Baltimore Orioles at Boston Red Sox odds, picks and predictions

Analyzing Wednesday’s Baltimore Orioles at Boston Red Sox odds and lines, with MLB expert picks, predictions and best bets.

The Baltimore Orioles (83-63) and the Boston Red Sox (73-72) meet Wednesday to finish their 3-game series. First pitch from Fenway Park is scheduled for 7:10 p.m. ET. Let’s analyze BetMGM Sportsbook’s lines around the Orioles vs. Red Sox odds and make our expert MLB picks and predictions for the best bets.

Season series: Baltimore leads 8-4

After their 12-3 loss in the 1st game, Baltimore responded by winning Game 2. Before the 4th inning, Orioles CF Cedric Mullins hit 2 HRs for a 3-0 lead. The Red Sox cut the lead behind DH Masataka Yoshida‘s RBI double and an Orioles balk, but Baltimore held on for a 5-3 win as the (+120) road underdog. The Under (9.5) also hit.

Orioles at Red Sox projected starters

RHP Dean Kremer vs. RHP Nick Pivetta

Kremer (7-9, 4.27 ERA) makes his 22nd start. He has a 1.27 WHIP, 3.8 BB/9 and 8.5 K/9 in 111 2/3 IP.

  • Last start: Win, 6 IP, 0 ER, 2 H, 3 BB, 7 K in 2-0 home win against Tampa Bay Rays Friday
  • 2024 road stats: 4-5, 4.26 ERA (57 IP, 27 ER), 1.15 WHIP, 8.7 K/9 in 11 starts
  • Career versus Red Sox: 2-4, 6.45 ERA (37 2/3, 27 ER), 1.54 WHIP, 7.9 K/9 in 8 starts

Pivetta (5-10, 4.38 ERA) makes his 23rd start and 24th appearance. He has a 1.15 WHIP, 2.3 BB/9 and 10.7 K/9 in 123 1/3 IP.

  • Last start: No decision, 6 IP, 1 ER, 5 H, 3 BB, 6 K in 3-1 home win against Chicago White Sox Friday
  • 2024 home stats: 2-5, 4.61 ERA (54 2/3 IP, 28 ER), 1.22 WHIP, 12.0 K/9 in 9 starts and 1 appearance
  • Career versus Orioles: 8-3, 3.33 ERA (73 IP, 27 ER), 1.08 WHIP, 11 K/9 in 21 appearances (17 starts).

Who’s going yard? Here’s a breakdown of today’s best home run props with our top picks. Include the BetMGM bonus code SBWIRE to score a $1,500 first-bet offer.

Orioles at Red Sox odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 9:41 a.m. ET.

  • Moneyline (ML): Orioles +120 (bet $100 to win $120) | Red Sox -140 (bet $140 to win $100)
  • Run line (RL)/Against the spread (ATS): Orioles -1.5 (+185) | Red Sox +1.5 (+150)
  • Over/Under (O/U): 9.5 (O: +100 | U: -120)

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Orioles at Red Sox picks and predictions

Prediction

Orioles 4, Red Sox 2

Moneyline

The Red Sox post the 3rd-worst record (24-32) as a home favorite, lower than the Washington Nationals, Chicago White Sox and Colorado Rockies.

I like tailing that trend, especially with the Orioles currently at plus money and their pitcher with better splits on the road versus at home.

BET ORIOLES (+120).

Run line/Against the spread

Baltimore has the 3rd-best cover rate (46-36) coming off a win. Plus they are 32-16 ATS against the AL East, while Boston is 16-22. Overall the Orioles have the 3rd-best ATS record (80-66), behind 2 teams (Cincinnati Reds and Washington Nationals) with losing records and are often taking points.

Since I already like Baltimore straight up, I would only put half a unit on them to cover too.

LEAN ORIOLES -1.5 (+185).

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Over/Under

As a home favorite, Boston has an Under record of 30-23-3 (56.6%). In their last 8 road games, Baltimore is 4-4 on O/U while Boston is 6-2 toward the Under in their last 8 games at home.

LEAN UNDER 9.5 (-120).

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Baltimore Orioles at Boston Red Sox odds, picks and predictions

Analyzing Tuesday’s Baltimore Orioles at Boston Red Sox odds and lines, with MLB expert picks, predictions and best bets.

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The Baltimore Orioles (82-63) and Boston Red Sox (73-71) play the 2nd game of a 3-game series Tuesday. First pitch from Fenway Park is set for 7:10 p.m. ET. Let’s analyze FanDuel Sportsbook’s lines around the Orioles vs. Red Sox odds and make our expert MLB picks and predictions for the best bets.

