San Francisco 49ers vs. Green Bay Packers odds lines money line against the spread Over Under

First look: San Francisco 49ers at Green Bay Packers odds and lines

Looking at Sunday’s San Francisco 49ers at Green Bay Packers Week 12 NFL odds, lines and trends. Here’s what you need to know.

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The San Francisco 49ers (5-5) meet the Green Bay Packers (7-3) in a Sunday contest at Lambeau Field. Kickoff is scheduled for 4:25 p.m. ET (FOX). Let’s analyze BetMGM Sportsbook’s NFL odds around the 49ers vs. Packers odds, and make our expert NFL picks and predictions.

The 49ers will head to Wisconsin looking for their third straight road win, but on Sunday they fell 20-17 to the visiting Seattle Seahawks. The favored-by-6 49ers had a lead late, but Seahawks QB Geno Smith ran in a 12-yarder with 12 seconds left to cap a game-winning, 11-play, 80-yard drive.

The Packers ran their record since the beginning of October to 5-1 with a 20-19 win at the Chicago Bears Sunday. A QB Jordan Love touchdown at the 2:59 mark of the fourth quarter helped the Packers (-6) to the win. Green Bay blocked a would-be game-winning field goal as time expired.

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49ers at Packers odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list of NFL odds. Lines last updated Monday at 7:23 a.m. ET.

Moneyline: 49ers +100 (bet $100 to win $100) | Packers -120 (bet $120 to win $100)
Against the spread (ATS): 49ers +1.5 (-110) | Packers -1.5 (-110)
Over/Under (O/U): 47.5 (O: -110 | U: -110)

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2024 betting stats

ML: 49ers 5-5 | Packers 7-3
ATS: 49ers 4-6 | Packers 4-6
O/U: 49ers 5-5 | Packers 4-5-1

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49ers vs. Packers head-to-head

The last 2 San Francisco-Green Bay games have been playoff tilts, and the 49ers won both. Overall, their series includes 10 postseason meetings, and the Packers lead the series 38-34-1.

Since 2019, the 49ers are 4-2 straight up and 3-3 ATS. The last 3 meetings have been 1-score football games.

Since 2015, each side has 4 SU wins and 4 ATS wins. And the O/U has also seen a 4-4 split.

The last 10 series games at Lambeau Field have netted 7 Green Bay wins and 3 for San Francisco. Over that span, ATS betting has produced a 4-4-2 split. The Over has a 6-4 edge across the last 10 games at Green Bay.

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San Francisco 49ers at Green Bay Packers odds, picks and prediction

Analyzing Saturday’s San Francisco 49ers at Green Bay Packers NFC Divisional Round odds and lines, with expert NFL picks, predictions and best bets.

The San Francisco 49ers (11-7) visit the Green Bay Packers (13-4) for an NFC Divisional Round playoff game at Lambeau Field Saturday. Kickoff is scheduled for 8:15 p.m. ET (on FOX). Below, we look at the 49ers vs. Packers odds and lines, and make our best NFL picks, predictions and bets.

The 49ers beat the Dallas Cowboys 23-17 in their NFC Wild Card game. They fired out to a 13-0 lead with 9:40 to go in the second quarter, and led 23-7 heading to the fourth quarter before holding on for the win. San Francisco covered the spread as a 3.5-point underdog and the Under (51) hit.

The Packers were the lone NFC team on a bye, resting bumps and bruises after securing the No. 1 overall seed. Green Bay enters 1-3 against the spread (ATS) across the past four games, while cashing the Over in six of the previous seven outings.

Also see: All Divisional Round odds and lines

49ers at Packers odds, spread and lines

Odds provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 5:17 a.m. ET.

