New England Patriots at Carolina Panthers odds, picks and prediction

Analyzing Sunday’s New England Patriots at Carolina Panthers odds and lines, with expert NFL picks, predictions and best bets.

Winners of two straight, the New England Patriots (4-4) are on the road against the Carolina Panthers (4-4). They face one another Sunday at 1 p.m. ET at Bank of America Stadium. Below, we look at the Patriots vs. Panthers odds and lines, and make our best NFL picks, predictions and bets.

The New England defense picked off QB Justin Herbert twice, with S Adrian Phillips returning one for a touchdown, while K Nick Folk make four field goals in a 27-24 win over the Los Angeles Chargers. Rookie QB Mac Jones has not turned the ball over the last two games.

The Panthers snapped a four-game losing streak last week with a 19-13 win over the Atlanta Falcons. The defense held Atlanta to 213 yards of offense and picked off QB Matt Ryan twice in the win.

Patriots at Panthers odds, spread and lines

Odds provided by Tipico Sportsbook; access USA TODAY Sports’ betting odds for a full list. Lines last updated Saturday at 11:25 p.m. ET.

  • Money line: Patriots -190 (bet $190 to win $100) | Panthers +155 (bet $100 to win $155)
  • Against the spread (ATS): Patriots -3.5 (-105) | Panthers +3.5 (-115)
  • Over/Under (O/U): 41.5 (O: -105 | U: -115)

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Patriots at Panthers key injuries

Patriots

  • Nick Folk (knee) questionable
  • WR N’Keal Harry (knee) questionable
  • LB Dont’a Hightower (ankle) questionable
  • Shaq Mason (abdomen) questionable
  • TE Jonnu Smith (shoulder) questionable

Panthers

  • QB Sam Darnold (concussion, shoulder) questionable
  • Pat Elflein (hamstring) questionable

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Patriots at Panthers odds, lines, predictions and picks

Prediction

Patriots 21, Panthers 17

Money line

The Patriots are 3-0 on the road this season. Jones is taking care of the football, while the Panthers have been in a tailspin.

QB Sam Darnold has not had a passing touchdown in his last two games. The Panthers are No. 2 in total defense and allow the fifth-fewest points in the league.

But Jones will continue to be effective and to protect the football.

Take the Patriots (-190).

Against the spread

Both teams are 4-4 ATS this season, but the Pats have covered the spread in their last two games, while the Panthers, before their win over the Falcons last week, had failed to cover the spread in four straight games.

The Pats are 2-3 ATS as a favorite.

I expect this to be close and come down to the wire.

Take the PATRIOTS -3.5 (-105).

Over/Under

The Patriots have had each of their last four games hit the Over.

Only two of the Panthers’ games this season have not gone Under the projected total.

This will be a defensive battle between two top-10 defensive teams.

Take UNDER 41.5 (-115).

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