Season series: Orioles lead 7-4

The Orioles dropped their third straight game Monday, losing 12-3 to the Red Sox. SP Cade Povich and RP Burch Smith both struggled, allowing a combined 8 earned runs on 9 hits. The only bright spot for Baltimore was RF Anthony Santander hitting his 40th home run of the season. With the loss, the 2nd-place Orioles find themselves 1½ games behind the AL East-leading New York Yankees.

The Red Sox improved to 3-1 on their current 6-game homestand with Monday’s win. RF Rob Refsnyder had an unforgettable performance, going 4 for 4 with 2 homers, a double, and 5 RBIs. DH Tyler O’Neill matched his power, going 3 for 5 with 2 HRs while CF Ceddanne Rafaela added 4 RBIs to cap off a dominant night for Boston.

Orioles at Red Sox projected starters

RHP Albert Suarez vs. RHP Kutter Crawford

Suarez (7-5, 3.49 ERA) makes his 21st start and 26th appearance. He has a 1.31 WHIP, 2.9 BB/9 and 6.9 K/9 in 113 1/3 IP.

  • Last start: Loss, 4 1/3 IP, 6 ER, 8 H, 2 BB, 2 K in 8-1 home defeat against Chicago White Sox Wednesday
  • 2024 away splits: 4-3, 3.75 ERA (57 2/3 IP, 24 ER), 1.37 WHIP, 7.2 K/9 in 15 appearances (10 starts)
  • Last start vs Red Sox: Win, 6 IP, 0 ER, 7 H, 0 BB, 6 K in 4-2 home victory Aug. 18

Crawford (8-13, 4.08 ERA) makes his 30th start. He has a 1.08 WHIP, 2.5 BB/9 and 8.3 K/9 in 161 IP.

  • Last start: Loss, 6 IP, 2 ER, 1 H, 2 BB, 8 K in 7-2 road setback against New York Mets Sept. 3
  • 2024 home splits: 4-7, 4.06 ERA (82 IP, 37 ER), 1.10 WHIP, 8.2 K/9 in 15 starts
  • 2024 vs Orioles: 0-2, 4.41 ERA (16 1/3 IP, 8 ER), 0.93 WHIP, 8.4 K/9 in 3 starts

Who’s going yard? Here’s a breakdown of today’s best home run props with our top picks. Include the BetMGM bonus code SBWIRE to score a $1,500 first-bet offer.

Orioles at Red Sox odds

Provided by FanDuel Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated 11:52 p.m. ET.

  • Moneyline (ML): Orioles -108 (bet $108 to win $100) | Red Sox -108 (bet $108 to win $100)
  • Run line (RL)/Against the spread: Orioles -1.5 (+138) | Red Sox +1.5 (-166)
  • Over/Under (O/U): 9.5 (O: -104 | U: -118)

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Orioles at Red Sox picks and predictions

Prediction

Orioles 5, Red Sox 3

Moneyline

BET ORIOLES (-108).

The Orioles need a win Tuesday, now 1½ games back of the Yankees in the AL East after Monday’s loss. They’ve done well against the Red Sox this season, taking 7 of the 11 meetings and outscoring Boston 66-54. Even though Baltimore’s hit a rough patch, losing 4 of its last 5, it has still been solid on the road with a 40-30 record.

The Red Sox haven’t been much better lately, dropping 6 of their last 9. With Crawford struggling against the Orioles and Suarez having already shut them down once, Baltimore’s got a good shot to get back on track.

Run line/Against the spread

PASS.

I don’t love the odds, so I’ll keep my focus on the moneyline and total.

Over/Under

BET UNDER 9.5 (-118).

The Under has hit in 3 of the last 5 meetings, including the same pitching matchup Aug. 18.

Suarez has been particularly strong in this department, with the Under hitting in 5 of his last 6 starts. Crawford’s also been reliable for Under bettors, with the total going Under in 3 of his last 4 starts. Given these trends and recent performances, betting the Under looks like a smart move.

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Baltimore Orioles at Boston Red Sox odds, picks and predictions

Analyzing Monday’s Baltimore Orioles at Boston Red Sox odds and lines, with MLB expert picks, predictions and best bets.

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The Baltimore Orioles (82-62) and Boston Red Sox (72-71) begin a 3-game series Monday. First pitch from Fenway Park is set for 7:10 p.m. ET. Let’s analyze FanDuel Sportsbook’s lines around the Orioles vs. Red Sox odds and make our expert MLB picks and predictions for the best bets.

Season series: Orioles lead 7-3

The Orioles lost 2-0 to the Tampa Bay Rays on Sunday, despite a strong performance from RHP Corbin Burnes, who allowed just 2 runs (LF Jonny DeLuca’s 6th-inning HR) in 6 IP. The Orioles’ offense faltered, going 0-for-7 with runners in scoring position and leaving 9 men on base. Baltimore is 2nd in the AL East, a half-game behind the New York Yankees and 9 1/2 games up on 3rd-place Boston.

