Chicago Cubs at Cincinnati Reds odds, picks and predictions

Analyzing Wednesday’s Chicago Cubs at Cincinnati Reds odds and lines, with MLB expert picks, predictions and best bets.

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The Cincinnati Reds (52-55) welcome the Chicago Cubs (51-58) to Great American Ball Park Wednesday for the finale of their 3-game series. First pitch is set for 7:10 p.m. ET. Let’s analyze FanDuel Sportsbook’s lines around the Cubs vs. Reds odds and make our expert MLB picks and predictions for the best bets.

Season series: Reds lead 7-2

The Reds beat the Cubs 6-3 Tuesday and 7-1 Monday.

Those back-to-back victories came following a 2-game losing streak. Cincinnati has won 5 of its last 7 games though. It is 27-28 at home. The Reds, who sit 4th in the NL Central, are 59-48 against the spread (ATS) and are 6-1 ATS over their last 7.

The Cubs are the exact opposite, having lost the last 2 games after 2 straight wins. Chicago is 2-5 over its last 7 games, scoring 3 or fewer in every loss. The Cubs are 24-33 on the road and 3-5 in their last 8 away games.

Cubs at Reds projected starters

RHP Kyle Hendricks vs. LHP Nick Lodolo

Hendricks (2-9, 6.95 ERA) makes his 15th start. He has a 1.49 WHIP, 2.7 BB/9 and 6.3 K/9 in 80 1/3 IP.

  • Last start: No-decision, 5 IP, 6 R, 8 H, 0 BB, 4 K in 6-0 road loss to the Kansas City Royals Friday
  • 2024 away splits: 1-5, 7.49 ERA (45 2/3 IP, 38 ER), 1.45 WHIP, 11 HR, 5.3 K/9 in 10 appearances (8 starts)
  • Career vs. Reds: 8-6, 4.26 ERA (139 1/3 IP, 66 ER), 1.31 WHIP, 7.9 K/9 in 26 appearances (24 starts)

Lodolo (8-3, 3.45 ERA) makes his 17th start. He has a 1.11 WHIP, 2.6 BB/9 and 9.3 K/9 in 91 1/3 IP.

  • Last start: No-decision, 6 2/3 IP, 2 R, 5 H, 1 BB, 5 K in 3-2 road win over the Tampa Bay Rays Friday
  • 2024 home splits: 4-2, 4.05 ERA (46 2/3 IP, 21 ER), 1.39 WHIP, 6 HR, 8.3 K/9 in 9 starts
  • Career vs. Cubs: 2-1, 3.32 ERA (21 2/3 IP, 8 ER), 1.48 WHIP, 8.7 K/9 in 4 starts

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Cubs at Reds odds

Provided by FanDuel Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 6:46 a.m. ET.

  • Moneyline (ML): Cubs +126 (bet $100 to win $126) | Reds -148 (bet $148 to win $100)
  • Run line (RL)/Against the spread (ATS): Cubs +1.5 (-162) | Reds -1.5 (+134)
  • Over/Under (O/U): 9.5 (O: +100 | U: -122)

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Cubs at Reds picks and predictions

Prediction

Reds 6, Cubs 3

Moneyline

BET REDS (-148).

The Reds have dominated the season series against Chicago, and the Cubs offense has been nonexistent as of late. They have scored 3 or fewer runs in 9 of their last 11 games and have allowed 5 or more runs in 4 of those.

The Reds have scored 4 or more runs in 6 of their last 10 and have won 5 of their last 6 games at home. Cincinnati has also won consistently with Lodolo on the mound, coming out on top in 11 of his 16 appearances. It has won 7 of his last 10 starts.

Considering those trends, take REDS (-148).

Run line/Against the spread

PASS.

The Reds could be worth a play on the run line, but the better value is on the more expensive moneyline play. The Cubs are too risky and too expensive to consider as a run-line underdog.

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Over/Under

BET UNDER 9.5 (-122).

Both teams are trending toward the Under.

The Cubs have gone Under in 2 straight games and in 9 of their last 11. Chicago is 45-60-4 O/U on the season. Its offense has struggled, and there’s no reason to think it’ll perform well Wednesday.

The Reds have gone Under in 5 straight games and in 7 of their last 8, allowing 4 or fewer in 7 straight and 2 or fewer in 3 of their last 5. Couple all that together and take UNDER 9.5 (-122).

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Chicago Cubs at Cincinnati Reds odds, picks and predictions

Analyzing Sunday’s Chicago Cubs at Cincinnati Reds odds and lines, with MLB expert picks, predictions and best bets.

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The Cincinnati Reds (32-33) and Chicago Cubs (31-34) wrap up a 4-game series Sunday at Great American Ball Park. First pitch is set for 1:40 p.m. ET. Let’s analyze FanDuel Sportsbook’s lines around the Cubs vs. Reds odds and make our expert MLB picks and predictions for the best bets.

