San Francisco 49ers at Chicago Bears odds, picks and prediction

Analyzing Sunday’s San Francisco 49ers at Chicago Bears odds and lines, with expert NFL picks, predictions and best bets.

The San Francisco 49ers (2-4) come off their bye to face the Chicago Bears (3-4) on the road in Week 8. They kick off their game Sunday at 1 p.m. ET at Soldier Field. Below, we look at the 49ers vs. Bears odds and lines, and make our best NFL picks, predictions and bets.

The 49ers have lost four straight games after a 2-0 start. They have struggled to take care of the football as they have turned the ball over nine times in the four losses. They have been inconsistent offensively, twice gaining more than 440 yards and twice gaining fewer than 300.

The Bears have lost their last two games and have struggled offensively. They rank 30th in the NFL averaging just 14.4 points per game. Rookie QB Justin Fields has thrown only two touchdown passes and has six interceptions.

49ers at Bears odds, spread and lines

Odds provided by Tipico Sportsbook; access USA TODAY Sports’ betting odds for a full list. Lines last updated Saturday at 10:30 a.m. ET.

  • Money line: 49ers -205 (bet $205 to win $100) | Bears +165 (bet $100 to win $165)
  • Against the spread (ATS): 49ers -3.5 (-112) | Bears +3.5 (-108)
  • Over/Under (O/U): 39.5 (O: -108 | U: -112)

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49ers at Bears key injuries

49ers

  • DE Dee Ford (concussion) doubtful
  • LT Trent Williams (ankle, elbow) questionable
  • Jaquiski Tartt (knee) out

Bears

  • OLB Khalil Mack (foot) out
  • Tashaun Gipson (hip) questionable
  • DL Akiem Hicks (groin) questionable

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49ers at Bears odds, lines, predictions and picks

Prediction

49ers 24, Bears 17

Money line

The 49ers should win this game. Their defense has questions against the pass, but Fields has not been able to exploit anyone. The Bears offense struggles. They have scored 14 or fewer points in four of their seven games. They have four games with fewer than 280 total yards.

The 49ers have had time to prepare an offensive plan with their Week 7 bye and the 49ers are 24-11 when QB Jimmy Garoppolo starts in his career.

Take the 49ERS (-205).

Against the spread

Only the Washington Football Team has a worse record against the spread than the 49ers’ 1-5 ATS mark.

The Bears, even with their offensive struggles, are 3-4 ATS this season.

However, with a fairly even spread on both sides.

I know there isn’t a lot of love for Garoppolo, but he does give the 49ers a better shot of winning.

Take the 49ERS -3.5 (-112).

Over/Under

Six of the Bears’ seven games have stayed Under the projected total.

The 49ers are 3-3 O/U this season.

I expect the 49ers to play better than they did last week and for the Bears to continue to struggle to score points.

This is the lowest O/U total in the league this week. Take OVER 39.5 (-108).

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