First look: San Francisco 49ers at Minnesota Vikings odds and lines

Looking at Sunday’s San Francisco 49ers at Minnesota Vikings Week 2 NFL odds, lines and trends. Here’s what you need to know.

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The San Francisco 49ers (1-0) and the Minnesota Vikings (1-0) meet in  Week 2 at U.S. Bank Stadium in Minneapolis. Kickoff is scheduled for 1 p.m. ET (CBS). Below, we look at 49ers vs. Vikings odds from BetMGM Sportsbook’s NFL odds before making our expert NFL picks and predictions later in the week.

The 49ers were without RB Christian McCaffrey for Week 1 due to Achilles’ and calf injuries, but RB Jordan Mason stepped in for his 1st NFL start, and his 1st NFL 100-yard game. Mason ended up with 147 rushing yards and a score in a 32-19 victory over the New York Jets, which was a Scorigami, by the way.

There are reports McCaffrey might sit again in Week 2 due to the artificial turf at U.S. Bank Stadium, so that’s something to watch during the week.

The Vikings paddled the hapless New York Giants 28-6 on the road Sunday in their opener, as QB Sam Darnold tossed 2 TDs, including 1 to superstar WR Justin Jefferson. Unlike the 49ers, the Vikings cashed low on the total in Week 1. Now, Darnold makes his home debut for the Vikings against his 2023 team.

49ers at Vikings odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list of NFL odds. Lines last updated Tuesday at 6:11 a.m. ET.

  • Moneyline (ML): 49ers -275 (bet $275 to win $100) | Vikings +220 (bet $100 to win $220)
  • Against the spread (ATS): 49ers -6 (-110) | Vikings +6 (-110)
  • Over/Under (O/U): 45.5 (O: -110 | U: -110)

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2024 betting stats

  • ML: 49ers 1-0 | Vikings 1-0
  • ATS: 49ers 1-0 | Vikings 1-0
  • O/U: 49ers 1-0 | Vikings 0-1

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49ers vs. Vikings head-to-head

This will be the 10th meeting since 2006. Minnesota holds a 5-4 edge in the series during the span. The home side has won 7 straight meetings, with the home team also 6-0 ATS in the previous 6 in this series.

These teams met last season in the Twin Cities, with Minnesota winning 22-17 as a 6.5-point underdog as the Under (44) cashed on Oct. 23, 2023. The Under is 5-1 in the past 6 meetings, and 7-2 in the previous 9 in the series, including the past 3 battles in the Twin Cities.

The teams have played 50 times (6 in the postseason) with the 49ers ahead 25-24-1.

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For more sports betting picks and tips, check out SportsbookWire.com and BetFTW.

Follow Kevin J. Erickson on Twitter/X. Follow SportsbookWire on Twitter/X and like us on Facebook.

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First look: San Francisco 49ers at Minnesota Vikings odds and lines

Looking at Monday’s San Francisco 49ers at Minnesota Vikings Week 7 NFL odds, lines and trends. Here’s what you need to know.

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The San Francisco 49ers (5-1) and the Minnesota Vikings (2-4) meet for Monday Night Football in Week 7 at U.S. Bank Stadium in Minneapolis. Kickoff is scheduled for 8:15 p.m. ET (ABC/ESPN). Below, we look at 49ers vs. Vikings odds from FanDuel Sportsbook. Also see: SportsbookWire’s NFL picks and predictions.

The 49ers took their 1st loss of the season Sunday in Cleveland, falling by a 19-17 score to the Browns. Rookie PK Jake Moody misfired on a a 41-yard game-winning field goal attempt with :06 left in regulation, as the Browns won outright as an 8.5-point underdog.

To make matters worse, the Niners saw both RB Christian McCaffrey (oblique, ribs) and WR Deebo Samuel (shoulder) exit early, and each player is a question mark for Week 7. At least they have an extra day to heal.

The 49ers saw a 3-game cover streak snapped, while the total pushed at most shops. The Over is still 3-1-1 in the past 5 games overall, while going 1-1-1 in 3 outings on the road.

The Vikings scratched out a 19-13 victory in the rain and wind in Chicago, covering a 3-point number. Minnesota has done its best work on the road, going 2-1 SU and 2-0-1 ATS. At home, the Vikings are 0-3 SU/ATS. The Under cashed Sunday, and it is 5-1 overall, including 3-0 at home.

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49ers at Vikings odds

Provided by FanDuel Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Monday at 11:51 a.m. ET.

  • Moneyline (ML): 49ers -300 (bet $300 to win $100) | Vikings +240 (bet $100 to win $240)
  • Against the spread (ATS): 49ers -7 (-110) | Vikings +7 (-110)
  • Over/Under (O/U): 44 (O: -110 | U: -110)

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2023 betting stats

  • ML: 49ers 5-1 | Vikings 2-4
  • ATS: 49ers 4-2 | Vikings 2-3-1
  • O/U: 49ers 3-2-1 | Vikings 1-5

49ers at Vikings head-to-head

The last meeting in this series was Nov. 28, 2021, in Santa Clara, as the 49ers won 34-26 as a 4-point favorite. The Over (49) cashed in that matchup, snapping a 4-game Under streak in the series.

San Francisco has won 3 of the past 4 meetings outright, while also covering 3 of the past 4 in the series. The home team has won and covered 5 straight meetings, too, with the home team winning 6 in a row. The road team last won outright when the Vikings won 27-7 at Candlestick Park on Dec. 9, 2007.

This will be the 50th meeting with the 49ers ahead 25-23-1, including 5-1 in  the postseason.

Play our free daily Pick’em Challenge and win! Play now!

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For more sports betting picks and tips, check out SportsbookWire.com and BetFTW.

Follow Kevin J. Erickson on Twitter/X. Follow SportsbookWire on Twitter/X and like us on Facebook.

Access more NFL coverage:

TheHuddle Fantasy Football | BearsWire | BengalsWire | BillsWire | BroncosWire | BrownsWire | BucsWire | CardsWire | ChargersWire | ChiefsWire | ColtsWire | CommandersWire | CowboysWire | DolphinsWire | EaglesWire | FalconsWire | GiantsWire | JaguarsWire | JetsWire | LionsWire | NinersWire | PackersWire | PanthersWire | PatriotsWire | RaidersWire | RamsWire | RavensWire | SaintsWire | SeahawksWire | SteelersWire | TexansWireTitansWire | VikingsWire | DraftWire | TouchdownWire | ListWire

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