Money line: 49ers +190 (bet $100 to win $190) | Packers -240 (bet $240 to win $100)
Against the spread (ATS): 49ers +5.5 (-112) | Packers -5.5 (-108)
Over/Under (O/U): 47.5 (O: -103 | U: -117)

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49ers at Packers key injuries

49ers

DL Nick Bosa (concussion) questionable
CB Ambry Thomas (knee) questionable
DL Jordan Willis (ankle) questionable

Packers

CB Jaire Alexander (shoulder) questionable
OT David Bakhtiari (knee) questionable
WR Marquez Valdes-Scantling (back) doubtful

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49ers at Packers odds, lines, predictions and picks

Prediction

Packers 31, 49ers 17

Money line

Green Bay (-240) will cost you 2.4 times your potential return. That’s too risky for a playoff game, even though confidence is high that the Packers will win on their home field.

AVOID.

Against the spread

GREEN BAY -5.5 (-108) is the play. The top-seeded Packers are well rested after two weeks since their last game. Some key players played sparingly in Week 18, too.

This is a double-edged sword as too much rest can lead to a little bit of rust, while the 49ers enter with some momentum after a thrilling win in Dallas last week.

Still, Green Bay has a powerful offense, and it is at home in the frozen tundra. Look for a comfortable Packers win in front of the Cheeseheads.

Over/Under

The lean is to the OVER 47.5 (-103), ever so slightly. While yes, the Under has hit in five of the past six games for the 49ers, and four of the past five against teams with a winning record, it’s the opposite for the Packers.

Green Bay has hit the Over in six of the past seven overall, and five of the past six as a favorite. The Over is also a perfect 7-0 in the past seven Green Bay playoff games, including 4-0 in the past four at home.

A small-unit play on OVER 47.5 (-103) is the way to go.

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First look: San Francisco 49ers at Green Bay Packers odds and lines

Looking at Saturday’s San Francisco 49ers at Green Bay Packers Divisional Round NFL odds, lines and trends. Here’s what you need to know.

The San Francisco 49ers and Green Bay Packers clash in an NFC Divisional Round playoff game Saturday. The showdown at Lambeau Field is slated for an 8:15 p.m. ET kickoff. Below, we look at the 49ers vs. Packers odds and lines; check back for our NFL picks and predictions.

San Francisco defeated the Dallas Cowboys 23-17 in a wild-card game. The 49ers leveraged 14 Dallas penalties in clocking their third consecutive victory and scored 23 of the game’s first 30 points. San Francisco went 3-5 over their first eight games this season but are 8-2 since.

The Packers earned a bye in the Wild Card Round by finishing as the top seed in the NFC. Green Bay is 5-1 over its last six games and tallied 30 or more points in five of those games. Green Bay is 8-0 at home this season; six of those eight games were decided by two-or-more possessions.

Also see: All Divisional Round odds and lines

49ers at Packers odds, spread and lines

Odds provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Tuesday at 8:28 a.m. ET.

Money line: 49ers +200 (bet $100 to win $200) | Packers -250 (bet $250 to win $100)
Against the spread (ATS): 49ers +5.5, -108 (bet $108 to win $100) | Packers -5.5, -112 (bet $112 to win $100)
Over/Under (O/U): 47.5, O: -112 (bet $112 to win $100) | U: -108 (bet $108 to win $100)

Also see: Betting 101

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2021-22 betting stats:

ML: 49ers 11-7 | Packers 13-4
ATS: 49ers 10-8 | Packers 12-5
O/U: 49ers 8-10 | Packers 8-9

49ers at Packers head-to-head

The ‘Niners fell 30-28 at home to the Packers Sept. 26.

The two sides leapfrogged each other twice in the final 40 seconds. San Francisco took a 28-27 lead on a touchdown with 37 seconds left but Green Bay got a PK Mason Crosby 51-yard field goal as time expired for the victory. Overall, the Packers outgained the 49ers 353 yards to 298 and were the beneficiaries of a plus-2 in the turnover battle.

Green Bay has beaten San Francisco each of the last two seasons (34-17 in 2020) and has won four of six games against the ‘Niners since 2015 (3-3 ATS). The Packers lead the all-time series 38-32-1.

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