Season series: Reds lead 5-1

The Reds are going for a 4-game sweep after taking the opener 8-4, the second game 3-2 and Saturday’s contest 4-3. Cincinnati was a favorite in all 3 — at -126 Thursday, -137 Friday and -123 Sunday. The last 2 games cashed Under (9) tickets following an Over (9.5) in the opener.

Cincinnati has rolled off 7 straight wins, jumping into 2nd in the NL Central after starting the week in last place. Cincy is 5-2 against the spread (ATS) in the win streak and is 36-29 ATS on the season, according to Teamrankings.com.

The Cubs have lost 3 in a row, are 3-7 in their last 10 games and have lost 4 straight to the Reds going back to last weekend’s series at Wrigley Field. They are 31-34 ATS on the season.

Cubs at Reds projected starters

LHP Shota Imanaga vs. RHP Frankie Montas

Imanaga (5-1, 1.88 ERA) makes his 12th start. He has a 1.04 WHIP, 1.4 BB/9 and 9.4 K/9 through 62 1/3 innings.

  • Last start: No-decision, 4 1/3 IP, 1 ER (5 R), 7 H, 0 BB, 6 K in 7-6 home win over Chicago White Sox Tuesday
  • 2024 road splits: 3-1, 2.57 ERA (28 IP, 8 ER), 1.29 WHIP, 3 HR, 8.7 K/9 in 5 starts
  • First year in majors; has never faced Reds

Montas (3-4, 4.00 ERA) makes his 12th start. He has a 1.28 WHIP, 3.3 BB/9 and 7.0 K/9 through 54 innings.

  • Last start: Win, 7 IP, 0 ER, 1 H, 2 BB, 9 K in 4-1 win at Colorado Rockies Tuesday
  • 2024 home splits: 1-3, 3.34 ERA (29 2/3 IP, 11 ER), 1.18 WHIP, 1 HR, 7.0 K/9 in 6 starts
  • Never faced Cubs before

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Cubs at Reds odds

Provided by FanDuel Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 1:15 a.m. ET.

  • Moneyline (ML): Cubs -130 (bet $130 to win $100) | Reds +110 (bet $100 to win $110)
  • Run line (RL)/Against the spread (ATS): Cubs -1.5 (+116) | Reds +1.5 (-140)
  • Over/Under (O/U): 8.5 (O: -124 | U: +102)

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Cubs at Reds picks and predictions

Prediction

Cubs 5, Reds 4

Moneyline

BET CUBS (-130).

The Reds have lost 5 of Montas’ last 6 starts, but they did win his last outing. Overall, Cincinnati is just 4-7 in his starts this season. Meanwhile, Imanaga has been an extremely strong option for the Cubs, who are 9-2 in his 11 starts this season.

This prediction is based on the Cubs starting the better pitcher. Despite the Reds’ 7-game win streak, they are still just 15-16 following a win.

BACK CUBS (-130).

Run line/Against the spread

PASS.

The Cubs on the moneyline are the safer option here. They have some value as run-line favorites (-1.5, +116), but considering how well the Reds are playing, taking the Cubs to just win and not cover is the smarter option.

Over/Under

BET OVER 8.5 (-124).

The Reds are 3-2 O/U in Montas’ last 5 starts and are 3-3 O/U in their last 6 games.

The Cubs are 3-2 O/U in their last 5 games and are 8-2-1 O/U in their last 11. Chicago has gone Over in Imanaga’s last 2 starts as well, giving up a combined 16 runs while scoring 13 in those 2.

Given those recent pitching trends, BET OVER 8.5 (-124).

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Cincinnati Reds at Chicago Cubs odds, picks and predictions

Analyzing Saturday’s Cincinnati Reds at Chicago Cubs odds and lines, with MLB expert picks, predictions and best bets.

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The Chicago Cubs (28-30) welcome the Cincinnati Reds (25-32) to Wrigley Field Saturday for the 2nd game of their 3-game series. First pitch is set for 7:15 p.m. ET (FOX). Let’s analyze FanDuel Sportsbook’s lines around the Reds vs. Cubs odds and make our expert MLB picks and predictions for the best bets.

Season series: Reds lead 1-0

The Reds kicked off the series strong with a 5-4 win Friday. A 2-run HR by SS Santiago Espinal in his lone at-bat took Cincinnati from down 3-2 to up 4-3, and it never lost the lead after.

The Reds snapped a 2-game losing streak with the victory. That losing streak came on the back of a 4-game winning streak in which 3 of those wins came in a sweep over the Los Angeles Dodgers. Cincinnati is 6-4 over its last 10 yet still sits last in the NL Central. It is 30-27 against the spread (ATS) on the season.

