Oregon vs. USC odds: USC mild favorites over Oregon in Sweet 16

Previewing Saturday’s Oregon Ducks vs. USC Trojans odds and lines during their March Madness Sweet 16 matchup.

The 7th-seed Oregon Ducks (22-6) will meet the 6th-seed USC Trojans (24-7) at Bankers Life Fieldhouse in Indianapolis Sunday at 9:45 p.m. ET on TBS in the East Region.

Today we’re taking an early look at the March Madness Sweet 16 matchup Oregon-USC odds and lines. Don’t forget to check out all of the remaining teams’ March Madness odds, and check back later in the week for our full Sweet 16 breakdowns, picks and predictions.

The Ducks essentially had a first-round bye due to the unfortunate situation with VCU and COVID protocols. Oregon was awarded the win by no contest, but that didn’t affect them heading into the second round. The Ducks were able to power past two-seed Iowa in the second round by a 95-80 score as 4.5-point underdogs as the Over (151.5) comfortably connected. UO had four players in double digits, led by Chris Duarte with 23 and LJ Figueroa with 21. The latter also added seven rebounds while hitting five triples.

The Trojans were bumped from the Pac-12 tourney against Colorado, falling 72-70 March 12. That loss really lit a fire under USC, as it’s playing their best basketball, perhaps of the entire season. USC trounced Drake by a 72-56 count in the first round, easily covering a 7.5-point number as the Under (135) connected. That paled in comparison to the amazing display against third-seed Kansas, as the Trojans rolled to an 85-51 rout, showing why the lower seed was actually favored by 1.5 points. These teams met just once in the regular season, with USC topping Oregon 72-58 as 3.5-point favorites Feb. 22 in Los Angeles as the Under (139.5) cashed.

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Oregon vs. USC: Odds, spread and lines

Odds via BetMGM; access USA TODAY Sports’ betting odds for a full list. Lines last updated Tuesday at 7:45 a.m. ET.

  • Money line: Oregon +100 (bet $100 to win $100) | USC -120 (bet $120 to win $100)
  • Against the spread/ATS: Oregon +1 (-110) | USC -1 (-110)
  • Over/Under: 138.5 (O: -110 | U: -110)

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