Ole Miss at Louisville odds, picks and predictions

Analyzing Tuesday’s Ole Miss at Louisville odds and lines, with college basketball expert picks, predictions and best bets.

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The Ole Miss Rebels (6-1) and Louisville Cardinals (5-2) meet for a 9 p.m. ET (ACC Network) Tuesday game at the KFC Yum! Center. Let’s analyze BetMGM Sportsbook’s college basketball odds around the Ole Miss vs. Louisville odds, and make our expert college basketball picks and predictions.

Ole Miss — No. 20 in the USA TODAY Sports Men’s Basketball Coaches Poll —  was undefeated until falling 80-78 to Purdue in the championship game of the Rady Children’s Invitational (San Diego) Friday. A Myles Colvin putback on a final-seconds missed jumper sealed the win for the Boilermakers and marked the Rebels’ first November loss since Nov. 27, 2022. Mississippi was a +3 against PU and has won 4 in a row against the spread (ATS).

Louisville had a 4-game win streak snapped Friday vs. Oklahoma. The favored-by-3 Cardinals were defeated 69-64 in the title game of the Battle 4 Atlantis tournament in Nassau, Bahamas. UL was undone by shooting just 21.9% from 3-point range and 56.3% from the free-throw line.

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Ole Miss at Louisville odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list of college basketball odds. Lines last updated at 11:55 a.m. ET.

  • Moneyline: Ole Miss +125 (bet $100 to win $125) | Louisville -155 (bet $155 to win $100)
  • Against the spread: Ole Miss +2.5 (-105) | Louisville -2.5 (-115)
  • Over/Under (O/U): 151.5 (O: -115 | U: -105)

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Ole Miss at Louisville picks and predictions

Prediction

Louisville 79, Ole Miss 78

Moneyline

No interest. PASS.

Against the spread

Louisville is 2-6 ATS in its last 8 games at home.

Mississippi has been solid enough against top-third foes, and UM’s 40.3% 3-point shooting away from Oxford (3 neutral-site games) is an intriguing stat. The much smaller rebels likely won’t find much success against UL inside.

Louisville’s distance shooting has been quite bad. The Cardinals’ 28.7% mark from beyond the arc ranks 297th in the nation.

UL’s attention may be a couple days down the road on a Sunday home game against Duke.

Consider a partial-unit play on OLE MISS +2.5 (-105).

Over/Under

The Over has cashed in 4 consecutive Ole Miss games and in 4 out of the Rebels’ last 5 on the road.

Fast-paced Louisville has played with some Under tilt (7-1 to the Under), but the OVER 151.5 (-115) is the value side here. Both teams are quite good in getting quick looks off turnovers, and a decent number of tosses from the charity stripe figure to be in the mix.

There is the chance distance-heavy Louisville catches fire and gets a lot in 3-by-3 fashion, and UM’s accuracy mark has to be considered. Also consider both sides logged some tough games (including overtime contests) last week. Tired legs make for slow-by-a-step defenders.

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