The Cubs continued their losing ways Friday, having now lost 3 in a row. Chicago has struggled mightily over the past two weeks, losing 8 of its last 9 with 6 of those defeats coming against divisional opponents. It sits 3rd in the NL Central and is 28-30 ATS.

Reds at Cubs projected starters

RHP Hunter Greene vs. LHP Justin Steele

Greene (3-2, 3.06 ERA) makes his 12th start. He has a 1.14 WHIP, 3.5 BB/9 and 9.9 K/9 through 64 2/3 IP.

  • Last start: Win, 6 IP, 1 ER, 5 H, 1 BB, 5 K in a 3-1 home win over the Los Angeles Dodgers Saturday
  • 2024 road splits: 2-0, 1.85 ERA (24 1/3 IP, 5 ER), 14 H, 1 HR, 7 BB, 27 K in 4 starts
  • Career vs. Cubs: 3-1, 3.43 ERA (21 IP, 8 ER), 0.86 WHIP, 12.9 K/9 in 4 starts

Steele (0-2, 4.45 ERA) makes his 7th start. He has a 1.05 WHIP, 1.9 BB/9 and 8.6 K/9 through 32 1/3 IP.

  • Last start: No-decision, 7 IP, 0 ER, 3 H, 1 BB, 8 K in 5-1 road loss to the Milwaukee Brewers Monday
  • 2024 home splits: 0-2, 4.86 ERA (16 2/3 IP, 9 ER), 15 H, 3 HR, 3 BB, 14 K in 3 starts
  • Career vs. Reds: 2-3, 7.53 ERA (28 2/3 IP, 24 ER), 1.85 WHIP, 10.4 K/9 in 6 starts and 2 relief appearances

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Reds at Cubs odds

Provided by FanDuel Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 8:50 a.m. ET.

  • Moneyline (ML): Reds +116 (bet $100 to win $116) | Cubs -134 (bet $134 to win $100)
  • Run line (RL)/Against the spread (ATS): Reds +1.5 (-184) | Cubs -1.5 (+152)
  • Over/Under (O/U): 7 (O: -115 | U: -105)

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Reds at Cubs picks and predictions

Prediction

Cubs 4, Reds 2

Moneyline

BET CUBS (-134).

The Reds have lost 3 of Greene’s last 5 starts, and they have really come up short following a win, showing an inability to put streaks together. Cincinnati is 9-15 straight up following a win.

It is also the 5th-worst team as a road underdog at 7-14. The Cubs are 9-7 as a home favorite. They are strong following a loss with a 17-12 record. Considering those trends, back CUBS (-134).

Run line/Against the spread

PASS.

Greene has been playing well as of late, but the Reds have been too sporadic to back as this lofty of a run-line underdog. Similarly, the Cubs aren’t worth the risk as a run-line favorite.

Over/Under

BET UNDER 7 (-105).

The Reds started out the season as one of the hottest teams for the Over, but they have gone Under in 5 of their last 6 games. Cincinnati has scored 4 or fewer runs in 5 of its last 6 and is 26-29-2 O/U on the season.

The Reds are also 0-4-1 O/U in Greene’s last 5 starts. The Cubs are 6-6 O/U in their last 12 games and 26-30-2 O/U. With those trends in mind, back UNDER 7 (-105).

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Cincinnati Reds at Chicago Cubs odds, picks and predictions

Analyzing Friday’s Cincinnati Reds at Chicago Cubs odds and lines, with MLB expert picks, predictions and best bets.

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The Cincinnati Reds (24-32) and Chicago Cubs (28-29) kick off a 3-game series Friday at Wrigley Field. First pitch is scheduled for 2:20 p.m. ET. Let’s analyze FanDuel Sportsbook’s lines around the Reds vs. Cubs odds and make our expert MLB picks and predictions for the best bets.

Season series: First meeting; Reds won 7-6 in 2023

The Reds dropped the final 2 contests of a 3-game set against the St. Louis Cardinals Monday through Wednesday. The Under has cashed in 5 straight games for Cincinnati, while going 8-3 in the past 11 outings.

The Cubs dropped 3 of 4 games in Milwaukee Monday through Thursday, and are 1-7 in the past 8 games. They cashed the Over in each of their previous 3 outings. In fact, Chicago has allowed 47 runs across the past 8 outings, or 5.9 runs per game (RPG).

Cincinnati hits the road following a 5-4 homestand. The Reds went 3-7 in their previous road trip (May 10-19). The Under is 4-2 in their last 6 road contests.

