Pittsburgh Steelers at Buffalo Bills odds, picks and predictions

Analyzing Sunday’s Pittsburgh Steelers at Buffalo Bills odds and lines, with expert NFL picks, predictions and best bets.

The Pittsburgh Steelers (1-3) and Buffalo Bills (3-1) meet Sunday at Highmark Stadium. Kickoff is set for 1 p.m. ET (CBS). Below, we analyze Tipico Sportsbook‘s lines around the Steelers vs. Bills odds, and make our expert NFL picks and predictions.

Steelers rookie QB Kenny Pickett played in his 1st NFL game in a 24-20 loss to the New York Jets last Sunday. Pickett threw for 120 yards and 3 INTs on 10-of-13 passing as Pittsburgh failed to cover as a 3-point favorite.

Pittsburgh is 1-3-1 against the spread (ATS) in its last 5 games.

Bills K Tyler Bass made a game-winning 21-yard FG in a 23-20 win at the Baltimore Ravens last Sunday. QB Josh Allen finished with 213 yards, 1 passing TD and 1 INT and ran for a score.

Buffalo is 9-1-2 ATS vs. teams with a losing record.

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Steelers at Bills odds

Provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 12:01 a.m. ET.

  • Moneyline (ML): Steelers +650 (bet $100 to win $650) | Bills -1000 (bet $1,000 to win $100)
  • Against the spread (ATS): Steelers +13.5 (-103) | Bills -13.5 (-117)
  • Over/Under (O/U): 45.5 (O: -108 | U: -112)

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Steelers at Bills injuries

Steelers

  • S Terrell Edmunds (concussion) out
  • CB Cameron Sutton (hamstring) questionable
  • CB Ahkello Witherspoon (hamstring) out

Bills

  • CB Christian Benford (hand) out
  • WR Jamison Crowder (ankle) out
  • OL Tommy Doyle (knee) out
  • LB Tremaine Edmunds (hamstring) questionable
  • Micah Hyde (neck) out
  • TE Dawson Knox (foot) out
  • WR Jake Kumerow (ankle) out
  • WR Isaiah McKenzie (concussion) questionable
  • DL Ed Oliver (ankle) questionable
  • DL Jordan Phillips (hamstring) questionable
  • Jordan Poyer (undisclosed) out
  • CB Tre’Davious White (knee) out

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Steelers at Bills picks and predictions

Prediction

Bills 31, Steelers 10

Moneyline

PASS.

Bills (-1000) will hit, but the price is too high. The spread and the total provide better opportunities.

Against the spread

Bet BILLS -13.5 (-117).

Pittsburgh coach Mike Tomlin has never been this big of an underdog ATS. This is not an opportunity for Steelers bettors, as the Bills have a Mike Tyson knockout quality. Expect Buffalo to win by margin vs. a vulnerable Pittsburgh team.

Over/Under

Bet UNDER 45.5 (-112).

The Under is 6-1 in their last 7 meetings and 3-1 in Buffalo’s last 4 games. Pittsburgh should struggle to score Sunday in Pickett’s first start and help the Under hit.

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Pittsburgh Steelers at Buffalo Bills odds, picks and prediction

Analyzing the Pittsburgh Steelers at Buffalo Bills Week 1 odds and lines, with expert NFL picks, predictions and best bets.

Once again led by QB Ben Roethlisberger, the Pittsburgh Steelers will open the season on the road against the Buffalo Bills, who are projected to be one of the best teams in the AFC. Kickoff is set for 1 p.m. ET Sunday at Highmark Stadium. Below, we look at the Steelers vs. Bills odds and lines, and make our best NFL picks, predictions and bets.

After starting last season 11-0, the Steelers lost five of their last six games, including a postseason loss to the Cleveland Browns in the wild-card round. Now with RB Najee Harris in the backfield and WR JuJu Smith-Schuster back on a one-year deal, Pittsburgh has the playmakers to once again reach the playoffs this season.

QB Josh Allen is the catalyst that makes the Bills go and he’ll look to follow up a career year in 2020 with a potential MVP season this year. WR Stefon Diggs remains the top wideout, while RBs Zack Moss and Devin Singletary will split time in the backfield. The defense will look to improve, too, after finishing 16th in scoring last year.

Also see: NFL team win totals

Steelers at Bills odds, spread and lines

Odds provided by Tipico Sportsbook; access USA TODAY Sports’ betting odds for a full list. Lines last updated Friday at 5:15 p.m. ET.

  • Money line: Steelers +220 (bet $100 to win $220) | Bills -280 (bet $280 to win $100)
  • Against the spread (ATS): Steelers +6.5 (-110) | Bills -6.5 (-110)
  • Over/Under (O/U): 47.5 (O: -115 | U: -105)

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Steelers at Bills key injuries

Steelers

  • LB Alex Hightower (groin) questionable

Bills

  • DT Star Lotulelei (calf) out
  • WR Emmanuel Sanders (foot) questionable

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Steelers at Bills odds, lines, predictions and picks

Prediction

Bills 27, Steelers 17

Money line

The Steelers have the edge on defense, but this game will come down to quarterback play and Buffalo has a huge advantage in that department. Allen will do enough to help the Bills win this game despite a decent effort from Pittsburgh’s defense.

