Cincinnati Reds at Chicago Cubs odds, picks and predictions

Analyzing Wednesday’s Cincinnati Reds at Chicago Cubs odds and lines, with MLB expert picks and predictions.

The Cincinnati Reds (26-47) take on the Chicago Cubs (28-46) Wednesday in the 2nd of a 3-game series in Chicago. First pitch is 8:05 p.m. ET at Wrigley Field. Let’s analyze Tipico Sportsbook‘s lines around the Reds vs. Cubs odds with MLB picks and predictions.

The Reds lead the season series 3-2.

The Reds took the series opener 5-3 behind starter Juan Castillo’s 6 scoreless innings and 2B Jonathan India’s 2nd home run of the year. They have won 2 in a row and 3 of their last 4 games.

The Cubs lost for the 15th time in their last 20 games. They have, though, alternated wins and losses in their last 6.

Reds at Cubs projected starters

RHP Hunter Greene vs. LHP Justin Steele

Greene (3-8, 5.66 ERA) makes his 15th start. He has a 1.36 WHIP, 3.9 BB/9 and 11.3 K/9 in 70 IP.

  • Allowed 5 runs on 5 hits in 5 innings against the Cubs on May 26,  but got the victory as the Reds won that game 20-5.
  • The Reds are 3-11 when Greene starts and have lost his last 3 outings and 4 of the last 5.

Steele (2-5, 4.59 ERA) makes his 15th start. He has a 1.45 WHIP, 4.0 BB/9 and 8.5 K/9 in 64 2/3 IP.

  • Was hammered in his lone start against the Reds, the 20-5 loss. He gave up 7 runs on 7 hits in only 2 innings.
  • Has pitched much better at home. He’s 0-2 with a 7.29 ERA and 1.71 WHIP on the road while at Wrigley Field he’s 2-3 with a 3.30 ERA and 1.33 WHIP.

Reds at Cubs odds and lines

Odds provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 10:42 a.m. ET.

  • Money line (ML): Reds +115 (bet $100 to win $115) | Cubs -140 (bet $140 to win $100)
  • Run line (RL)/Against the spread (ATS): Reds +1.5 (-190) | Cubs -1.5 (+155)
  • Over/Under (O/U): 7.5 (O: -120 | U: -105)

Exclusive USA TODAY Network offer: Deposit $10 or more, get $200 in instant bet credits at Tipico Sportsbook! New customer offer in CO and NJ. 21+, see Tipico.com for Terms and Conditions. Place your legal, online sports bets at Tipico. Let’s make this interesting. Bet now!

Reds at Cubs picks and predictions

Prediction

Cubs 6, Red 4

Money line

Only 2 teams in the majors have fewer than the Reds’ 14 road wins this season, although they have won 6 of their last 8 games away from home.

The Cubs are 13-26 at Wrigley Field this year. After a 10-game losing streak, they have gone 5-6 and are 3-3 in their last 6 games, alternating wins at losses. They lost the series opener Tuesday.

What makes the difference Wednesday is how Steele has pitched at home. He is 2-3 with a 3.30 ERA in 9 home starts.

Take the CUBS (-140),

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Run line/Against the spread

Only 4 teams are worse than the Reds’ 33-40 ATS mark. The Cubs are 36-38 ATS overall. The Cubs are 16-23 ATS at home, while the Reds are 20-18 ATS on the road.

There has only been one 1-run game between the 2 teams this season.

Eight of the Cubs’ last 13 games have been by at least 2 runs.

Seven of the 11 losses the Reds have had with Greene starting have been by 2 or more runs.

This is not high confidence, but the value of this bet makes it worth the play. Take the CUBS -1.5 (+155).

Over/Under

Four of the 5 games between the Cubs and Reds this season have had 8 or more runs, including Tuesday’s opener.

Fourteen of the Reds’ last 15 games and 7 of the Cubs’ last 8 have had 8 or more runs.

Take OVER 7.5 (-120).

Bet legally online with a trusted partner: Tipico Sportsbook, Sportsbook Wire’s official sportsbook partner in CO, NJ and soon IA. Bet now!

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Cincinnati Reds at Chicago Cubs odds, picks and predictions

Analyzing Tuesday’s Cincinnati reds at Chicago Cubs odds and lines, with MLB expert picks and predictions.

