Ohio State at Michigan State odds, picks and predictions

Analyzing Saturday’s Ohio State at Michigan State odds and lines, with college football expert picks, predictions and best bets.

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The 3rd-ranked Ohio State Buckeyes (3-0, 0-0 Big Ten) travel to meet the Michigan State Spartans (3-1, 1-0) Saturday in a conference game at Spartan Stadium. Kickoff is scheduled for 7 p.m. ET (Peacock). Let’s analyze BetMGM Sportsbook’s college football odds around the Ohio State vs. Michigan State odds, and make our expert college football picks and predictions.

The Buckeyes have rolled Akron, Western Michigan and Marshall to start the season, but that isn’t exactly a gauntlet. Ohio State has scored 49 or more points in each of the 3 wins, which have come by 35 or more points. The Over has cashed in all 3 outings for Ohio State.

The Spartans play their 2nd conference game of the season. Michigan State topped Maryland 27-24 on the road as an 8.5-point underdog as the Over (44.5) cashed. That was the only time the total has gone high in 4 games for Sparty.

Michigan State followed the win over Maryland with a 40-0 victory against Prairie View A&M, but it suffered a 23-19 loss at Boston College last week in the emotional Red Bandanna game for the Eagles. MSU did hang on for the cover as a 5-point underdog.

– Rankings: US LBM Coaches Poll, conducted by the American Football Coaches Association and USA TODAY Sports

Stream select live college football games and full replays: Get ESPN+

Ohio State at Michigan State odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list of college football odds. Lines last updated at 1:15 a.m. ET.

  • Moneyline (ML): Ohio State -3000 (bet $3,000 to win $100) | Michigan State +1300 (bet $100 to win $1,300)
  • Against the spread: Ohio State -23.5 (-115) | Michigan State +23.5 (-105)
  • Over/Under (O/U): 48.5 (O: -110 | U: -110)

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Ohio State at Michigan State picks and predictions

Prediction

Ohio State 45, Michigan State 16

Moneyline

Ohio State (-3000) will cost you 30 times your potential return. In other words, if you risk $100, you make just $3.33 in profit. It should go without saying, but taking such heavy favorites is a foolish wager and a terrible long-term betting strategy.

AVOID.

Against the spread

This is a big number, but OHIO STATE -23.5 (-115) is worth a look at this price.

The Buckeyes have won the past 8 meetings in this series since Nov. 19, 2016, and each of the past 5 wins in the series have been by 24 or more points. The average winning margin is 34.6 PPG in the past 7 wins by Ohio State in this series, too.

Over/Under

OVER 48.5 (-110) might be the strongest play on the board in this Big Ten battle.

The Buckeyes have collected the Over in all 3 games to date, going for 49 or more points in each outing.

The Over has also cashed in each of the past 2 meetings in East Lansing, with the winning team collecting 49 or more points in 3 of the past 4 outings in the series. It’s very possible Ohio State could take on this total all on its own.

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For more sports betting picks and tips, check out SportsbookWire.com and BetFTW.

Follow Kevin J. Erickson on Twitter/X. Follow SportsbookWire on Twitter/X and like us on Facebook.

College sports coverage from USA TODAY Sports Media Group:
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First look: Ohio State at Michigan State odds and lines

Looking at Saturday’s Ohio State at Michigan State college football odds, lines and trends. Here’s what you need to know.

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The 3rd-ranked Ohio State Buckeyes (3-0, 0-0 Big Ten) and the Michigan State Spartans (3-1, 1-0) meet Saturday in a conference matchup at Spartan Stadium. Kickoff is scheduled for 7 p.m. ET (Peacock). Below, we look at Ohio State vs. Michigan State odds from BetMGM Sportsbook’s college football odds before making our expert college football picks and predictions later in the week.

The Buckeyes were back Saturday after a bye, and they rolled up a 49-14 win over Marshall as a 40-point favorite while the Over (57) cashed. Ohio State is just 1-2 against the spread (ATS) in 3 games. It has scored 49 or more points in each game, cashing high on the total in each outing.

The Spartans lost 23-19 at Boston College on Saturday night, although it hung on for a cover as a 5-point underdog. It has alternated covers and non-covers in its 4 games, and Michigan State has cashed low on the total in 3 of 4 outings.

– Rankings: US LBM Coaches Poll, conducted by the American Football Coaches Association and USA TODAY Sports

Stream select live college football games and full replays: Get ESPN+

Ohio State at Michigan State odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list of college football odds. Lines last updated Monday at 6:10 a.m. ET.

  • Moneyline (ML): Off the board
  • Against the spread (ATS): Ohio State -24.5 (-110) | Michigan State +24.5 (-110)
  • Over/Under (O/U): 49.5 (O: -110 | U: -110)

FanDuel Sportsbook lists a ML of:

  • Ohio State -4500 (bet $4,500 to win $100)
  • Michigan State +1600 (bet $100 to win $1,600)

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2024 betting stats

  • ML: Ohio State 3-0 | Michigan State 3-1
  • ATS: Ohio State 1-2 | Michigan State 2-2
  • O/U: Ohio State 3-0 | Michigan State 1-3

Ohio State at Michigan State head-to-head

Ohio State leads the all-time series 37-15, while winning 8 in a row in the series. The Buckeyes have covered 7 in a row in the series, too, while the Over has cashed in the past 2 meetings in East Lansing. The Under is 7-2 in the previous 9 battles in the series, however.

The Buckeyes won 38-3 last season on Nov. 11, while posting a 49-20 win in the most recent visit to East Lansing on Oct. 8, 2022.

Play our free daily Pick’em Challenge and win! Play now!

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For more sports betting picks and tips, check out SportsbookWire.com and BetFTW.

Follow Kevin J. Erickson on Twitter/X. Follow SportsbookWire on Twitter/X and like us on Facebook.

College sports coverage from USA TODAY Sports Media Group:
Alabama / Arkansas / Auburn / Clemson / Colorado / DukeFlorida / Florida StateGeorgia / Iowa / KentuckyLSU / Michigan / Michigan State / Nebraska / North Carolina / Notre Dame / Ohio State / Oklahoma / Oregon / Penn State / Rutgers / Tennessee / Texas / Texas A&M / UCLA / USC / WashingtonWisconsin / Recruiting / Transfer portal / College Football Playoffs / College Sports Wire / High School

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