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The New England Patriots (1-2) will travel South to face the Dallas Cowboys (2-1) in Week 4 Sunday at AT&T Stadium. Kickoff is scheduled for 4:25 p.m. ET (FOX). Below, we analyze BetMGM Sportsbook’s lines around the Patriots vs. Cowboys odds, and make our expert NFL picks and predictions.
The Patriots covered the 2.5-point spread as road favorites in their 15-10 victory against the New York Jets in Week 3. The Under of 35.5 also hit in a game where QB Mac Jones and QB Zach Wilson combined for only 358 passing yards.
It was a surprising loss for the Cowboys in Week 3, failing to cover as 11-point road favorites in their 28-16 loss to the Arizona Cardinals. The Over of 43.5 cleared with the Cardinals doing most of the heavy lifting themselves.
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Patriots at Cowboys odds
Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Saturday at 11:40 a.m. ET.
- Moneyline (ML): Patriots +225 (bet $100 to win $225) | Cowboys -275 (bet $275 to win $100)
- Against the spread (ATS): Patriots +6.5 (-115) | Cowboys -6.5 (-105)
- Over/Under (O/U): 43.5 (O: -110 | U: -110)
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Patriots at Cowboys key injuries
Patriots
- DT Christian Barmore (knee) questionable
- DT Davon Godchaux (ankle) questionable
- CB Jonathan Jones (ankle) questionable
- G Cole Strange (knee) questionable
Cowboys
- C Tyler Biadasz (hamstring) questionable
- G Zach Martin (ankle) questionable
- OT Tyron Smith (knee) questionable
Patriots at Cowboys picks and predictions
Prediction
Cowboys 24, Patriots 20
Moneyline
Vegas seems to believe the Cowboys are in a perfect bounce-back spot at home against the Patriots in Week 4. Despite that being the case, I’ll PASS on the moneyline in this game for either team.
Against the spread
With the Patriots now having a watchable offense under new offensive coordinator Bill O’Brien, taking the PATRIOTS +6.5 (-115) to cover the spread is a wise choice. New England played the Miami Dolphins and the Philadelphia Eagles competitively before beating New York in Week 3.
In the 5 meetings the Patriots and Cowboys have had since 2007, New England has either won or kept the game within 7 points. That includes a 35-29 overtime loss to the Cowboys in 2021.
Over/Under
LEAN OVER 43.5 (-110).
While the Cowboys are dealing with injuries along their offensive line, the Patriots are banged up in the interior of their defensive line. After losing to the Cardinals, RB Tony Pollard will be even more involved on the ground and should have more success.
Meanwhile, the loss of CB Trevon Diggs for the season hurts the Cowboys tremendously, allowing the Patriots to sustain more drives through the air. We saw Arizona put up 28 points on Dallas’ defense and the Cowboys are 2-1 to the Over to begin the season.
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