The Red Sox lost 7-2 to the Chicago White Sox on Sunday, giving up 5 runs in the 9th inning. Despite solo HRs from RF Wilyer Abreu and C Connor Wong, Boston’s offense was flat. RHP Richard Fitts had a solid MLB debut (5 2/3 IP, 2 R 0 ER, 6 H, 1 BB, 2 K), but the bullpen couldn’t stop Chicago’s late surge. Boston is 4 games out of the last Wild Card spot.

Orioles at Red Sox projected starters

RHP Albert Suarez vs. RHP Kutter Crawford

Suarez (7-5, 3.49 ERA) makes his 21st start and 26th appearance. He has a 1.31 WHIP, 2.9 BB/9 and 6.9 K/9 in 113 1/3 IP.

  • Last start: Loss, 4 1/3 IP, 6 ER, 8 H, 2 BB, 2 K in 8-1 home loss against Chicago White Sox Wednesday
  • 2024 away splits: 4-3, 3.75 ERA (57 2/3 IP, 25 R (24 ER), 1.37 WHIP, 7.2 K/9 in 15 games
  • Last start vs Red Sox: Win, 6 IP, 0 ER, 7 H, 0 BB, 6 K in 4-2 home win Aug. 18

Crawford (8-13, 4.08 ERA) makes his 30th start. He has a 1.08 WHIP, 2.5 BB/9 and 8.3 K/9 in 161 IP.

  • Last start: Loss, 6 IP, 2 ER, 1 H, 2 BB, 8 K in 7-2 road loss against New York Mets Tuesday
  • 2024 home splits: 4-7, 4.06 ERA (82 IP, 42 R (37 ER), 1.10 WHIP, 8.2 K/9 in 15 starts
  • 2024 vs Orioles: 0-2, 4.41 ERA (16 1/3 IP, 8 ER), 0.93 WHIP, 8.4 K/9 in 3 starts

Who’s going yard? Here’s a breakdown of today’s best home run props with our top picks. Include the BetMGM bonus code SBWIRE to score a $1,500 first-bet offer.

Orioles at Red Sox odds

Provided by FanDuel Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated 12:46 a.m. ET.

  • Moneyline (ML): Orioles -102 (bet $102 to win $100) | Red Sox -116 (bet $116 to win $100)
  • Run line (RL)/Against the spread: Orioles -1.5 (+152) | Red Sox +1.5 (-184)
  • Over/Under (O/U): 9.5 (O: -115 | U: -105)

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Orioles at Red Sox picks and predictions

Prediction

Orioles 4, Red Sox 2

Moneyline

BET ORIOLES (-102).

Baltimore is right in the mix for the AL East title, just a half-game behind the Yankees, and they’ve had Boston’s number this season, winning 7 of their 10 matchups and outscoring them 63-42. The Orioles have been solid on the road (40-29), and they’re looking to bounce back after dropping 3 of their last 4 at home.

The Red Sox, on the other hand, have been struggling, losing 6 of their last 8 games. Suarez shut down Boston in his earlier start against them, while Crawford has been shaky against Baltimore, going winless in his last 3 starts with 8 ER in 16 1/3 IP.

Run line/Against the spread

PASS.

I don’t love the odds, so I’ll keep my focus on the moneyline and total.

Over/Under

BET UNDER 9.5 (-105).

I’m leaning toward the UNDER 9.5 (-105) because recent matchups between these 2 have favored the Under, hitting in 3 of the last 5 games, including this same pitching matchup on Aug. 18. Both teams have hit the Under in 2 of their last 3 games.

Suarez has had the Under hit in 5 of his last 6 starts, and Crawford’s been on a similar run, with the Under hitting in 3 of his last 4 starts. With these trends, it’s looking like a low-scoring game might be on the horizon.

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Baltimore Orioles at Boston Red Sox odds, picks and predictions

Analyzing Thursday’s Baltimore Orioles at Boston Red Sox odds and lines, with MLB expert picks, predictions and best bets.

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The Boston Red Sox (7-5) welcome the Baltimore Orioles (7-4) to Fenway Park Thursday. First pitch in the finale of the 3-game series is set for 7:10 p.m. ET. Let’s analyze FanDuel Sportsbook’s lines around the Orioles at Red Sox odds and make our expert MLB picks and predictions for the best bets.

Season series: Orioles lead 2-0

The Red Sox had won 6 of their last 7 coming into this series against Baltimore but Boston has dropped the 1st 2 games by a combined 14-6 after Wednesday’s 7-5 loss. Boston is 8-4 against the spread (ATS) and sits 3rd in the American League East.

The Orioles sit 2nd in the division and have won 4 of their last 6 games. They are 6-5 ATS on the season and 3-2 straight up on the road. Baltimore finished 1st in the division last season and was the only AL team to win 100+ games.

