First look: Carolina Panthers at Los Angeles Rams odds and lines

Looking at Sunday’s Carolina Panthers at Los Angeles Rams Week 6 NFL odds, lines and trends. Here’s what you need to know.

The Carolina Panthers (1-4) and Los Angeles Rams (2-3) square off Sunday. Kickoff from SoFi Stadium will be at 4:05 p.m. ET (FOX). Below, we look at Panthers vs. Rams odds from Tipico Sportsbook; check back for all our NFL picks and predictions.

The Panthers were demolished 37-15 at home by the San Francisco 49ers in Week 5 and now sit last in the NFC South. QB Baker Mayfield has statistically been one of the worst passers in the NFL this season, only topping 200 yards twice and throwing 4 touchdowns with 4 interceptions. Carolina fired coach Matt Rhule Monday; he will be replaced on an interim basis by Steve Wilks.

Also seeAll Week 6 odds and lines

The Rams were embarrassed for the second week in a row in Week 5 as they fell 22-10 at home to the Dallas Cowboys. Los Angeles has scored just 1 touchdown in the last 2 weeks, struggling to get anything going offensively. The defense held Dallas to just 1 offensive touchdown, but it still wasn’t enough to earn the win.

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Panthers at Rams odds

Provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Monday at 1:20 p.m. ET.

  • Moneyline (ML): Panthers +380 (bet $100 to win $380) | Rams -500 (bet $500 to win $100)
  • Against the spread (ATS): Panthers +9.5 (-101) | Rams -9.5 (-120)
  • Over/Under (O/U): 41.5 (O: -105 | U: -115)

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2022 betting stats

  • ML: Panthers 1-4 | Rams 2-3
  • ATS: Panthers 1-4 | Rams 1-4
  • O/U: Panthers 2-3 | Rams 1-4

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Panthers vs. Rams head-to-head

The Rams and Panthers have only played once since 2017 when Sean McVay became Los Angeles’ coach. That meeting came in the 2019 season opener, which the Rams won 30-27 on the road.

The Panthers are 6-2 in their last 8 games against the Rams and lead the all-time series, 13-9. Carolina is 3-2-1 ATS across the last 6 meetings and the total has gone Under 4 times along that span.

This will be the largest spread in the last 6 Rams-Panthers games, with the previous high being Panthers -7.5 in 2013.

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