Houston Texans at Buffalo Bills odds, picks and prediction

Analyzing Sunday’s Houston Texas at Buffalo Bills odds and lines, with expert NFL picks, predictions and best bets.

The Houston Texans (1-2) visit the Buffalo Bills (2-1) for a 1 p.m. ET kickoff at Highmark Stadium Sunday of Week 4. Below, we look at the Texans vs. Bills odds and lines, and make our best NFL picks, predictions and bets.

The Texans will look to even up their record against the mighty Bills offense following a Thursday Night Football loss to the Carolina Panthers in Week 3.

Bills QB Josh Allen had a rough start to the season with 3 touchdowns through 2 games but the fourth-year quarterback went for 4 touchdowns and 358 yards last week against the Washington Football Team. Without much of a run game, Allen will again be called on to make plays for Buffalo.

The Texans will look to WR Brandin Cooks and RB Mark Ingram for production. Rookie QB Davis Mills will again start with veteran QB Tyrod Taylor still injured. Mills had 168 yards and a touchdown against the Panthers.

Texans at Bills odds, spread and lines

Odds provided by Tipico Sportsbook; access USA TODAY Sports’ betting odds for a full list. Lines last updated Saturday at 4:40 p.m. ET.

  • Money line: Texans +850 (bet $100 to win $850) | Bills -1800 (bet $1,800 to win $100)
  • Against the spread (ATS): Texans +17.5 (-108) | Bills -17.5 (-112)
  • Over/Under (O/U): 46.5 (O: -117 | U: -103)

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Texans at Bills key injuries

Texans

  • WR Danny Amendola (thigh) out
  • DB Terrance Mitchell (concussion, illness) questionable
  • RB Scottie Phillips (illness) out
  • LB Garrett Wallow (illness) questionable

Bills

  • S Jordan Poyer (ankle) out
  • OL Jon Feliciano (illness) out
  • CB Taron Johnson (groin) questionable
  • DE Efe Obaba (ankle) questionable

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Texans at Bills odds, lines, predictions and picks

Prediction

Bills 31, Texans 16

Money line

PASS on the money line. While Buffalo is at home and should come out on top, there’s no doubt that passing on a -1800 line is the right move.

There’s no reason to bet 18 times your potential return. All these players are paid to play football at a high level and upsets happen.

Against the spread

“LEAN” to the TEXANS +17.5 (-108) as the better value.

Mills, once he got comfortable in the offense and playing at the NFL level last week, started to move the ball. With veterans in the backfield and out wide, the Texans should be able to at least push the Bills early.

The Texans haven’t lost by more than 15 points, even while playing tough opponents in the Panthers and Cleveland Browns. With Poyer’s absence for the Bills the underdogs covering seems likely.

Over/Under

BET on the OVER 46.5 (-117) as Allen is starting to heat up.

With his struggles, the Bills went Over the projected line just once through three games. The Texans hit the Over in two of three contests.

Expect a big day from Allen against a Texans defense that gave up over 300 yards to Panthers QB Sam Darnold last week.

Mills is also getting more comfortable in the pocket, which may allow the Texans to consistently get in scoring position.

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