Orioles at Red Sox projected starters

RHP Grayson Rodriguez vs. RHP Garrett Whitlock

Rodriguez (2-0, 2.19 ERA) makes his 3rd start. He has a 1.05 WHIP, 2.2 BB/9 and 11.7 K/9 in 12 1/3 IP.

  • Last start: Win, 6 1/3 IP, 2 ER, 6 H, 2 BB, 7 K in 5-2 road win over the Pittsburgh Pirates Friday
  • 2023 away splits: 3-2, 4.08 ERA (57 1/3 IP, 26 ER — 8 HR), 18 BB, 69 K in 11 starts

Whitlock (1-0, 0.96 ERA) makes his 3rd start. He has a 1.18 WHIP, 3.9 BB/9 and 11.6 K/in 9 1/3 IP.

  • Last start: No-decision, 4 1/3 IP, 0 ER, 4 H, 4 BB, 4 K in 2-1 road loss to the Los Angeles Angels Saturday
  • 2023 home splits: 3-1, 4.37 ERA (35 IP, 17 ER — 2 HR), 10 BB, 38 K in 10 appearances (4 starts)

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Orioles at Red Sox odds

Provided by FanDuel Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 10:16 a.m. ET.

  • Moneyline (ML): Orioles -122 (bet $122 to win $100) | Red Sox +104 (bet $100 to win $104)
  • Run line (RL)/Against the spread (ATS): Orioles -1.5 (+132) | Red Sox +1.5 (-160)
  • Over/Under (O/U): 8.5 (O: -114 | U: -106)

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Orioles at Red Sox picks and predictions

Prediction

Red Sox 4, Orioles 3

Moneyline

BET RED SOX (+104).

Whitlock has been terrific this season. The Red Sox have allowed 3 runs in his 2 starts. Boston has scored at least 5 runs in 3 of its last 5 games, so if that offense stays consistent with how Whitlock has been pitching, it could get its 1st home win of the season.

The Orioles are 3-3 straight up following a win and have allowed 6 runs through Rodriguez’s 2 starts. It isn’t easy to sweep teams and is even more difficult on the road. Expect Boston to be able to the 3rd game of the series with how well Whitlock has pitched. Take RED SOX (+104).

Run line/Against the spread

PASS.

There isn’t much value here either way as the Red Sox are too expensive as a run line underdog, and the Orioles aren’t worth the gamble as a plus-money favorite.

Over/Under

LEAN UNDER 8.5 (-106).

The pitchers have been too good to expect many runs in this game. The Red Sox are 0-2 O/U in games that Whitlock has started while the Orioles are 1-1 O/U in games Rodriguez has started.

They are 2-3-2 O/U in their last 7 games as well. Baltimore has scored 4 or fewer in 2 of its last 4 and allowed 5 or fewer in every game this season. Considering those trends, back UNDER 8.5 (-106).

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Baltimore Orioles at Boston Red Sox odds, picks and predictions

Analyzing Sunday’s Baltimore Orioles at Boston Red Sox odds and lines, with MLB expert picks, predictions and best bets.

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The Baltimore Orioles (90-51) face the Boston Red Sox (72-70) Sunday in the finale of a 3-game series. First pitch from Fenway Park is at 1:35 p.m. ET. Let’s analyze BetMGM Sportsbook’s lines around the Orioles vs. Red Sox odds and make our expert MLB picks and predictions for the best bets.

Season series: Orioles lead 5-3 after a 13-12 victory Saturday

Boston jumped to an early lead thanks to a 2-run home run by DH Justin Turner in the 1st inning. However, Baltimore would strike back and score 7 runs to lead 7-2 through the top of the 4th inning.

The Red Sox responded with 4 runs in the bottom of the frame and only trailed by 1 run heading into the 6th. The Orioles plated 2 in the 6th and both squads added 3 in the 7th inning. Baltimore added 1 more in the top of the 9th to take the lead for good despite Red Sox SS Trevor Story hitting a 2-run double followed by CF Wilyer Abreu’s RBI single to cut to get back within a single run.

Orioles at Red Sox projected starters

RHP Grayson Rodriguez vs. RHP Brayan Bello

Rodriguez (5-3, 4.91 ERA) makes his 20th start. He has a 1.36 WHIP, 3.4 BB/9 and 9.5 K/9 through 99 IP.

  • Last start: Win, 6 IP, 2 ER, 7 H, 2 BB, 7 K in 6-3 road win vs. Los Angeles Angels on Monday
  • 2023 road stats: 3-1, 4.13 ERA (48 IP, 22 ER) in 9 starts
  • First career start vs. Red Sox

Bello (11-8, 3.61 ERA) makes his 25th start. He has a 1.28 WHIP, 2.5 BB/9 and 7.4 K/9 through 137 IP.