The Cincinnati Reds (25-47) face the Chicago Cubs (28-45) in a 3-game series starting Tuesday with first pitch set for 8:05 p.m. ET at Wrigley Field. Let’s analyze Tipico Sportsbook‘s lines around the Reds vs. Cubs odds with MLB picks and predictions.

Season series: Tied 2-2

The Reds ended a 7-game skid last weekend when they took 2 of 3 from the Giants in San Francisco.

The Cubs are coming off a 3-4 road trip. They won 2 of 3 last weekend against the rival St. Louis Cardinals.

Reds at Cubs projected starters

RHP Luis Castillo vs. RHP Keegan Thompson

Castillo (2-4, 3.71 ERA) makes his 10th start. He has a 1.14 WHIP, 3.2 BB/9 and 8.6 K/9 in 51 IP.

  • Won May 25 start vs Cubs with 5 IP, 2 ER, 4 H, 1 BB and 6 K.
  • In 7 career starts at Wrigley Field he has a 4.14 ERA and 1.43 WHIP with 35 K and 18 BB in 37 IP.

Thompson (7-2, 3.10 ERA) makes his 17th appearance (9th start). He has a 1.15 WHIP, 3.1 BB/9 and 8.1 K/9 in 61 IP.

  • His skills have been a lot better as a reliever than as a starter, but he is coming off 2 of his best starts. In those outings he surrendered just 1 ER in 12 IP with a 16/3 K/BB, but in his previous 2 the total was 10 ER in 3 2/3 IP.
  • Has fared much better at home than on the road this season. At Wrigley, he has a 9.5 K/9 and 1 HR allowed while he’s sporting a 5.40 ERA and 6.1 K/9 in away games.

Reds at Cubs odds and lines

Odds provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 9:44 a.m. ET.

  • Money line (ML): Reds -103 (bet $103 to win $100) | Cubs -117 (bet $117 to win $100)
  • Run line (RL)/Against the spread (ATS): Reds -1.5 (+155) | Cubs +1.5 (-190)
  • Over/Under (O/U): 8.5 (O: -130 | U: +105)

Exclusive USA TODAY Network offer: Deposit $10 or more, get $200 in instant bet credits at Tipico Sportsbook! New customer offer in CO and NJ. 21+, see Tipico.com for Terms and Conditions. Place your legal, online sports bets at Tipico. Let’s make this interesting. Bet now!

Reds at Cubs picks and predictions

Prediction

Reds 6, Cubs 4

Money line

Thompson has put up a 4.34 ERA in his 8 starts along with a 7.7 K/9 and 1.5 HR/9. The Reds have scored the 3rd fewest runs per game away from home this season, but have been much better lately with 5.3 per game in their last 7 road contests.

The Cubs have the 2nd worst home record in all of baseball at 13-25 and Cincinnati has the pitching edge in this one. Back the REDS -103.

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Run line/Against the spread

Chicago’s last 9 home losses have been by multiple runs and the Cincinnati bats should get to Thompson with the wind expected to be blowing out at about 10 mph. The odds are good enough here for a small play on REDS -1.5 (+155).

Over/Under

Thompson has been up and down as a starter and Castillo, who has allowed 3 ER or more in 3 of his last 4 starts, can’t be expected to completely shut the Cubs down. The offenses should get just enough help from the weather to push this total OVER 8.5 (-130).

Bet legally online with a trusted partner: Tipico Sportsbook, Sportsbook Wire’s official sportsbook partner in CO, NJ and soon IA. Bet now!

If you’re looking for more sports betting picks and tips, access all of our content at SportsbookWire.com and BetFTW, or try out our USA TODAY Parlay Calculator. Please gamble responsibly.

Follow @RuddHQ on Twitter. Follow SportsbookWire on Twitter and like us on Facebook.

Additional MLB coverage:
BaseballHQ Fantasy Baseball
BaseballPress.com: Your source for every MLB lineup

Gannett may earn revenue from Tipico for audience referrals to betting services. Tipico has no influence over nor are any such revenues in any way dependent on or linked to the newsrooms or news coverage. See Tipico.com for Terms and Conditions. 21+ only. Gambling problem? Call 1-800-GAMBLER (NJ), 1-800-522-4700 (CO), 1-800-BETS-OFF (IA).

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