The Steelers don’t look any better now than they did at the end of last season and Roethlisberger is another year older. Give me the BILLS (-280) with a small wager on the money line.

Against the spread

The Bills covered the spread nine times across their last 11 games last season. The Steelers, on the other hand, covered only twice in their last seven games. The 6.5-point spread is larger than most games in Week 1, but the Bills are one of the best teams in football on paper.

Take the BILLS -6.5 (-110) to cover and win by at least a touchdown.

Over/Under

The Bills won last season’s head-to-head meeting 26-15. The Pittsburgh defense should have one of the best pass rushes in the game once again, led by OLB T.J. Watt, which could give the Bills some trouble.

On the other side, I expect the Bills secondary to pick off a couple of passes to limit Pittsburgh’s offense. Bet the UNDER 47.5 (-105).

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Pittsburgh Steelers at Buffalo Bills odds, picks and prediction

Previewing the Pittsburgh Steelers at Buffalo Bills Week 14 betting odds and lines, with NFL betting picks, tips and predictions.

The Pittsburgh Steelers (11-1) visit the Buffalo Bills (9-3) for the Week 14 Sunday Night Football game at 8:20 p.m. ET. Below, we preview the Steelers-Bills betting odds and lines and make our NFL picks and predictions.

Steelers at Bills: Betting odds, spread and lines

Odds via BetMGM; access USA TODAY Sports’ betting odds for a full list. Lines last updated at 1:20 a.m. ET.

  • Money line: Steelers +115 (bet $100 to win $115) | Bills -135 (bet $135 to win $100)
  • Against the spread/ATS: Steelers +1.5 (-110) | Bills -1.5 (-110)
  • Over/Under: 48.5 (O: -115 | U: -105)

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Steelers at Bills: Game notes

  • The Steelers are coming off their first loss of the season, suffering a surprising 23-17 upset at home by the Washington Football Team Monday in Week 13. Pittsburgh, which was a 6-point favorite, led 14-3 at the half and 17-10 early in the fourth quarter before, but Washington rallied and kicked the go-ahead field goal with 2:07 left. The Steelers really struggled on the ground, finishing with just 21 rushing yards on 14 carries.
  • The Bills, who lead the Miami Dolphins (8-4) by one game atop the AFC East, have won two in a row and five of six. In Week 13, QB Josh Allen threw for 375 yards and a career-tying four TDs in an impressive 34-24 victory vs. the San Francisco 49ers in the Monday Night Football game. The 49ers were the home team – and 1.5-point favorites – but the game was played in Glendale, Ariz., due to COVID-19 protocol rules in Santa Clara County, Calif.
  • With its first loss, Pittsburgh now has the same record as the Kansas City Chiefs. The Steelers, however, hold the tiebreaker for the AFC’s No. 1 seed because of a better win percentage in conference games (with 4 weeks to go).
  • Pittsburgh holds a two-game lead over the Cleveland Browns (9-3) in the AFC North. The two will meet in Cleveland in their regular-season finale in Week 17.
  • The Bills went into Pittsburgh last season and claimed a 17-10 victory in Week 15 as 1-point dogs. It was a memorable trip for the Bills as it was their 10th win of the season and they clinched a playoff berth. They outscored the Steelers 10-0 in the final quarter and Allen finished with a passing touchdown and a rushing touchdown.
  • The Steelers are 10-2 in their last 12 vs. the Bills, and they had won 6 straight in the series before last year’s loss.

Betting stats:

  • ATS: Steelers 8-4 | Bills 7-5
  • O/U: Steelers 4-6-2 | Bills 8-3-1

Steelers at Bills: Key injuries

Steelers

  • CB Joe Haden (concussion) out
  • LB Robert Spillane (knee) out
  • LB Vince Williams (COVID-19) out

Steelers at Bills: Odds, betting lines, predictions and picks

Prediction

Bills 34, Steelers 23

Money line (?)

The Bills (-135) have definitely been playing better than the Steelers (+115) as of late, and I’m calling for a Buffalo win here. However, instead of laying the -135 juice, I’ll lay the points with the spread below. PASS.

Against the spread (?)

BUFFALO -1.5 (-110) is the STRONGEST PLAY – 1½ times your usual wager. The home team will take care of business against a Steelers squad that is struggling.

Over/Under (?)

Back the OVER 45.5 (-115). Both teams have averaged 27.8 points per game this season. While Pittsburgh has to figure some offensive issues out, Buffalo has averaged 33.8 PPG in its last four games. The Over should hit early in the fourth quarter if not sooner.

Want action on this NFL game? Sign up and bet at BetMGM. If you’re looking for more sports betting picks and tips, visit SportsbookWire.com. Please gamble responsibly.

Also see:

Johnny’s 2020 NFL record / Strongest plays 19-16-1 / 7-7-1
2019 NFL record / Strongest plays 17-10-1 / 7-4
2020 overall record (all sports) 160-120-3
Strongest plays (all sports) 78-47-1

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