  • Last start: Win, 6 IP, 3 ER, 5 H, 2 BB, 7 K in 7-3 road win vs. Tampa Bay Rays on Monday
  • 2023 home stats: 4-6, 3.44 ERA (70 2/3 IP, 27 ER) in 13 starts
  • Career vs. Orioles: 0-1, 5.06 ERA (5 1/3 IP, 3 ER) in 1 start

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Orioles at Red Sox odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 7:13 a.m. ET.

  • Moneyline (ML): Orioles -105 (bet $105 to win $100) | Red Sox -115 (bet $115 to win $100)
  • Run line (RL)/Against the spread (ATS): Orioles -1.5 (+150) | Red Sox +1.5 (-185)
  • Over/Under (O/U): 10 (O: -105 | U: -115)

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Orioles at Red Sox picks and predictions

Prediction

Red Sox 7, Orioles 4

Moneyline

Bello has a better ERA at Fenway than on the road despite having a better record away from home, but that is the only bright spot for Boston as they look to avoid the sweep. There are just too many reasons to pick Baltimore to win, again.

The Orioles have an MLB-best 65.8% win rate on the road and a 62.9% win percentage after a win. The Red Sox win just 42% of the time after a loss.

BET ORIOLES (-105).

Run line/Against the spread

Boston is 42-31 ATS as an underdog, but its 14-13 ATS as a home underdog. The Red Sox have the 2nd worst ATS record after a loss in the league (27-42). Even if their numbers painted a brighter picture the current odds don’t bring a lot of value.

Baltimore’s trends and their plus-money odds are the better pick ATS. The Orioles are the best team in baseball as a favorite ATS (53.3% win rate) and they are 19-7 ATS as a road favorite — a 73.1% cover rate.

LEAN ORIOLES -1.5 (+150).

Over/Under

In divisional games both the Orioles (57.1%) and the Red Sox (63.2%) trend towards the Over. Boston’s Over record after a loss (38-30-1) is nearly as good as Baltimore’s Over record after a win (48-36-5).

The books also anticipate a higher-scoring game and set the line accordingly but based on yesterday’s game each team can go on a scoring streak.

LEAN OVER 10 (-105).

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Baltimore Orioles at Boston Red Sox odds, picks and predictions

Analyzing Saturday’s Baltimore Orioles at Boston Red Sox odds and lines, with MLB expert picks, predictions and best bets.

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The Baltimore Orioles (89-51) and Boston Red Sox (72-69) play game 2 of a 3-game series at Fenway Park Saturday. First pitch is slated for 4:10 p.m. ET. Let’s analyze Fanduel Sportsbook’s lines around the Orioles vs. Red Sox odds and make our expert MLB picks and predictions for the best bets.

Season series: Orioles lead 4-3

The Orioles picked up a  6th straight victory with a 7-2 win in the series opener Friday. Baltimore is in the midst of a 9-game road trip where it has outscored its opponents 49 to 24 through 7 games and has improved to 47-25 away from Camden Yards this season.

Boston began a 7-game homestand Friday. That was the Red Sox’s 6th loss in their last 7 games at Fenway Park. They’ve allowed 7 runs per game over that 8-game span at Fenway and are 36-34 at home on the season.

Orioles at Red Sox projected starters

RHP Jack Flaherty vs. LHP Chris Sale

Flaherty (8-8, 4.84 ERA) makes his 26th start. He has a 1.55 WHIP, 4.3 BB/9 and 9.1 K/9 in 134 innings for the Orioles and St. Louis Cardinals.

  • Last start: No-decision, 4 2/3 IP, 4 ER, 6 H, 1 BB, 7 K in 8-5 road loss vs. Arizona Diamondbacks Sunday
  • Has never started against the Red Sox
  • 2023 road stats: 4-4, 4.39 ERA (82 IP, 40 ER), .287 opponent batting average (OBA) in 15 starts

Sale (6-3, 4.46 ERA) will make his 17th start. He has a 1.16 WHIP, 2.5 BB/9 and 11.0 K/9 in 82 2/3 innings.

  • Last start: Win, 5 IP, 0 ER, 2 H, 0 BB, 5 K in 7-3 road win vs. Kansas City Royals Sunday
  • 2023 vs. Orioles: 0-1, 13.50 ERA (8 IP, 12 ER), 2 HR, 3 BB, 6 K in 2 starts
  • 2023 home stats: 0-1, 3.96 ERA (36 1/3 IP, 16 ER), .212 OBA in 7 starts

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Orioles at Red Sox odds

Provided by Fanduel Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 7:35 a.m. ET.

