The Pittsburgh Steelers (1-3) and Buffalo Bills (3-1) meet Sunday at Highmark Stadium. Kickoff is set for 1 p.m. ET (CBS). Below, we analyze Tipico Sportsbook‘s lines around the Steelers vs. Bills odds, and make our expert NFL picks and predictions.
Steelers rookie QB Kenny Pickett played in his 1st NFL game in a 24-20 loss to the New York Jets last Sunday. Pickett threw for 120 yards and 3 INTs on 10-of-13 passing as Pittsburgh failed to cover as a 3-point favorite.
Pittsburgh is 1-3-1 against the spread (ATS) in its last 5 games.
Bills K Tyler Bass made a game-winning 21-yard FG in a 23-20 win at the Baltimore Ravens last Sunday. QB Josh Allen finished with 213 yards, 1 passing TD and 1 INT and ran for a score.
Buffalo is 9-1-2 ATS vs. teams with a losing record.
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Steelers at Bills odds
Provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 12:01 a.m. ET.
- Moneyline (ML): Steelers +650 (bet $100 to win $650) | Bills -1000 (bet $1,000 to win $100)
- Against the spread (ATS): Steelers +13.5 (-103) | Bills -13.5 (-117)
- Over/Under (O/U): 45.5 (O: -108 | U: -112)
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Steelers at Bills injuries
Steelers
- S Terrell Edmunds (concussion) out
- CB Cameron Sutton (hamstring) questionable
- CB Ahkello Witherspoon (hamstring) out
Bills
- CB Christian Benford (hand) out
- WR Jamison Crowder (ankle) out
- OL Tommy Doyle (knee) out
- LB Tremaine Edmunds (hamstring) questionable
- S Micah Hyde (neck) out
- TE Dawson Knox (foot) out
- WR Jake Kumerow (ankle) out
- WR Isaiah McKenzie (concussion) questionable
- DL Ed Oliver (ankle) questionable
- DL Jordan Phillips (hamstring) questionable
- S Jordan Poyer (undisclosed) out
- CB Tre’Davious White (knee) out
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Steelers at Bills picks and predictions
Prediction
Bills 31, Steelers 10
Moneyline
PASS.
Bills (-1000) will hit, but the price is too high. The spread and the total provide better opportunities.
Against the spread
Bet BILLS -13.5 (-117).
Pittsburgh coach Mike Tomlin has never been this big of an underdog ATS. This is not an opportunity for Steelers bettors, as the Bills have a Mike Tyson knockout quality. Expect Buffalo to win by margin vs. a vulnerable Pittsburgh team.
Over/Under
Bet UNDER 45.5 (-112).
The Under is 6-1 in their last 7 meetings and 3-1 in Buffalo’s last 4 games. Pittsburgh should struggle to score Sunday in Pickett’s first start and help the Under hit.
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