Chicago returns home following a 1-5 road trip through St. Louis and Milwaukee. The Cubs lost their last 2 home games, both to Atlanta, and have lost 3 straight series at Wrigley Field, last winning 2 of 3 against the Milwaukee Brewers May 3-5. The Under is 6-3 in the past 9 games at the Friendly Confines.

The forecast calls for a light breeze blowing from right field to left field at an 8-11 mph clip with temperatures in the mid-60s.

Reds at Cubs projected starters

RHP Graham Ashcraft vs. RHP Javier Assad

Ashcraft (4-3, 4.67 ERA) makes his 11th start. He has a 1.44 WHIP, 3.2 BB/9 and 7.2 K/9 in 54 innings.

  • Last start: Win, 5 1/3 IP, 5 ER, 8 H, 1 HR, 1 BB, 3 K in 9-6 home victory vs. Los Angeles Dodgers May 24
  • 2024 road splits: 1-2, 2.73 ERA (33 IP, 10 ER), 1.27 WHIP, .242 opponents’ batting average (OBA), 5 HR, 11 BB, 28 K in 6 starts

Assad (4-1, 2.17 ERA) makes his 12th start. He has a 1.16 WHIP, 3.6 BB/9 and 8.4 K/9 in 58 innings.

  • Last start: Loss, 5 IP, 4 ER, 5 H, 2 HR, 3 BB, 8 K in 4-3 loss at Cardinals Sunday
  • 2024 home splits: 2-0, 1.53 ERA (27 IP, 4 ER), 1.19 WHIP, .196 OBA, 2 HR, 13 BB, 21 K in 5 starts

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Reds at Cubs odds

Provided by FanDuel Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 4:48 a.m. ET.

  • Moneyline (ML): Reds +130 (bet $100 to win $130) | Cubs -154 (bet $154 to win $100)
  • Run line (RL)/Against the spread (ATS): Reds +1.5 (-164) | Cubs -1.5 (+136)
  • Over/Under (O/U): 8 (O: -114 | U: -106)

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Reds at Cubs picks and predictions

Prediction

Cubs 4, Reds 3

Moneyline

The CUBS (-154) are a solid play as moderate favorites in the series opener at Wrigley Field, mostly due to Assad. He has been tremendous at home this season, allowing just 4 runs across 27 innings in 5 starts with a minuscule 1.33 ERA.

The Reds (+130) have been getting very good work from Ashcraft, though, especially on the road. So, be careful, and go lightly on the home side in a game which could be well pitched.

Run line/Against the spread

The Reds +1.5 (-164) are a little on the expensive side if you’re looking for some insurance and can’t bring yourself to play Cincinnati straight up.

It’s not worth it. If you like the Reds, just play their moneyline.

PASS.

Over/Under

UNDER 8 (-106) is the lean, but go with a half-unit play at best.

Ashcraft has posted solid numbers on the road, while Assad has produced good numbers at home.

While the Over cashed in Chicago’s final 3 games of the Milwaukee series, the Cubs have cashed low in the past 3 starts by Assad, while going 8-1 in his previous 9 appearances.

For the Reds, the Under has hit in 5 straight outings. As far as Ashcraft is concerned, the Over-Under has split 2-2 in the right-hander’s past 4 road assignments.

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Cincinnati Reds at Chicago Cubs odds, picks and predictions

Analyzing Thursday’s Cincinnati Reds at Chicago Cubs odds and lines, with MLB expert picks, predictions and best bets.

The Cincinnati Reds (59-51) wrap up a 4-game series against the Chicago Cubs (55-53) on Thursday at Wrigley Field. First pitch is scheduled for 8:05 p.m. ET. Let’s analyze BetMGM Sportsbook’s lines around the Reds vs. Cubs odds and make our expert MLB picks and predictions for the best bets.

Season series: Reds lead 5-3

The Reds lost 16-6 to the Cubs Wednesday despite 1B Joey Votto hitting 2 home runs. Cincinnati has been outscored 41-21 in the first 3 games of the series and 36-15 over its last 2 games but remains half a game ahead of the Milwaukee Brewers for 1st place in the NL Central.

The Cubs got home runs from DH Christopher Morel, SS Dansby Swanson, and OF Ian Happ (2), while 3B Jeimer Candelario went a perfect 4-for-4 in Wednesday’s victory. Chicago has won 10 of its last 12 games and is only 3 games back of Cincinnati in the crowded division.

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Reds at Cubs projected starters

RHP Luke Weaver vs. RHP Jameson Taillon

Weaver (2-3, 6.80 ERA) makes his 19th start. He has a 1.61 WHIP, 2.9 BB/9 and 7.0 K/9 through 86 IP.

