hotspur -110 (bet $110 to win $100) | AC Milan +360 (bet $100 to win $320) | Draw +260
  • Over/Under: 2.5 (O: +115 | U: -135)

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Tottenham Hotspur vs. AC Milan picks and predictions

Prediction

Tottenham Hotspur 2, AC Milan 1

Moneyline (ML)

BET TOTTENHAM HOTSPUR (-110).

Tottenham has been especially strong at home in league play, posting 9 wins and 4 losses, having yet to draw.

That same success carried over to the group stage round where they had 2 wins and a draw in 3 home matches. They have won 3 straight home games and 4 of their last 5 throughout all competitions.

Milan has lost 3 of their last 4 road matches. They will likely be down attacking mid Brahim Diaz as well which could be a blow to Milan’s ability to create in the attacking third.

Over/Under (O/U)

LEAN OVER 2.5 (+115).

Tottenham is set to get M Pierre-Emile Hojbjerg back, and he could aid their ability to transition. Tottenham also have high-level finishers able to get through the Milan defense, which hasn’t been great for much of the season.

Both defenses allow more than a goal per game while both offenses average more than 1.5 goals per game. The familiarity after playing last month should aid offenses in breaking down defenses as well.

For a smaller unit, back the OVER 2.5 (+115).

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