  • Moneyline (ML): Orioles +120 (bet $100 to win $120) | Red Sox -142 (bet $142 to win $100)
  • Run line (RL)/Against the spread (ATS): Orioles +1.5 (-164) | Red Sox -1.5 (+136)
  • Over/Under (O/U): 10 (O: +100 | U: -122)

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Orioles at Red Sox picks and predictions

Prediction

Orioles 7, Red Sox 4

Moneyline

BET ORIOLES (+120).

Everything is working for the Orioles right now. Baltimore has notched 6 straight road wins, so obviously being away from Charm City does not matter at this point. Baltimore is scoring 7 runs per game on a 7-game road trip.

Sale has been owned by the Orioles this season only making it through 8 innings over 2 starts giving up 12 earned runs.

Run line/Against the spread

PASS.

I am confident that the Orioles will cover this run line but I’m not going to bet it at -164 odds. Focus your bet on the moneyline.

Over/Under

AVOID.

If I had a lean, it would be to the Over, but I don’t have a good feeling either way. In their 7 games played against each other this season, they have gone Over this total in 5 of them.

This bet will come down to whether Chris Sale can keep the Orioles’ offense in check.

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Baltimore Orioles at Boston Red Sox odds, picks and predictions

Analyzing Friday’s Baltimore Orioles at Boston Red Sox odds and lines, with MLB expert picks, predictions and best bets.

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The Baltimore Orioles (88-51) continue their trek toward the top seed in the American League as they open a 3-game weekend series against the Boston Red Sox (72-68) Friday. First pitch from Fenway Park is at 7:10 p.m. ET. Let’s analyze BetMGM Sportsbook’s lines around the Orioles vs. Red Sox odds and make our expert MLB picks and predictions for the best bets.

Season series: tied 3-3

The Orioles are red-hot and threatening to run away in the AL East race. They have won 5 games in a row and 14 of their last 18 contests, and their 46-25 road record is 2nd best in the league behind the Atlanta Braves (46-24).

The Red Sox just finished a 3-3 road trip against the Kansas City Royals and Tampa Bay Rays. Boston lost its last 2 games vs. the Rays but now returns home where it is 36-33 on the season.

Orioles at Red Sox projected starters

RHP Kyle Bradish vs. RHP Tanner Houck

Bradish (10-6, 3.03 ERA) makes his 26th start. He has a 1.11 WHIP, 2.5 BB/9 and 8.8 K/9 through 139 2/3 IP.

  • Last start: Win, 6 IP, 2 ER, 4 H, 3 BB, 6 K in 7-3 road victory at Arizona Diamondbacks Saturday
  • 2023 road stats: 6-3, 3.60 ERA (80 IP, 32 ER) with 9.5 K/9 in 15 starts
  • Career vs. Red Sox: 0-4, 9.36 ERA (25 IP, 26 ER) with a 17/12 K/BB in 6 starts
  • 2023 vs. Red Sox: Loss, 2 1/3 IP, 7 ER, 8 H, 4 BB, 1 K in 8-6 home loss on April 25 in his worst start of the season

Houck (4-8, 5.07 ERA) makes his 17th start. He has a 1.31 WHIP, 3.2 BB/9 and 8.3 K/9 through 81 2/3 IP.

  • Last start: Win, 5 IP, 4 ER, 7 H, 1 BB, 5 K in 9-5 victory at Royals Saturday
  • 2023 home stats: 2-3, 5.40 ERA (40 IP, 24 ER), with 9.0 K/9 across 8 starts
  • Career vs. Orioles: 3-2, 3.28 ERA (24 2/3 IP, 9 ER) through 3 starts and 4 relief appearances
  • 2023 vs. Orioles: 1-1, 5.40 ERA (10 IP, 6 ER) across 2 starts in April

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Orioles at Red Sox odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 12:55 p.m. ET.

  • Moneyline (ML): Orioles -125 (bet $125 to win $100) | Red Sox +105 (bet $100 to win $105)
  • Run line (RL)/Against the spread (ATS): Orioles -1.5 (+125) | Red Sox +1.5 (-155)
  • Over/Under (O/U): 10 (O: -115 | U: -105)

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Orioles at Red Sox picks and predictions

Prediction

Orioles 6, Red Sox 5

Moneyline

Bradish has had an excellent season and has taken his skills up a notch lately,  registering a 2.25 ERA (24 IP, 6 ER) while whiffing 31% of opposing batters over his last 4 starts. He’s had some struggles against Boston, with 3 blowups in 6 career starts, but the sample is too small to be overly concerned. Both Bradish and his team have been rolling and have shown no signs of slowing down so back the ORIOLES (-125).

Run line/Against the spread

Houck has been a little shaky in 3 starts since coming off the IL (14 IP, 8 ER, 6 BB, 11 K), but he faced the Houston Astros and Los Angeles Dodgers in 2 of those, and he has displayed strong skills throughout most of the season. He’ll have his hands full against a Baltimore team that is firing on all cylinders, but this sets up to be a pretty tight game.