  • Last start: Loss, 6 IP, 1 ER, 2 H, 2 BB, 2 K in 3-2 road defeat vs. Los Angeles Dodgers Saturday
  • 2023 road stats: 1-3, 5.76 ERA (50 IP, 32 ER) over 10 starts
  • Career vs. Cubs: 1-3, 8.59 ERA (29 1/3 IP, 28 ER) across 7 starts

Taillon (5-6, 5.46 ERA) makes his 19th start. He has a 1.37 WHIP, 2.8 BB/9 and 7.8 K/9 through 89 IP.

  • Last start: Win, 6 IP, 1 ER, 2 H, 4 BB, 4 K in 5-1 road win vs. St. Louis Cardinals Saturday
  • 2023 home stats: 2-4, 6.43 ERA (49 IP, 35 ER) in 10 starts
  • Career vs. Reds: 4-5, 4.64 ERA (77 2/3 IP, 40 ER) over 14 starts

Reds at Cubs odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 9 a.m. ET.

  • Moneyline (ML): Reds +135 (bet $100 to win $135) | Cubs -160 (bet $160 to win $100)
  • Run line (RL)/Against the spread (ATS): Reds +1.5 (-140) | Cubs -1.5 (+115)
  • Over/Under (O/U): 10 (O: -115 | U: -105)

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Reds at Cubs picks and predictions

Prediction

Cubs 7, Reds 5

Moneyline

After outscoring the Reds 36-15 in the last 2 games, I’ll take the CUBS (-160) at home in Thursday’s series finale. I wouldn’t wager on Chicago to win at anything steeper than -160, though.

Run line/Against the spread

CUBS -1.5 (+115) is how I’d bet on the run line with how their bats have performed in this series. Taillon has also pitched better since the All-Star break than Weaver, allowing 5 total earned runs over his last 3 starts.

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Over/Under

Even with Taillon’s recent stretch of success, OVER 10 (-115) is the play in this contest. There have been at least 11 runs scored in each game and 62 total runs scored in the first 3 games of this series.

The Over is also 9-1 in the last 10 meetings between these division rivals.

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Cincinnati Reds at Chicago Cubs odds, picks and predictions

Analyzing Wednesday’s Cincinnati Reds at Chicago Cubs odds and lines, with MLB expert picks, predictions and best bets.

The Cincinnati Reds (59-50) and Chicago Cubs (54-53) meet for the 3rd game of a 4-game series in Chicago on Wednesday. First pitch from Wrigley Field is at 8:05 p.m. ET. Let’s analyze BetMGM Sportsbook’s lines around the Reds vs. Cubs odds and make our expert MLB picks and predictions for the best bets.

Season series: Reds lead 5-2

The Reds were walloped 20-9 on Tuesday after winning the series opener 6-5 on Monday. Cincinnati is 4-4 as it continues on a 10-game road trip and has won 9 out of its last 13 games. The Reds lead the NL Central by half a game over the Milwaukee Brewers.

The Cubs snapped a 2-game losing skid with Tuesday’s outburst. They have won 9 out of their last 11 games and are in 3rd place in the NL Central, trailing Cincinnati by 4 games.

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Reds at Cubs projected starters

LHP Brandon Williamson vs. LHP Drew Smyly

Williamson (3-2, 4.48 ERA) makes his 14th start. He has a 1.34 WHIP, 3.8 BB/9 and 6.7 K/9 through 64 1/3 IP.

  • Last start: Win, 5 2/3 IP, 2 ER, 8 H, 4 BB, 2 K in 6-5 road win over Los Angeles Dodgers Friday
  • Has allowed 2 or fewer earned runs in 5 straight starts

Smyly (8-7, 4.50 ERA) makes his 20th start and 22nd appearance. He has a 1.35 WHIP, 3.1 BB/9 and 8.1 K/9 through 108 IP.

  • Last appearance: Win, 4 1/3 IP, 1 ER, 2 H, 1 BB, 6 K in relief in 3-2 road win over St. Louis Cardinals Friday
  • Was 1-2 with a 6.65 ERA across 21 2/3 IP over 3 starts and 2 relief appearances in July

Reds at Cubs odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 7:57 a.m. ET.

  • Moneyline (ML): Reds +115 (bet $100 to win $115) | Cubs -140 (bet $140 to win $100)
  • Run line (RL)/Against the spread (ATS): Reds +1.5 (-165) | Cubs -1.5 (+135)
  • Over/Under (O/U): 10 (O: -105 | U: -115)

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Reds at Cubs picks and predictions

Prediction

Reds 7, Cubs 5

Moneyline

The Reds have been good on the road this season as evidenced by their 31-24 road mark which is the 2nd-best in the NL. The Cubs are only 28-27 at home although they have won 6 of their last 8 contests at Wrigley Field.

Smyly’s 6.65 July ERA does not give great confidence in this outing, especially since Williamson has not allowed more than 2 runs in 5 straight outings.

BET REDS (+115).

