Cincinnati Reds at Chicago Cubs odds, picks and predictions

Analyzing Wednesday’s Cincinnati Reds at Chicago Cubs odds and lines, with MLB expert picks and predictions.

The Cincinnati Reds (26-47) take on the Chicago Cubs (28-46) Wednesday in the 2nd of a 3-game series in Chicago. First pitch is 8:05 p.m. ET at Wrigley Field. Let’s analyze Tipico Sportsbook‘s lines around the Reds vs. Cubs odds with MLB picks and predictions.

The Reds lead the season series 3-2.

The Reds took the series opener 5-3 behind starter Juan Castillo’s 6 scoreless innings and 2B Jonathan India’s 2nd home run of the year. They have won 2 in a row and 3 of their last 4 games.

The Cubs lost for the 15th time in their last 20 games. They have, though, alternated wins and losses in their last 6.

Reds at Cubs projected starters

RHP Hunter Greene vs. LHP Justin Steele

Greene (3-8, 5.66 ERA) makes his 15th start. He has a 1.36 WHIP, 3.9 BB/9 and 11.3 K/9 in 70 IP.

  • Allowed 5 runs on 5 hits in 5 innings against the Cubs on May 26,  but got the victory as the Reds won that game 20-5.
  • The Reds are 3-11 when Greene starts and have lost his last 3 outings and 4 of the last 5.

Steele (2-5, 4.59 ERA) makes his 15th start. He has a 1.45 WHIP, 4.0 BB/9 and 8.5 K/9 in 64 2/3 IP.

  • Was hammered in his lone start against the Reds, the 20-5 loss. He gave up 7 runs on 7 hits in only 2 innings.
  • Has pitched much better at home. He’s 0-2 with a 7.29 ERA and 1.71 WHIP on the road while at Wrigley Field he’s 2-3 with a 3.30 ERA and 1.33 WHIP.

Reds at Cubs odds and lines

Odds provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 10:42 a.m. ET.

  • Money line (ML): Reds +115 (bet $100 to win $115) | Cubs -140 (bet $140 to win $100)
  • Run line (RL)/Against the spread (ATS): Reds +1.5 (-190) | Cubs -1.5 (+155)
  • Over/Under (O/U): 7.5 (O: -120 | U: -105)

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Reds at Cubs picks and predictions

Prediction

Cubs 6, Red 4

Money line

Only 2 teams in the majors have fewer than the Reds’ 14 road wins this season, although they have won 6 of their last 8 games away from home.

The Cubs are 13-26 at Wrigley Field this year. After a 10-game losing streak, they have gone 5-6 and are 3-3 in their last 6 games, alternating wins at losses. They lost the series opener Tuesday.

What makes the difference Wednesday is how Steele has pitched at home. He is 2-3 with a 3.30 ERA in 9 home starts.

Take the CUBS (-140),

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Run line/Against the spread

Only 4 teams are worse than the Reds’ 33-40 ATS mark. The Cubs are 36-38 ATS overall. The Cubs are 16-23 ATS at home, while the Reds are 20-18 ATS on the road.

There has only been one 1-run game between the 2 teams this season.

Eight of the Cubs’ last 13 games have been by at least 2 runs.

Seven of the 11 losses the Reds have had with Greene starting have been by 2 or more runs.

This is not high confidence, but the value of this bet makes it worth the play. Take the CUBS -1.5 (+155).

Over/Under

Four of the 5 games between the Cubs and Reds this season have had 8 or more runs, including Tuesday’s opener.

Fourteen of the Reds’ last 15 games and 7 of the Cubs’ last 8 have had 8 or more runs.

Take OVER 7.5 (-120).

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