PASS.

Over/Under

The Baltimore offense has been hot, with 5-plus runs in 8 of their last 9 games and 12 of their last 14. They rank 5th in runs per game on the road this season (5.39), while the Red Sox are 5th in runs per game at home (5.25). Look for this game to just sneak past OVER 10 (-115).

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Baltimore Orioles at Boston Red Sox odds, picks and predictions

Analyzing Sunday’s Baltimore Orioles at Boston Red Sox odds and lines, with MLB expert picks, predictions and best bets.

The Baltimore Orioles (1-1) and Boston Red Sox (1-1) close out their season-opening 3-game series at Fenway Park on Sunday. First pitch is set for 1:35 p.m. ET. Let’s analyze BetMGM Sportsbook’s lines around the Orioles vs. Red Sox odds and make our expert MLB picks and predictions for the best bets.

Season series: Tied 1-1

The Orioles took Thursday’s lid-lifter 10-9. The Red Sox bounced back with a dramatic 9-8 win on Saturday.

The Red Sox were trailing 8-7 on Saturday, but won when CF Adam Duvall hit a 2-out, 2-run HR in the bottom of the 9th. The walk-off HR capped a comeback from a 7-1 deficit in the the 3rd inning.

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Orioles at Red Sox projected starters

LHP Cole Irvin vs. RHP Tanner Houck

Irvin pitched for Oakland last season, going 9-13 with a 3.98 ERA. He notched a 1.16 WHIP, 1.8 BB/9 and 6.4 K/9 in 181 IP.

  • Owns a 4.40 ERA over 405 career IP
  • Faces what figures to be a left-leaning Boston lineup; held lefty batters to a .638 OPS last season

Houck went 5-4 with a 3.15 last season. He appeared in 32 games (4 as a starter) and logged a 1.18 WHIP, 3.3 BB/9 and 8.4 in 60 IP.

  • Has held opposing batters to a .658 OPS in 8 career April games (5 starts)
  • Albeit in a small sample, he has held current Baltimore bats to an aggregate .528 OPS

Orioles at Red Sox odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 8:43 a.m. ET.

  • Moneyline: Orioles +120 (bet $100 to win $120) | Red Sox -145 (bet $145 to win $100)
  • Run line (RL)/Against the spread (ATS): Orioles +1.5 (-165) | Red Sox -1.5 (+135)
  • Over/Under (O/U): 9 (O: -105 | U: -115)

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Orioles at Red Sox picks and predictions

Prediction

Boston 6, Baltimore 5

Moneyline

This has been a level series the last couple of years, and both starting pitchers are fade-worthy, being slightly overrated by their 2022 surface numbers. PASS, and look to the Over for the best leverage.

Run line/Against the spread

The Red Sox are a theoretical lean here, but the 30-cent line is tough to work around. PASS.

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Over/Under

The weather is a factor (temps not expected to reach 40), but the play here is to follow games 1 and 2 into the Over column. A depth of batters on each side is dialed in so far. The starters both had favorable numbers around the margins last season and are a bit overrated on paper. And neither bullpen is in great shape after the 36 runs scored so far.

TAKE THE OVER 9 (-105).

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Baltimore Orioles at Boston Red Sox odds, picks and predictions

Analyzing Saturday’s Baltimore Orioles at Boston Red Sox odds and lines, with MLB expert picks, predictions and best bets.

The Baltimore Orioles (1-0) and Boston Red Sox (0-1) meet Saturday for the 2nd game of their 3-game season-opening series at Fenway Park. First pitch is set for 4:10 p.m. ET. Let’s analyze BetMGM Sportsbook’s lines around the Orioles vs. Red Sox odds and make our expert MLB picks and predictions for the best bets.

Season series: Baltimore leads 1-0.

The Orioles took Thursday’s lid-lifter 10-9. They have split 20 games with Boston since the beginning of last season. Baltimore has been outscored just 115-113 over those meetings.

The Red Sox played .769 ball last June but are 17 games under .500 since (35-52). The Orioles swiped 5 bases in Thursday’s game, the most stolen bases Boston had yielded in a single game since Sept. 5, 2013, when they allowed 6 to the New York Yankees.

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Orioles at Red Sox projected starters

RHP Dean Kremer vs. LHP Chris Sale

Kremer went 8-7 with a 3.23 ERA last season. He notched 1.25 WHIP, 2.4 BB/9 and 6.3 K/9 in 125 1/3 IP.

  • vs. Boston in 2022: 4.50 ERA, 1.50 WHIP across 16 IP
  • current Red Sox batters aggregate vs. Kremer: .312 AVG, .940 OPS

Sale was injured for much of 2022; he pitched in 2 games, clocking a 3.18 ERA in 5 2/3 IP. He owns a 114-75 mark and a 3.03 ERA over his 12-year career.