Run line/Against the spread

The Reds’ 71-38 ATS mark is the best in all of baseball. They are 12-2 ATS in their last 14 games.

The Cubs are 7th at 57-50 ATS. They are 8-2 ATS in their last 10 games.

I like the Reds to win outright, so Cincinnati +1.5 (-165) isn’t nearly as good a wager as the plus-money odds on the moneyline.

PASS.

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Over/Under

Six of the 7 games in the season series have had more than 10 total runs.

Thirteen of the Cubs’ last 19 games have had at least 10 total runs.

BET OVER 10 (-105).

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Cincinnati Reds at Chicago Cubs odds, picks and predictions

Analyzing Tuesday’s Cincinnati Reds at Chicago Cubs odds and lines, with MLB expert picks, predictions and best bets.

The Cincinnati Reds (59-49) play the 2nd game of a 4-game series against the Chicago Cubs (53-53) on Tuesday at Wrigley Field. First pitch is scheduled for 8:05 p.m. ET. Let’s analyze BetMGM Sportsbook’s lines around the Reds vs. Cubs odds and make our expert MLB picks and predictions for the best bets.

Season series: Reds lead 5-1

The Reds squeaked out a 6-5 win over the Cubs in the series opener Monday as OF Will Benson connected for a double and a triple. Cincinnati is 7-3 in its last 10 games and 1 1/2 games ahead of the Milwaukee Brewers atop the NL Central.

Cubs SS Dansby Swanson hit his 13th homer of the season and C Yan Gomes supplied 3 hits in Monday’s loss. Following an 8-game win streak, Chicago has lost its last 2 games and is now 5 games back of Cincinnati in the division.

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Reds at Cubs projected starters

RHP Ben Lively vs. LHP Justin Steele

Lively (4-6, 3.76 ERA) makes his 12th start. He has a 1.21 WHIP, 2.3 BB/9 and 8.3 K/9 through 67 IP.

  • Last start: Loss, 6 2/3 IP, 2 ER, 8 H, 0 BB, 3 K in 3-0 road defeat to the Brewers Wednesday
  • Road stats: 2-4. 3.58 ERA (32 2/3 IP, 13 ER) in 5 starts and 1 relief appearance
  • Career vs. Cubs: 0-1, 10.80 ERA (5 IP, 6 ER) in 1 start on Aug. 26, 2017

Steele (11-3, 2.87 ERA) makes his 20th start. He has a 1.12 WHIP, 2.0 BB/9 and 8.2 K/9 through 109 2/3 IP.

  • Last start: Win, 6 IP, 1 ER, 5 H, 3 BB, 4 K in 10-3 road win against the St. Louis Cardinals Thursday
  • Home stats: 7-2, 2.97 ERA (60 2/3 IP, 20 ER) in 11 starts
  • Career vs. Reds: 1-3, 8.34 ERA (22 2/3 IP, 21 ER) in 5 starts and 2 relief appearances

Reds at Cubs odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 9:30 a.m. ET.

  • Moneyline (ML): Reds +135 (bet $100 to win $135) | Cubs -160 (bet $160 to win $100)
  • Run line (RL)/Against the spread (ATS): Reds +1.5 (-145) | Cubs -1.5 (+120)
  • Over/Under (O/U): 8.5 (O: -105 | U: -115)

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Reds at Cubs picks and predictions

Prediction

Cubs 5, Reds 4

Moneyline

Considering the pitchers that are taking the mound on Tuesday, I’ll side with the CUBS (-160) and Steele at home. Steele has struggled against the Reds in his career, but he’s been one of the best pitchers in baseball this season.

Run line/Against the spread

REDS +1.5 (-145) is the choice for the spread as Cincinnati should keep this game close. Steele has shown he’s susceptible to giving up runs in recent starts and Cincinnati has won 5 of the first 6 meetings between these clubs this season.

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Over/Under

OVER 8.5 (-105) is how I’d bet on the run total in this divisional showdown even with Steele having a strong campaign. The Over is 8-2 in the last 10 meetings overall.

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Cincinnati Reds at Chicago Cubs odds, picks and predictions

Analyzing Monday’s Cincinnati Reds at Chicago Cubs odds and lines, with MLB expert picks, predictions and best bets.

The Cincinnati Reds (58-49) and Chicago Cubs (53-52) play the opener of a 4-game set at Wrigley Field Monday. First pitch is at 8:05 p.m. ET. Let’s analyze BetMGM Sportsbook’s lines around the Reds vs. Cubs odds and make our expert MLB picks and predictions for the best bets.

Season series: Reds lead 4-1

The Reds took 2 of 3 from the Los Angeles Dodgers over the weekend, capped off by a 9-0 shutout Sunday. They’re 7-3 over the last 10 games and have taken a half-game lead on the Milwaukee Brewers in the NL Central. The Reds have been better on the road at 30-23 as opposed to 28-26 at home. They have had trouble within the division, though, at 13-19.