  • Pitching in April for the 1st time since 2019 when he allowed a .740 OPS
  • current Orioles vs. Sale: .195 AVG, .653 OPS, 17 K, 1 BB

Orioles at Red Sox odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 7:37 a.m. ET.

  • Moneyline: Orioles +140 (bet $100 to win $140) | Red Sox -167 (bet $167 to win $100)
  • Run line (RL)/Against the spread (ATS): Orioles +1.5 (-139) | Red Sox -1.5 (+115)
  • Over/Under (O/U): 9 (O: -105 | U: -115)

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Orioles at Red Sox picks and predictions

Prediction

Boston 6, Baltimore 5

Moneyline

This has been a level series the last couple of years, and both starting pitchers have some warts in Saturday’s match-up. PASS, and look to the Over for the best leverage.

Run line/Against the spread

The Orioles getting runs would be the only half-interesting play here. Even then, we should be wanting a lower price tag there.

PASS.

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Over/Under

A bit of a warm-up and an outward-blowing breeze is in the Fenway forecast. Both starters a fade-worth: neither was particularly sharp in spring training, and Kremer’s 2022 campaign stands out as one aided by a friendly 77.8% left-on-base rate and an HR/FB mark of 7.3%. The Baltimore righty owns a 9.45 ERA across 3 career turns at Fenway Park.

TAKE THE OVER 9 (-105).

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Additional MLB coverage:
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Baltimore Orioles at Boston Red Sox odds, picks and predictions

Analyzing Thursday’s Baltimore Orioles at Boston Red Sox odds and lines, with MLB expert picks, predictions and best bets.

The Baltimore Orioles and Boston Red Sox kick off their 2023 seasons with a Thursday matchup in Fenway Park. First pitch is set for 2:10 p.m. ET. Let’s analyze Tipico Sportsbook’s lines around the Orioles vs. Red Sox odds and make our expert MLB picks and predictions for the best bets.

Season series: First of 13 meetings in 2023; Boston won last year’s season series 10-9.

Baltimore finished last season 83-79 and 4th in the AL East, 16 games behind the 1st-place New York Yankees. Their record last year was greatly improved from a 52-110 record in 2021.

The Red Sox finished 78-84 last season, 5th in the AL East and 5 games behind the Orioles. Boston took a major step back after  a 92-70 mark and 2nd-place finish in 2021.

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Orioles at Red Sox projected starters

RHP Kyle Gibson vs. RHP Corey Kluber

Gibson went 10-8 with a 5.05 ERA last year. He had a 1.336 WHIP, 2.58 BB/9 and 7.73 K/9 in 167.2 IP.

  • Was 2-1 in 5 March/April starts with a 2.93 ERA and 1.084 WHIP
  • In 13 road starts last season he was 3-4 with a 5.79 ERA and 1.408 WHIP

Kluber went 10-10 with a 4.34 ERA last year, posting a 1.213 WHIP and 1.15 BB/9 and 7.63 K/9 in 164 IP.

  • Was 1-1 in 4 March/April starts with a 3.05 ERA and 1.161 WHIP
  • In 15 starts at home last year, he went 7-3 with a 3.71 ERA and 1.088 WHIP

Orioles at Red Sox odds

Provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Wednesday at 10:39 p.m. ET.

  • Moneyline (ML): Orioles +105 (bet $105 to win $100) | Red Sox -125 (bet $100 to win $125)
  • Run line (RL)/Against the spread (ATS): Orioles +1.5 (-180) | Red Sox -1.5 (+155)
  • Over/Under (O/U): 9 (O: -111 | U: -109)

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Orioles at Red Sox picks and predictions

Prediction

Red Sox 5, Orioles 3

Moneyline

BET RED SOX -125.

Boston was 6-0 in its last 6 home games last season and 4-0 in their last 4 vs. a right-handed starter. The Orioles struggled at the end vs. Boston, going 1-5 in the last 6 meetings and 1-4 in the last 5 games in Boston. Look for Boston to come out hot on Opening Day vs. this divisional rival.

Run line/Against the spread

LEAN RED SOX -1.5 (+155).

Seven of the last 10 meetings last year were decided by 2 or more runs, with the Red Sox winning 4 of the 7. The Red Sox will have the advantage as the home team and recent history suggests they should be the slight lean here.

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Over/Under

BET UNDER 9 (-110).

In 6 of the last 10 meetings between these teams the final score was Under 9 total runs, the Under during that stretch was also 6-4. The Under is also 5-1 in Baltimore’s last 6 games vs. a right-handed starter.

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For sports betting picks and tips, check out SportsbookWire.com and BetFTW. Plus, try out the USA TODAY Parlay Calculator and please gamble responsibly.

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