The Cubs had an 8-game winning streak snapped with a 3-0 loss to the St. Louis Cardinals Sunday. The Cubs sit 4 games out in the division and 3 1/2 out of a Wild-Card spot. They announced they weren’t selling over the weekend and could add to their pitching staff over the next couple of days. They’re 18-13 within the division.

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Reds at Cubs projected starters

LHP Andrew Abbott vs. RHP Marcus Stroman

Abbott (6-2, 1.90 ERA) makes his 11th start. He has a 0.96 WHIP, 2.8 BB/9 and 9.6 K/9 in 61 2/3 innings.

  • Last start: Win, 6 IP, 0 ER, 7 H, 1 BB, 9 K Tuesday in 4-3 win over the Milwaukee Brewers
  • Has not faced Cubs
  • Home/road splits: 4-1, 2.25 ERA, 1.32 WHIP, 9.3 K/9 in 5 road starts; 2-1, 1.60 ERA, 0.65 WHIP, 9.9 K/9 in 5 home starts

Stroman (10-7, 3.51 ERA) makes his 23rd start. He has a 1.20 WHIP, 3.4 BB/9 and 7.8 K/9 in 125 2/3 innings.

  • Last start: No-decision, 3 1/3 IP, 7 ER, 9 H, 2 BB, 4 K in Wednesday 10-7 win against the Chicago White Sox
  • Last 5 starts vs. Reds: 3-1, 2.45 ERA, 1.02 WHIP, 28 K in 29 1/3 IP

Reds at Cubs odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 8:40 a.m. ET.

  • Moneyline (ML): Reds +100 (bet $100 to win $100) | Cubs -120 (bet $120 to win $100)
  • Run line (RL)/Against the spread (ATS): Reds +1.5 (-200) | Cubs -1.5 (+165)
  • Over/Under (O/U): 8 (O: -110 | U: -110)

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Reds at Cubs picks and predictions

Prediction

Reds 6, Cubs 5

Moneyline

The Cubs’ winning streak was impressive, but they did it against the Cardinals and White Sox. The Reds have played 4 straight teams in the playoff mix and won 7 of 10. They’ve also taken it to the Cubs this year with 3 of their 4 wins by 3 runs or more. Cincinnati won all 3 at Wrigley this year.

I’ll take the REDS +100.

Run line/Against the spread

The Cubs are favored in this game, and I’m not keen enough on Cincinnati’s bullpen to take the multi-run win. I’ll PASS and stick to the ML.

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Over/Under

The Reds are just 2-8 O/U over the last 10, and the Cubs are 4-4-2. All 5 games have gone Over between the teams this year as each game went north of 10. Stroman has an 8.00 ERA over his last 6 starts, and we have seen 6 straight Overs cash in this matchup. I think we’ll see 7.

Take the OVER 8 (-110).

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Cincinnati Reds at Chicago Cubs odds, picks and predictions

Analyzing Saturday’s Cincinnati Reds at Chicago Cubs odds and lines, with MLB expert picks, predictions and best bets.

The Chicago Cubs (22-28) welcome the Cincinnati Reds (22-29) to Wrigley Field Saturday. First pitch is set for 7:15 p.m. ET (FOX). Let’s analyze BetMGM Sportsbook’s lines around the Reds vs. Cubs odds and make our expert MLB picks and predictions for the best bets.

Season series: Reds lead 2-1.

The Reds are coming off a 9-0 win to open the series and have alternated winning and losing over their last 6 games. They are 8-15 on the road.

Chicago, on the other hand, is 13-13 at home yet just 3-7 over its last 10. The Cubs ranked 4th in the MLB in on-base percentage (.335).

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Reds at Cubs projected starters

LHP Brandon Williamson vs. RHP Jameson Taillon

Williamson (0-0, 3.60 ERA) makes his 3rd start. He has a 1.20 WHIP, 5.4 BB/9 and 8.1 K/9 through 10 IP.

  • This will be Williamson’s 3rd career start. He was traded by Seattle in the 2022 blockbuster deal for Jesse Winker and Eugenio Suarez.
  • The Reds are 2-0 with him as the starter.

Taillon (0-3, 8.10 ERA) makes his 8th start. He has a 1.73 WHIP, 3.4 BB/9 and 9.1 K/9 through 26 2/3 IP.

  • Taillon has had a win percentage greater than .500 in each season he’s topped 7 starts. He was 14-5 last season with the Yankees.
  • The Cubs are 0-7 with Taillon as the starter, and he has gone more than 3 innings in just 1 of his last 4 games.

Reds at Cubs odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 10:15 a.m. ET.

  • Moneyline (ML): Reds +145 (bet $100 to win $145) | Cubs -175 (bet $175 to win $100)
  • Run line (RL)/Against the spread (ATS): Reds +1.5 (-135) | Cubs -1.5 (+110)
  • Over/Under (O/U): 8.5 (O: -115 | U: -105)

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Reds at Cubs picks and predictions

Prediction

Cubs 6, Reds 5

Moneyline

PASS.

The Cubs haven’t performed too well at home, and with a (-175) tag on them to win straight up, Chicago is too expensive to bet to win.

Cincinnati, at the same time, might be an underdog but is just 8-15 away from home and has been extremely inconsistent this season. Avoid the moneyline option.

Run line/Against the spread

LEAN REDS +1.5 (-135).

The Reds are 29-22 against the spread (ATS) this season, and they have covered 4 of their last 5 games. Cincinnati is 3-3 ATS on the road over its last 6 and 13-10 ATS on the road this season.

Chicago is 9-9 ATS as a home favorite. While he has been solid throughout his career, the lack of performance from Taillon is also concerning and should allow the Reds’ bats to heat up.

Take the REDS +1.5 (-135).

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Over/Under

BET OVER 8.5 (-115).

If there’s one thing both teams have done well, it is cover the Over. Chicago is 26-23-1 O/U and has gone Over in its last 2 games. It is 12-2-1 O/U in its last 15.

The Reds are 28-23 O/U this season and 4-1 O/U in their last 5 games. They are 14-7 O/U following a win as well. Back the OVER 8.5 (-115).

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Cincinnati Reds at Chicago Cubs odds, picks and predictions

Analyzing Thursday’s Cincinnati Reds at Chicago Cubs odds and lines, with MLB expert picks and predictions.

The Cincinnati Reds (54-80) and Chicago Cubs (57-79) have split the first 2 games of their series and will settle things on Thursday at 2:20 p.m. ET at Wrigley Field. Let’s analyze Tipico Sportsbook‘s lines around the Reds vs. Cubs odds with MLB picks and predictions.

Season series: Cubs lead 7-5

The Reds have alternated wins and losses in their last 8 games. After they were perhaps the worst team in the league for half a season, they are now 26-26 in their last 52 contests.

The Cubs have been scuffling lately and Wednesday’s loss was their 8th in their last 10 games.

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Reds at Cubs projected starters

RHP Luis Cessa vs. RHP Adrian Sampson

Cessa (3-2, 5.18 ERA) makes his 41st appearance (5th start). He has a 1.42 WHIP, 3.3 BB/9 and 6.7 K/9 in 48 2/3 IP.

  • After being mostly ineffective in a relief role, the Reds are stretching him out as a starter; his 69 pitches and 5 IP last time out were season-highs
  • He has been HR-prone throughout the season (1.8 HR/9) and has allowed 4 homers in just 12 IP as a starter.

Sampson (1-5, 3.95 ERA) makes his 16th appearance and 14th start. He has a 1.33 WHIP, 2.4 BB/9 and 6.9 K/9 in 70 2/3 IP.

  • Prior to this season he was sporting an unsightly 2.2 HR/9 in 188 1/3 career IP, but has held HRs in check in 2022 with a 0.9 HR/9
  • The sample is pretty small, but Sampson hasn’t been all that effective at home. In 38 IP at Wrigley Field, he has allowed 6 HR while registering a 4.50 ERA and 4.7 K/9.

Reds at Cubs odds

Provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 9:21 a.m. ET.

  • Money line (ML): Reds +120 (bet $100 to win $120) | Cubs -145 (bet $145 to win $100)
  • Run line (RL)/Against the spread (ATS): Reds +1.5 (-175) | Cubs -1.5 (+140)
  • Over/Under (O/U): 8.5 (O: +100 | U: -125)

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Reds at Cubs picks and predictions

Prediction

Cubs 6, Reds 4

Money line

Cessa hasn’t been good at all in short stints this season and can’t be expected to find much success as a starter. He isn’t likely to work very deep into the game either, regardless of how he’s pitching, and he’ll turn things over to a bullpen with a league-worst 4.78 ERA. Back the CUBS -145.

Run line/Against the spread

While Sampson hasn’t been great at home, he has had a pretty solid season overall and gets a Cincinnati team averaging 3.56 runs per game on the road, tied for 26th in the league. He should get a fair amount of run support today and his team could roll in this one. Take the CUBS -1.5 (+140).

Over/Under

The Cub offense looks set for a pretty good day against Cessa and a weak Cincinnati bullpen. The Reds aren’t likely to get completely shut down by Sampson, either. Lock in OVER 8.5 (+100), which should hit with room to spare.

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